Skip to main content
SpringerLink
Log in

Cutometer®

  • Chapter
  • First Online:
Book cover Non Invasive Diagnostic Techniques in Clinical Dermatology

Abstract

The human skin possesses a complex structure and various functions which ensure the entity between the organism and the environment. Mechanical properties of the skin are of major importance for its protective function. They vary in accordance with age, sex and body sites, in some physiological and pathological skin conditions, and change due to different external and therapeutic influences. Considerable progress in the quantification of the skin mechanical functions had been achieved for the past 20 years through the introduction of modern non-invasive bioengineering methods and devices which provide the researchers with objective, quantitative, sensitive and reproducible measurements in vivo.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Akhtar N, Zaman SU, Khan BA, Amir MN, Ebrahimzadeh MA (2011) Calendula extract: effects on mechanical parameters of human skin. Acta Pol Pharm 68(5):693–701

    PubMed  Google Scholar 

  2. Andres C, Kollmar A, Mempel M, Hein R, Ring J, Eberlein B (2010) Successful ultraviolet A1 phototherapy in the treatment of localized scleroderma: a retrospective and prospective. Br J Dermatol 162(2):445–447, Epub 2009 Aug 8

    Article  PubMed  CAS  Google Scholar 

  3. Auriol F, Vaillant L, Machet L, Diridollou S, Lorette G (1993) Effects of short-time hydration on skin extensibility. Acta Derm Venereol 73(5):344–347

    PubMed  CAS  Google Scholar 

  4. Auriol F, Vaillant L, Pelucio-Lopes C, Machet L, Diridollou S, Berson M, Lorette G (1994) Study of cutaneous extensibility in lymphoedema of the lower limbs. Br J Dermatol 131(2):265–269

    Article  PubMed  CAS  Google Scholar 

  5. Barel AO, Lambrecht R, Clarys P (1998) Mechanical function of the skin: state of the art. In: Elsner P, Barel AO, Berardesca E, Gabard B, Serup J (eds) Skin bioengineering. Techniques and applications in dermatology and cosmetology, vol 26. Karger, Basel, pp 69–83, Curr Probl Dermatol

    Google Scholar 

  6. Barel AO (2002) Product testing: moisturizers. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Skin biomechanics. CRC Press, Boca Raton, pp 241–256

    Google Scholar 

  7. Barel AO, Courage W, Clarys P (2006) Suction chamber method for measurement of skin mechanics: the new digital version of the cutometer. In: Serup J, Jemec GBE, Grove G (eds) Handbook of non-invasive methods and the skin. CRC Taylor & Francis, Boca Raton, pp 583–591

    Chapter  Google Scholar 

  8. Berardesca E, Gabba P, Farinelli N, Borroni G, Rabbiosi G (1990) In vivo tretinoin-induced changes in skin mechanical properties. Br J Dermatol 122(4):525–529

    Article  PubMed  CAS  Google Scholar 

  9. Berndt U, Elsner P (2002) Hardware and measuring principle: the cutometer. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Bioengineering and the skin. Skin biomechanics. CRC Press, Boca Raton, pp 91–97

    Google Scholar 

  10. Braham C, Betea D, Piйrard-Franchimont C, Beckers A, Piйrard GE (2002) Skin tensile properties in patients treated for acromegaly. Dermatology 204(4):325–329

    Article  PubMed  Google Scholar 

  11. Brandi C, D’Aniello C, Grimaldi L, Caiazzo E, Stanghellini E (2004) Carbon dioxide therapy: effects on skin irregularity and its use as a complement to liposuction. Aesthetic Plast Surg 28(4):222–225

    Article  PubMed  Google Scholar 

  12. Cua AB, Wilhelm KP, Maibach HI (1990) Elastic properties of human skin: relation to age, sex, and anatomical region. Arch Dermatol Res 282(5):283–288

