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Principal Component Analysis for Bacterial Proteomic Analysis

  • Y. -h. Taguchi
  • Akira Okamoto
Part of the Lecture Notes in Computer Science book series (LNCS, volume 7632)

Abstract

Proteomic analysis is a very useful procedure to understand the bacterial behavioural responses to the external environmental factors. This is because bacterial genome information is mainly devoted to code enzyme for the control of the cellular metabolic networks. In this paper, we have performed proteomic analysis of Streptococcus pyogenes, which is known to be flesh-eating bacteria and can cause several human life-threatening diseases. Its proteome during growth phase is measured for four time points under two different culture conditions; with or without shaking. Its purpose is to understand the adaptivity to oxidative stresses. Principal component analysis is applied and turns out to be useful to depict biologically important proteins for both supernatant and cell components.

Keywords

Streptococcus pyogenes proteomic analysis principal component analysis 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Y. -h. Taguchi
    • 1
  • Akira Okamoto
    • 2
  1. 1.Department of PhysicsChuo UniversityBunkyo-kuJapan
  2. 2.Department of School Nursing and HealthAichi University of EducationKariyaJapan

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