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Applications of Cyclic β-Glucans

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Cyclic β-Glucans from Microorganisms

Part of the book series: SpringerBriefs in Microbiology ((BRIEFSMICROBIOL))

Abstract

Cyclic glucans have larger inner cavity diameter (~0.88 nm) when compared to those found in cyclodextrins (~0.85 nm). This property is valuable in pharmaceutical and food industries. They are used as wound dressing material and for the synthesis of nanowire. Cyclic β-glucans are used as inclusion agents for drugs, including indomethacin, ergosterol, vitamin D3, vitamin E, vitamin KI, propericiazine, reserpine, fluorescein, and flavones. β-(1,3)-(1,6) cyclic glucans have antitumorigenic and immunostimulating activity. They bind to the dectin-1 receptor of macrophages and stimulate immunogenicity. They are used as solubility enhancers for drugs, including zearalenone, paclitaxel, and naproxen. Linear β-(1,3)-glucan is used as one-dimensional host for the synthesis of water-soluble single-walled carbon nanotubes.

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  1. Department of Biotechnology, Indian Institute of Technology-Madras, Chennai, 600036, India

    Geetha Venkatachalam, Sathyanarayana Gummadi & Mukesh Doble

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  1. Geetha Venkatachalam
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  2. Sathyanarayana Gummadi
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  3. Mukesh Doble
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Venkatachalam, G., Gummadi, S., Doble, M. (2013). Applications of Cyclic β-Glucans. In: Cyclic β-Glucans from Microorganisms. SpringerBriefs in Microbiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32995-1_2

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