    Article  PubMed  CAS  Google Scholar 

  13. Deleixhe-Mauhin F, Piйrard-Franchimont C, Rorive G, Piйrard GE (1994) Influence of chronic haemodialysis on the mechanical properties of skin. Clin Exp Dermatol 19(2):130–133

    Article  PubMed  CAS  Google Scholar 

  14. de Rie MA, Enomoto DN, de Vries HJ, Bos JD (2003) Evaluation of medium-dose UVA1 phototherapy in localized scleroderma with the cutometer and fast Fourier transform method. Dermatology 207(3):298–301

    Article  PubMed  Google Scholar 

  15. Distante F, Pagani V, Bonfigli A, Rigano L, Fluhr J (2007) Objective evaluation of the placebo effect in cosmetic treatments. A randomized controlled study. Int J Cosmet Sci 29:64

    Article  Google Scholar 

  16. Dobrev H (1996) In vivo noninvasive study of the mechanical properties of the human skin after single application of topical corticosteroids. Folia Med (Plovdiv) 38(2):11–17

    CAS  Google Scholar 

  17. Dobrev H (1998) In vivo study of skin mechanical properties in scleredema of Buschke. Acta Derm Venereol 78(2):103–106

    Article  PubMed  CAS  Google Scholar 

  18. Dobrev H (1998) Use of cutometer to assess dermal oedema in erysipelas of the lower legs. Skin Res Technol 4(3):155–159

    Article  Google Scholar 

  19. Dobrev HP (1999) In vivo study of skin mechanical properties in patients with systemic sclerosis. J Am Acad Dermatol 40(3):436–442

    Article  PubMed  CAS  Google Scholar 

  20. Dobrev H (1999) Non-invasive monitoring of the mechanical properties of keloids during cryosurgery. Acta Derm Venereol 79(6):487–488

    Article  PubMed  CAS  Google Scholar 

  21. Dobrev H (1999) Age related changes in the mechanical properties of human skin. Dermatol Venereol (Bulgaria) 38(2):21–25

    Google Scholar 

  22. Dobrev H (2000) Photoaging and skin elasticity. Research Reports of the Union of Scientists in Bulgaria – Plovdiv. Annual, Series B. Nat Sci Humanit 1:117–120

    Google Scholar 

  23. Dobrev H (2000) Influence of telegammatherapy on the skin physiology. In: 7the national congress of dermatology and venereology, Sofia, 11–13 May 2000. pp 28 (Abstract)

    Google Scholar 

  24. Dobrev H (2000) In vivo study of skin mechanical properties in psoriasis vulgaris. Acta Derm Venereol 80(4):263–266

    Article  PubMed  CAS  Google Scholar 

  25. Dobrev H (2000) Use of cutometer to assess epidermal hydration. Skin Res Technol 6(4):239–244

    Article  PubMed  Google Scholar 

  26. Dobrev H (2000) Value of non-invasive bioengineering investigation of the skin mechanical properties in vivo. Doctoral thesis, Plovdiv

    Google Scholar 

  27. Dobrev H (2001) Syndrome Ehlers-Danlos – mechanical properties of the skin. In: 10th annual Sofia dermatological days, vol 40(2). Sofia, 2–3 Nov 2001, p 27. Dermatol Venereol (Bulgaria) (Summary)

    Google Scholar 

  28. Dobrev H. (2001) Fasciitis eosinophilica – mechanical properties of the skin. In: 10th annual Sofia dermatological days, vol 40(2), Sofia, 2–3 Nov 2001, p 28. Dermatol Venereol (Bulgaria) (Summary)

    Google Scholar 

  29. Dobrev H (2001) Evaluation of the inhibitory activity of topical indomethacin, betamethasone valerate and emollients on UVL-induced inflammation by means of non-invasive measurements of the skin elasticity. Photodermatol Photoimmunol Photomed 17(4):184–188

