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Total Synthesis of Natural Products pp 39–65Cite as

The Kinamycins

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Abstract

Chemists are continuously confronted with the challenge of classifying and accurately assessing the complexity elements presented by natural products, and these elements are often assigned familiar categories such as topological, stereochemical, and size complexities. An interesting additional element of complexity involves the fusion of well-known functional groups into larger entities, with the individual constituents in communication by a combination of resonance and inductive effects. α,β-Unsaturated carbonyls (carbonyl + alkene) and enamines (amine + alkene) may be the simplest examples of such functionality.

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Author information

Authors and Affiliations

  1. Yale University, 225 Prospect Street, New Haven, CT, 06520-8107, USA

    Seth B. Herzon

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  1. Seth B. Herzon
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Editors and Affiliations

  1. Firestone Court 3, Skillman, 08558, New Jersey, USA

    Jie Jack Li

  2. , Dept. of Chemistry and Chemical Biology, Harvard University, Oxford Street 12, Cambridge, 02138, USA

    E.J. Corey

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© 2012 Springer-Verlag Berlin Heidelberg

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Herzon, S.B. (2012). The Kinamycins. In: Li, J., Corey, E. (eds) Total Synthesis of Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34065-9_3

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