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Effect of Piriformospora indica on Enhanced Biosynthesis of Anticancer Drug, Podophyllotoxin, in Plant Cell Cultures of Linum album

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Piriformospora indica

Part of the book series: Soil Biology ((SOILBIOL,volume 33))

Abstract

Plant cell technology provides an alternative to the whole plant cultivation for the production of valuable plant-based secondary metabolites. The treatment of plant cells with elicitors is one of the most effective strategies for improving secondary metabolite production by plant tissue and cell cultures. These elicitors stimulate secondary metabolite production and thereby decrease the process time to attain high product concentrations. A variety of fungal products (cell wall polysaccharides, culture filtrate, mycelia, spores, polypeptides, glycoproteins, lipid molecules, and metabolites) have been used as elicitors to trigger secondary metabolite biosynthesis by plant cell cultures. This chapter provides information about effects of culture filtrate, cell extract, and live cells of root endophytic fungus Piriformospora indica as elicitors, on growth and lignan production by Linum album hairy root cultures.

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Authors and Affiliations

  1. Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110 016, India

    Vinod Kumar, Vikram Sahai & V. S. Bisaria

  2. Department of Chemical and Biomolecular Engineering, Laboratory of Metabolic Engineering of Microorganisms, Pusan National University, Busan, 609735, South Korea

    Vinod Kumar

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  2. Vikram Sahai
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  3. V. S. Bisaria
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Correspondence to V. S. Bisaria .

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Editors and Affiliations

  1. Amity Institute of Microbial Technology, Amity University Uttar Pradesh, E-3 Block, Sector 125, Noida, 201303, Uttar Pradesh, India

    Ajit Varma

  2. , FB Biology, Systematic Botany & Mycology, Philipps University of Marburg, Karl von Frisch Str. 8, Marburg, 35032, Germany

    Gerhard Kost

  3. Inst. Allgemeine Botanik, LS Pflanzenphysiologie, Univ. Jena, Dornburger Str. 159, Jena, 07743, Thüringen, Germany

    Ralf Oelmüller

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Kumar, V., Sahai, V., Bisaria, V.S. (2013). Effect of Piriformospora indica on Enhanced Biosynthesis of Anticancer Drug, Podophyllotoxin, in Plant Cell Cultures of Linum album . In: Varma, A., Kost, G., Oelmüller, R. (eds) Piriformospora indica. Soil Biology, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-33802-1_7

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