    Article  PubMed  CAS  Google Scholar 

  30. Dobrev HP (2002) A study of human skin mechanical properties by means of cutometer. Folia Med (Plovdiv) 44(3):5–10

    Google Scholar 

  31. Dobrev H (2002) Treatment of psoriasis vulgaris with hydrocolloid occlusive dressings in combination with betamethasone dipropionate 0.05% cream. Scientific Researches of the Union of Scientists – Plovdiv. Series D Medicine. Pharm Stomatol 1:103–106

    Google Scholar 

  32. Dobrev H (2002) Mechanical properties in other dermatological diseases. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Skin biomechanics. CRC Press, Boca Raton, pp 215–228

    Google Scholar 

  33. Dobrev H (2005) Application of cutometer area parameters for the study of human skin fatigue. Skin Res Technol 11(2):120–122

    Article  PubMed  Google Scholar 

  34. Dobrev H (2005) The effects of topically applied Matrixyl, natural grape seed and avocado oils on skin surface, hydration and elasticity. III. Spring symposium of the European Academy of Dermatology & Venereology (EADV), Sofia, 19–22 May 2005. Book of Abstracts: p 73

    Google Scholar 

  35. Dobrev H (2005) Evaluation of the efficacy of a Rooibos extract containing anti-wrinkle cream. III. Spring symposium of the European Academy of Dermatology & Venereology (EADV), Sofia, 19–22 May 2005. Book of Abstracts: p 84

    Google Scholar 

  36. Dobrev H (2007) In vivo study of skin mechanical properties in Raynaud’s phenomenon. Skin Res Technol 13(1):91–94

    Article  PubMed  Google Scholar 

  37. Dobrev H. (2008) Evaluation of therapy effect in patients with eczema by measuring of water content and mechanical properties of lesional skin. In: VIII national congress of the Bulgarian Dermatological Society with international participation, Albena, 2–5 Oct 2008 (Poster 25)

    Google Scholar 

  38. Dobrev H (2009) How do cosmetics improve the skin mechanical properties? In: 18th congress of the European Academy of Dermatology & Venereology (EADV), Berlin, 7–11 Oct 2009.. J Eur Acad Dermatol Venerol (Suppl.)

    Google Scholar 

  39. Draaijers LJ, Botman YA, Tempelman FR, Kreis RW, Middelkoop E, van Zuijlen PP (2004) Skin elasticity meter or subjective evaluation in scars: a reliability assessment. Burns 30(2):109–114

    Article  PubMed  Google Scholar 

  40. Elsner P (1995) Skin elasticity. In: Berardesca E, Elsner P, Wilhelm K-P, Maibach HI (eds) Bioengineering of the skin: methods and instrumentation. CRC Press, Boca Raton, pp 53–64

    Google Scholar 

  41. Elsner P, Wilhelm D, Maibach HI (1990) Mechanical properties of human forearm and vulvar skin. Br J Dermatol 122(5):607–614

    Article  PubMed  CAS  Google Scholar 

  42. Enomoto DNH, Mekkes JR, Bossuyt PMM, Hoekzema R, Bos JD (1996) Quantification of cutaneous sclerosis with a skin elasticity meter in patients with generalized scleroderma. J Am Acad Dermatol 35:381–387

    Article  PubMed  CAS  Google Scholar 

  43. Flagothier C, Goffin V, Hermanns-Lк T, Piйrard GE, Quatresooz P (2007) A four-generation Ehlers-Danlos syndrome with vascular dissections. Skin ultrastructure and biomechanical properties. J Med Eng Technol 31(3):175–180

    Article  PubMed  CAS  Google Scholar 

  44. Fong SS, Hung LK, Cheng JC (1997) The cutometer and ultrasonography in the assessment of postburn hypertrophic scar–a preliminary study. Burns 23(Suppl 1):S12–S18

    Article  PubMed  Google Scholar 

  45. Grudeva-Popova J, Dobrev H (2000) Biomechanical measurement of skin distensibility in scleredema of Buschke associated with multiple myeloma. Clin Exp Dermatol 25(3):247–249

