Abstract
Compared with the first synthesis of triptycene in 1942 [Bartlett et al. in J Am Chem Soc 64(11):2649–2653, 1942], it was not until 32 years later that Skvarche and Shalaev [Dokl Akad Nauk SSSR 216(1):110–112, 1974] first accomplished the synthesis of pentiptycene (2). As shown in Scheme 3.1, pentiptycene 2 was synthesized in about 10 % total yield by a three-step route starting from 2-aminotriptycene 1. Similar to the way for the synthesis of triptycene, the Diels–Alder reaction between anthracene and benzyne was also the key process to pentiptycene.
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Chen, CF., Ma, YX. (2013). Synthesis and Reactions of Pentiptycenes and Their Derivatives. In: Iptycenes Chemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32888-6_3
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DOI: https://doi.org/10.1007/978-3-642-32888-6_3
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