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Water Dispersible Semiconductor Nanorod Assemblies Via a Facile Phase Transfer and Their Application as Fluorescent Biomarkers

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Advanced Nanomaterials and Nanotechnology

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 143))

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Abstract

We demonstrate the formation of water dispersed nanorod assemblies by phase transfer of semiconductor (CdS, CdSe, CdTe) nanorods from the organic to the aqueous using pluronic triblock copolymers. On phase transfer, the randomly dispersed nanorods in the organic medium close pack in the form of discs encapsulated in the hydrophobic core of water dispersible micelles. The assemblies showed excellent cellular uptake exhibiting membrane and cell specific fluorescence at low light intensity under confocal microscopy.

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References

  1. J. Hu, L.-S. Li, W. Yang, L. Manna, L.-W. Wang, A.P. Alivisatos, Linearly polarized emission from colloidal semiconductor quantum rods. Sci. 292, 2060 (2001)

    Article  CAS  Google Scholar 

  2. S.A. Empedocles, R. Neuhauser, K. Shimizu, M.G. Bawendi, Photoluminescence from single semiconductor nanostructures. Adv. Mater. 11, 1243 (1999)

    Article  CAS  Google Scholar 

  3. A.P. Alivisatos, Perspectives on the physical chemistry of semiconductor nanocrystals. J. Phys. Chem. 100, 13226 (1996)

    Article  CAS  Google Scholar 

  4. I. Gur, N.A. Fromer, M.L. Geier, A.P. Alivisatos, Air-stable all-inorganic nanocrystal solar cells processed from solution. Sci. 310, 462 (2005)

    Article  CAS  Google Scholar 

  5. X.F. Duan, Y. Huang, R. Agarwal, C.M. Lieber, Single-nanowire electrically driven lasers. Nat. 421, 241–245 (2003)

    Article  CAS  Google Scholar 

  6. N.C. Greenham, X.G. Peng, A.P. Alivisatos, Charge separation and transport in conjugated-polymer/semiconductor-nanocrystal composites studied by photoluminescence quenching and photoconductivity. Phys. Rev. B: Condens. Matter 54, 17628 (1996)

    Article  CAS  Google Scholar 

  7. J.S. Steckel, J.P. Zimmer, S. Coe-Sullivan, N.E. Stott, V. Bulovic, M.G. Bawendi, Blue luminesce from (CdS) ZnS core shell nanocrystals. Angew. Chem. Int. Ed. 43, 2154 (2004)

    Article  CAS  Google Scholar 

  8. S. Coe, W.K. Woo, M. Bawendi, V. Bulovic, Electroluminescence from single monolayers of nanocrystals in molecular organic devices. Nat. 420, 800 (2002)

    Article  CAS  Google Scholar 

  9. R. Xie, D. Battaglia, X. Peng, Colloidal InP nanocrystals as efficient emitters covering blue to near-infrared. J. Am. Chem. Soc. 129, 15432 (2007)

    Article  CAS  Google Scholar 

  10. T. Zhai, X. Fang, Y. Bando, Q. Liao, X. Xu, H. Zeng, Y. Ma, J. Yao, D. Golberg, Morphology-dependent stimulated emission and field emission of ordered CdS nanostructure arrays. ACS. Nano. 3, 949 (2009)

    Article  CAS  Google Scholar 

  11. K.M. Ryan, A. Mastroianni, K.A. Stancil, H. Liu, A.P. Alivisatos, Electric-field-assisted assembly of perpendicularly oriented nanorod superlattices. Nano. Lett. 6, 1479 (2006)

    Article  CAS  Google Scholar 

  12. S. Ahmed, K.M. Ryan, Self-assembly of vertically aligned nanorod supercrystals using highly oriented pyrolytic graphite. Nano. Lett. 7, 2480 (2007)

    Article  CAS  Google Scholar 

  13. C. O’Sullivan, S. Ahmed, K.M. Ryan, Gold tip formation on perpendicularly aligned semiconductor nanorod assemblies. J. Mater. Chem. 18, 5218 (2008)

    Article  Google Scholar 

  14. C. Kang, C.W. Lai, H.C. Peng, J.J. Shyue, P.T. Chou, 2D self-bundled CdS nanorods with micrometer dimension in the absence of an external directing process. ACS. Nano. 2, 750 (2008)

    Article  CAS  Google Scholar 

  15. Y. Min, M. Akbulut, K. Kristiansen, Y. Golan, J. Israelachvili, The role of inter-particle and external forces in nanoparticle assembly. Nat. Mater. 7, 527 (2008)

    Article  CAS  Google Scholar 

  16. J.K. Jaiswal, H. Mattoussi, M.J. Mauro, S.M. Simon, Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 21, 47 (2003)

    Article  CAS  Google Scholar 

  17. W.J. Parak, D. Gerion, T. Pellegrino, D. Zanchet, C. Micheel, S.C. Williams, R. Boudreau, M.A.L. Gros, C.A. Larabell, A.P. Alivisatos, Biological applications of colloidal nanocrystals. Nanotechnol. 14, R15–R27 (2003)

    Article  CAS  Google Scholar 

  18. L.S. Li, J. Walda, L. Manna, A.P. Alivisatos, Semiconductor nanorod liquid crystals. Nano. Lett. 2, 557 (2002)

    Article  CAS  Google Scholar 

  19. Z. Nie, D. Fava, E. Kumacheva, S. Zou, G.C. Walker, M. Rubinstein, Self-assembly of metal-polymer analogues of amphiphilic triblock copolymers. Nat. Mater. 6, 609 (2007)