    Article  PubMed  CAS  Google Scholar 

  46. Heinrich U, Garbe B, Tronnier H (2007) In vivo assessment of Ectoin: a randomized, vehicle-controlled clinical trial. Skin Pharmacol Physiol 20(4):211–218, Epub 2007 May 23

    Article  PubMed  CAS  Google Scholar 

  47. Hashmi F, Malone-Lee J, Hounsell E (2006) Plantar skin in type II diabetes: an investigation of protein glycation and biomechanical properties of plantar epidermis. Eur J Dermatol 16(1):23–32

    PubMed  CAS  Google Scholar 

  48. Hashmi F, Malone-Lee J (2007) Measurement of skin elasticity on the foot. Skin Res Technol 13(3):252–258

    Article  PubMed  Google Scholar 

  49. Henry F, Van Look R, Goffin V, Fissette J, Pierard GE (1996) Mechanical properties of skin and liposuction. Dermatol Surg 22(6):566–568

    Article  PubMed  CAS  Google Scholar 

  50. Henry F, Goffin V, Piйrard-Franchimont C, Piйrard GE (1996) Mechanical properties of skin in Ehlers-Danlos syndrome, types I, II, and III. Pediatr Dermatol 13(6):464–467

    Article  PubMed  CAS  Google Scholar 

  51. Henry F, Piйrard-Franchimont C, Cauwenbergh G, Piйrard GE (1997) Age-related changes in facial skin contours and rheology. J Am Geriatr Soc 45(2):220–222

    PubMed  CAS  Google Scholar 

  52. Henry F, Piйrard-Franchimont C, Pans A, Piйrard GE (1997) Striae distensae of pregnancy. An in vivo biomechanical evaluation. Int J Dermatol 36(7):506–508

    Article  PubMed  CAS  Google Scholar 

  53. Ishikawa T, Ishikawa O, Miyachi Y (1995) Measurement of skin elastic properties with a new suction device (I): relationship to age, sex and the degree of obesity in normal individuals. J Dermatol 22(10):713–717

    PubMed  CAS  Google Scholar 

  54. Ishikawa T, Tamura T (1996) Measurement of skin elastic properties with a new suction device (II): systemic sclerosis. J Dermatol 23(3):165–168

    PubMed  CAS  Google Scholar 

  55. Kapoor S, Saraf S (2010) Assessment of viscoelasticity and hydration effect of herbal moisturizers using bioengineering techniques. Pharmacogn Mag 6(24):298–304

    Article  PubMed  CAS  Google Scholar 

  56. Khazaka D (2010) Information and operating instructions for the cutometer® MPA 580 and the software cutometer® MPA Q. Courage + Khazaka Electronic GmbH, Cologne

    Google Scholar 

  57. Koch RJ, Cheng ET (1999) Quantification of skin elasticity changes associated with pulsed carbon dioxide laser skin resurfacing. Arch Facial Plast Surg 1(4):272–275

    Article  PubMed  CAS  Google Scholar 

  58. Krueger N, Luebberding S, Oltmer M, Streker M, Kerscher M (2011) Age-related changes in skin mechanical properties: a quantitative evaluation of 120 female subjects. Skin Res Technol 17(2):141–148

    Article  PubMed  Google Scholar 

  59. Krusche T, Worret WI (1995) Mechanical properties of keloids in vivo during treatment with intralesional triamcinolone acetonide. Arch Dermatol Res 287(3–4):289–293

    Article  PubMed  CAS  Google Scholar 

  60. Manosroi A, Chutoprapat R, Abe M, Manosroi W, Manosroi J (2012) Anti-aging efficacy of topical formulations containing niosomes entrapped with rice bran bioactive compounds. Pharm Biol 50(2):208–224

    Article  PubMed  CAS  Google Scholar 

  61. Manuskiatti W, Wachirakaphan C, Lektrakul N, Varothai S (2009) Circumference reduction and cellulite treatment with a TriPollar radiofrequency device: a pilot study. J Eur Acad Dermatol Venereol 23(7):820–827, Epub 2009 Apr 8

