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Chaos and Complex Systems pp 95–103Cite as

A New Rule-Based System for the Construction and Structural Characterization of Artificial Proteins

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Abstract

In this paper, we present a new rule-based system for an artificial protein design incorporating ternary amino acid polarity (polar, nonpolar, and neutral). It may be used to design de novo α and β protein fold structures and mixed class proteins. The targeted molecules are artificial proteins with important industrial and biomedical applications, related to the development of diagnostic-therapeutic peptide pharmaceuticals, antibody mimetics, peptide vaccines, new nanobiomaterials and engineered protein scaffolds.

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Acknowledgements

The support of the Croatian Ministry of Science, Education and Sports is gratefully acknowledged (grant No. 098–0982929–2524).

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Authors and Affiliations

  1. Ruđer Bošković Institute, Bijenička cesta 54, 10000, Zagreb, Croatia

    Nikola Štambuk & Paško Konjevoda

  2. Department of Radiology, General Hospital Požega, Osječka 105, 34000, Požega, Croatia

    Nikola Gotovac

Authors
  1. Nikola Štambuk
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  2. Paško Konjevoda
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  3. Nikola Gotovac
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Corresponding author

Correspondence to Nikola Štambuk .

Editor information

Editors and Affiliations

  1. Physics Department, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Stavros G. Stavrinides

  2. Institute for Mathematical Research, Serdang, Malaysia

    Santo Banerjee

  3. Department of Mathematics - Computer, Istanbul Kultur Unviversity, Istanbul, Turkey

    Suleyman Hikmet Caglar

  4. Department of Physics, Istanbul Kultur University, Istanbul, Turkey

    Mehmet Ozer

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Štambuk, N., Konjevoda, P., Gotovac, N. (2013). A New Rule-Based System for the Construction and Structural Characterization of Artificial Proteins. In: Stavrinides, S., Banerjee, S., Caglar, S., Ozer, M. (eds) Chaos and Complex Systems. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-33914-1_12

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  • DOI: https://doi.org/10.1007/978-3-642-33914-1_12

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-33913-4

  • Online ISBN: 978-3-642-33914-1

  • eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)

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