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Applied Cross-Coupling Reactions

Part of the book series: Lecture Notes in Chemistry ((LNC,volume 80))

Abstract

This chapter describes the design and development of biologically active compounds using cross-coupling reactions as key steps. These biologically active compounds are of both academic and industrial importance. Drug candidates can be prepared from easily available substrates in a few steps through cross-coupling—underscoring the versatility, effectiveness, functional group tolerance, and mild reaction conditions of the cross-coupling methods. Due to these advantages, palladium-catalyzed cross-coupling reactions are being utilized in the industrial production of pharmaceuticals.

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Authors and Affiliations

  1. Division of Earth, Life, and Molecular Sciences, Graduate School of Natural Science and Technology Okayama University, 3-1-1 Tsushimanaka.Kita-ku, Okayama, 700-8530, Japan

    Jiao Jiao & Yasushi Nishihara

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  1. Jiao Jiao
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  2. Yasushi Nishihara
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Correspondence to Yasushi Nishihara .

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  1. Department of Chemistry, Okayama University, Okayama, Japan

    Yasushi Nishihara

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Jiao, J., Nishihara, Y. (2013). Pharmaceuticals. In: Nishihara, Y. (eds) Applied Cross-Coupling Reactions. Lecture Notes in Chemistry, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32368-3_4

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