    Article  PubMed  CAS  Google Scholar 

  62. Marini A, Grether-Beck S, Jaenicke T, Weber M, Burki C, Formann P, Brenden H, Schцnlau F, Krutmann J (2012) Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women. Skin Pharmacol Physiol 25(2):86–92, Epub 2012 Jan 21

    Article  PubMed  CAS  Google Scholar 

  63. McCall-Perez F, Stephens TJ, Herndon JH Jr (2011) Efficacy and tolerability of a facial serum for fine lines, wrinkles, and photodamaged skin. J Clin Aesthet Dermatol 4(7):51–54

    PubMed  Google Scholar 

  64. Mimoun N, Razzouq N, Wolkenstein P, Moreno JC, Marty JP, Lantieri L, Astier A, Paul M (2006) Evaluation of skin viscoelasticity in type 1 neurofibromatosis patients. Skin Pharmacol Physiol 19(1):22–27, Epub 2005 Oct 20

    Article  PubMed  CAS  Google Scholar 

  65. Murray BC, Wickett RR (1996) Sensitivity of cutometer data to stratum corneum hydration level. A preliminary study. Skin Res Technol 2:167–172

    Article  Google Scholar 

  66. Nedelec B, Correa JA, Rachelska G, Armour A, LaSalle L (2008) Quantitative measurement of hypertrophic scar: intrarater reliability, sensitivity, and specificity. J Burn Care Res 29(3):489–500

    Article  PubMed  Google Scholar 

  67. Nedelec B, Correa JA, Rachelska G, Armour A, LaSalle L (2008) Quantitative measurement of hypertrophic scar: interrater reliability and concurrent validity. J Burn Care Res 29(3):501–511

    Article  PubMed  Google Scholar 

  68. Nikkels-Tassoudji N, Henry F, Letawe C, Pierard-Franchimont C, Lefebvre P, Pierard GE (1996) Mechanical properties of the diabetic waxy skin. Dermatology 192(1):19–22

    Article  PubMed  CAS  Google Scholar 

  69. Nikkels-Tassoudji N, Henry F, Piйrard-Franchimont C, Piйrard GE (1996) Computerized evaluation of skin stiffening in scleroderma. Eur J Clin Invest 26(6):457–460

    Article  PubMed  CAS  Google Scholar 

  70. O’Goshi K (2006) Suction chamber method for measurement of skin mechanics: the cutometer. In: Serup J, Jemec GBE, Grove G (eds) Handbook of non-invasive methods and the skin. CRC Taylor & Francis, Boca Raton, pp 579–582

    Chapter  Google Scholar 

  71. Ono I (2011) A study on the alterations in skin viscoelasticity before and after an intradermal administration of growth factor. J Cutan Aesthet Surg 4(2):98–104

    Article  PubMed  Google Scholar 

  72. Pans A, Pierard GE, Albert A, Desaive C (1997) Adult groin hernias: new insight into their biomechanical characteristics. Eur J Clin Invest 27(10):863–868

    Article  PubMed  CAS  Google Scholar 

  73. Park JW, Seo CH, Han SH, Lee YG (2011) Sympathetic influence on biomechanical skin properties after spinal cord injury. Spinal Cord 49(2):236–243, Epub 2010 Sep 21

    Article  PubMed  CAS  Google Scholar 

  74. Piйrard GE, Nikkels-Tassoudji N, Piйrard-Franchimont C (1995) Influence of the test area on the mechanical properties of skin. Dermatology 191(1):9–15

    Article  Google Scholar 

  75. Piйrard GE, Letawe C, Dowlati A, Piйrard-Franchimont C (1995) Effect of hormone replacement therapy for menopause on the mechanical properties of skin. J Am Geriatr Soc 43(6):662–665