    Article  CAS  Google Scholar 

  20. J. Zhuang, A.D. Shaller, J. Lynch, H. Wu, O. Chen, A.D.Q. Li, C.Y. Cao, Cylindrical superparticles from semiconductor nanorods. J. Am. Chem. Soc. 131, 6084 (2009)

    Article  CAS  Google Scholar 

  21. K.M. Ryan, N.R.B. Coleman, D.M. Lyons, J.P. Hanrahan, T.R. Spalding, M.A. Morris, D.C. Steytler, R.K. Heenan, J.D. Holmes, Control of pore morphology in mesoporous silicas synthesized from triblock copolymer templates. Langmuir 18, 4996 (2002)

    Article  Google Scholar 

  22. A.V. Kabanov, E.V. Batrakova, V.Y. Alakhov, Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. J. Controlled Release 82, 189 (2002)

    Article  CAS  Google Scholar 

  23. H. Liu, J.S. Owen, A.P. Alivisatos, Mechanistic study of precursor evolution in colloidal group II–VI semiconductor nanocrystal synthesis. Am. Chem. Soc. 129, 305 (2007)

    Article  CAS  Google Scholar 

  24. H. Htoon, J.A. Hollingworth, A.V. Malko, R. Dickerson, V.I. Klimov, Light amplification in semiconductor nanocrystals: Quantum rods versus quantum dots. Appl. Phys. Lett. 82, 4776 (2003)

    Article  CAS  Google Scholar 

  25. U. Westedt, L. Barbu-Tudoran, A.K. Schaper, M. Kalinowski, H. Alfke, T. Kissel, Deposition of nanoparticles in the arterial vessel by porous balloon catheters: Localization by confocal laser scanning microscopy and transmission electron microscopy. AAPS PharmSciTech. 4, 206 (2002)

    Article  Google Scholar 

  26. J.W.M. Bulte, M.M.J. Modo (eds.), Nanoparticles in biomedical imaging emerging technologies and applications in fundamental biomedical technologies, vol 3 (Springer, New York, 2008)

    Google Scholar 

  27. A. Merkoci, Electrochemical biosensing with nanoparticles. FEBS J 274, 310 (2007)

    Article  CAS  Google Scholar 

  28. F. Gentile, M. Ferrari, P. Decuzzi, The transport of nanoparticles in blood vessels: The effect of vessel permeability and blood rheology. Ann. Biomed. Eng. 36, 254 (2008)

    Article  Google Scholar 

  29. T. Vo-Dinh (ed.), Biofunctionalization of fluorescent nanoparticles, nanotechnology in biology and medicine—methods, devices and applications (Taylor & Francis Group, Boca Raton, 2007)

    Google Scholar 

  30. J.L. Swift, D.T. Cramb, Nanoparticles as fluorescence labels: Is size all that matters. Biophys. J. 95, 865 (2008)

    Article  CAS  Google Scholar 

  31. D.P. Kalogianni, T. Koraki, T.K. Christopoulos, P.C. Ioannou, Nanoparticle-based DNA biosensor for visual detection of genetically modified organisms. Biosens. Bioelectron. 2006, 21 (1069)

    Google Scholar 

  32. W.-J. Chen, P.-J. Tsai, Y.-C. Chen, Functional nanoparticle-based proteomic strategies for characterization of pathogenic bacteria. Anal. Chem. 81, 1722 (2009)

    Article  CAS  Google Scholar 

  33. H.M.E. Azzazy, M.M.H. Mansour, S.C. Kazmierczak, Nanodiagnostics: A new frontier for clinical laboratory medicine. Clin. Chem. (Washington, D. C., 2006), 52, 1238

    Google Scholar 

  34. M. Brehm, T. Taubner, R. Hillenbrand, F. Keilmann, Infrared spectroscopic mapping of single nanoparticles and viruses at nanoscale resolution. Nano. Lett. 6, 1307 (2006)

    Article  CAS  Google Scholar 

  35. M. Breunig, S. Bauer, A. Goepferich, Polymers and nanoparticles: intelligent tools for intra cellular targeting. Eur. J. Pharm. Biopharm. 68, 112 (2008)

    Article  CAS  Google Scholar 

  36. W. Jiang, B.Y.S. Kim, J.T. Rutka, W.C.W. Chan, Nanoparticle-mediated cellular response is size-dependent. Nat. Nanotech. 3, 145 (2008)

    Article  CAS  Google Scholar 

  37. D.A. Egas, M.J. Wirth, Fundamentals of protein separations: 50 years of nanotechnology, and growing. Annu. Rev. Anal. Chem. 1, 833 (2008)

    Article  CAS  Google Scholar 

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Acknowledgments

The work was principally supported by Science Foundation Ireland (SFI) under the Principal Investigator Programme Contract No. 06/IN.1/I85. Institutional funding from INSPIRE is further acknowledged. A. Sanyal acknowledges the Irish Research Council for Science, Engineering and Technology (IRCSET) for a research postdoctoral fellowship. The authors thank Professor Noel Buckley for access to Hitachi S-4800 HRSEM. Dr Gordon Armstrong is also acknowledged for help in optical measurements.

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Correspondence to Ambarish Sanyal .

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Sanyal, A., Ryan, K.M. (2013). Water Dispersible Semiconductor Nanorod Assemblies Via a Facile Phase Transfer and Their Application as Fluorescent Biomarkers. In: Giri, P.K., Goswami, D.K., Perumal, A. (eds) Advanced Nanomaterials and Nanotechnology. Springer Proceedings in Physics, vol 143. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34216-5_9

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