    Google Scholar 

  76. Piйrard GE, Henry F, Piйrard-Franchimont C (1996) Comparative effect of short-term topical tretinoin and glycolic acid on mechanical properties of photodamaged facial skin in HRT-treated menopausal women. Maturitas 23(3):273–277

    Article  Google Scholar 

  77. Piйrard GE, Nizet JL, Adant JP, Camacho MA, Pans A, Fissette J (1999) Tensile properties of relaxed excised skin exhibiting striae distensae. J Med Eng Technol 23(2):69–72

    Article  Google Scholar 

  78. Piйrard GE, Vanderplaetsen S, Piйrard-Franchimont C (2001) Comparative effect of hormone replacement therapy on bone mass density and skin tensile properties. Maturitas 40(3):221–227

    Article  Google Scholar 

  79. Piйrard-Franchimont C, Henry F, Crielaard JM, Piйrard GE (1996) Mechanical properties of skin in recombinant human growth factor abusers among adult bodybuilders. Dermatology 192(4):389–392

    Article  Google Scholar 

  80. Piйrard-Franchimont C, Nikkels-Tassoudji N, Lefиbvre P, Piйrard GE (1998) Subclinical skin stiffening in adults suffering from type 1 diabetes mellitus. A comparison with Raynaud’s syndrome. J Med Eng Technol 22(5):206–210

    Article  Google Scholar 

  81. Piйrard-Franchimont C, Letawe C, Fumal I, Van Cromphaut I, Piйrard GE (1998) Gravitational syndrome and tensile properties of skin in the elderly. Dermatology 197(4):317–320

    Article  Google Scholar 

  82. Piйrard-Franchimont C, Cornil F, Dehavay J, Deleixhe-Mauhin F, Letot B, Piйrard GE (1999) Climacteric skin ageing of the face–a prospective longitudinal comparative trial on the effect of oral hormone replacement therapy. Maturitas 32(2):87–93

    Article  Google Scholar 

  83. Qu D, Masotti CJ, Seehra GP (2007) Effect of age and gender on the viscoelastic properties of skin. J Soc Cosmet Chem 58(2):197–198

    Google Scholar 

  84. Rennekampff HO, Rabbels J, Reinhard V, Becker ST, Schaller HE (2006) Comparing the Vancouver scar scale with the cutometer in the assessment of donor site wounds treated with various dressings in a randomized trial. J Burn Care Res 27(3):345–351

    Article  PubMed  Google Scholar 

  85. Reuther T, Bayrhammer J, Kerscher M (2010) Effects of a three-session skin rejuvenation treatment using stabilized hyaluronic acid-based gel of non-animal origin on skin elasticity: a pilot study. Arch Dermatol Res 302(1):37–45

    Article  PubMed  Google Scholar 

  86. Romano C, Rubegni P, De Aloe G, Stanghellini E, D’Ascenzo G, Andreassi L, Fimiani M (2003) Extracorporeal photochemotherapy in the treatment of eosinophilic fasciitis. J Eur Acad Dermatol Venereol 17(1):10–13

    Article  PubMed  CAS  Google Scholar 

  87. Ryu HS, Joo YH, Kim SO, Park KC, Youn SW (2008) Influence of age and regional differences on skin elasticity as measured by the cutometer. Skin Res Technol 14(3):354–358

    Article  PubMed  Google Scholar 

  88. Saraf S, Jeswani G, Deep Kaur C, Saraf S (2011) Development of novel herbal cosmetic cream with curcuma longa extract loaded transfersomes for antiwrinkle effect. Afr J Pharm Pharmacol 5(8):1054–1062

    Google Scholar 

  89. Segger D, Schцnlau F (2004) Supplementation with Evelle improves skin smoothness and elasticity in a double-blind, placebo-controlled study with 62 women. J Dermatolog Treat 15(4):222–226

    Article  PubMed  CAS  Google Scholar 

  90. Serup J (2002) Mechanical properties of human skin: elasticity parameters and their relevance. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Bioengineering and the skin. Skin biomechanics. CRC Press, Boca Raton, pp 41–47

    Google Scholar 

  91. Sнn P, Stupka I, Brychta P (2010) Evaluation and comparison of composite and split-thickness skin grafts using cutometer mpa 580. Ann Burns Fire Disaster 23(4):208–213

    Google Scholar 

  92. Soyun C, Chong-Won C, Chong-Hyun W, Dong HL, Kwang HC, Chung JH (2006) Dietary bee pollen supplementation does not improve signs of photoaging in human skin in vivo. Korean J Invest Dermatol 13(4):120–124

    Google Scholar 

  93. Sumino H, Ichikawa S, Abe M, Endo Y, Ishikawa O, Kurabayashi M (2004) Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity in women. J Am Geriatr Soc 52(6):945–949

    Article  PubMed  Google Scholar 

  94. Takema Y, Yorimoto Y, Kawai M, Imokawa G (1994) Age-related changes in the elastic properties and thickness of human facial skin. Br J Dermatol 131(5):641–648

    Article  PubMed  CAS  Google Scholar 

  95. Tronnier H, Wiebusch M, Heinrich U (2008) Change in skin physiological parameters in space–report on and results of the first study on man. Skin Pharmacol Physiol 21(5):283–292, Epub 2008 Jul 28

    Article  PubMed  CAS  Google Scholar 

  96. Yoon HS, Baik SH, Oh CH (2002) Quantitative measurement of desquamation and skin elasticity in diabetic patients. Skin Res Technol 8(4):250–254

    Article  PubMed  Google Scholar 

  97. van Zuijlen PP, van Trier AJ, Vloemans JF, Groenevelt F, Kreis RW, Middelkoop E (2000) Graft survival and effectiveness of dermal substitution in burns and reconstructive surgery in a one-stage grafting model. Plast Reconstr Surg 106(3):615–623

    PubMed  Google Scholar 

  98. Wanitphakdeedecha R, Eimpunth S, Manuskiatti W (2011) The effects of mucopolysaccharide polysulphate on hydration and elasticity of human skin. Dermatol Res Pract 2011:807906, Epub 2011 Jun 30

    PubMed  Google Scholar 

  99. Wickett RR (2002) Standardization of skin biomechanical measurements. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Bioengineering and the skin. Skin biomechanics. CRC Press, Boca Raton, pp 179–185

    Google Scholar 

  100. Wilhelm K-P, Maibach HI (2002) Mapping mechanical properties of human skin. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Skin biomechanics. CRC Press, Boca Raton, pp 187–197

    Google Scholar 

  101. Worret W-I (2002) Antikeloidal products. In: Elsner P, Berardesca E, Wilhelm K-P, Maibach HI (eds) Bioengineering and the skin. Skin biomechanics. CRC Press, Boca Raton, pp 257–268

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Clinic of Dermatology and Venereology, University Hospital “St. George”, 15A V. Aprilov St., 4002, Plovdiv, Bulgaria

    Hristo Dobrev MD, PhD

  2. Department of Dermatology and Venereology, Medical University, Plovdiv, Bulgaria

    Hristo Dobrev MD, PhD

Authors
  1. Hristo Dobrev MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hristo Dobrev MD, PhD .

Editor information

Editors and Affiliations

  1. Clinical Dermatology, San Gallicano Dermatological Institute, Rome, Roma, Italy

    Enzo Berardesca

  2. Dermatology, University of California San Francisco, San Francisco, CA, California, USA

    Howard I. Maibach

  3. Proderm, Schenefeld/Hamburg, Germany

    Klaus-Peter Wilhelm

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Berlin Heidelberg

About this chapter

Cite this chapter

Dobrev, H. (2014). Cutometer®. In: Berardesca, E., Maibach, H., Wilhelm, KP. (eds) Non Invasive Diagnostic Techniques in Clinical Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32109-2_29

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-32109-2_29

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-32108-5

  • Online ISBN: 978-3-642-32109-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation