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Prospective Studies on Mite (Dermatophagoides farinae) Allergen Immunotherapy in China

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Multidisciplinary Approaches to Allergies

Part of the book series: Advanced Topics in Science and Technology in China ((ATSTC))

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Abstract

Mite allergy study was founded in China beginning in the 1970s and conducted at Shanghai First Medical College. The highest allergenic contents had been detected in comparing the results with those of foreign literature. Around 80% of allergic cases were sensitive to mite allergen by the skin prick tests in concordance with the nasal provocation test and sIgE assay results. Seasonal classic immunotherapy for allergic patients by product Injectio Dermatophagoidei Farinae, the only commercial allergen licensed by the Chinese government, achieved very good results in improving symptoms of allergic disorder in a majority of the cases, in addition, long-lasting effects of mite immunotherapy was also certified with minimal adverse reactions. Studies on sublingual mite vaccine for mite allergic disorders have been synchronized with identified foreign trends since 1992. Sublingual drops are further acceptable for children’s cases almost without age restriction with a high efficacy rate. It has also been shown that rush mite immunotherapy can achieve quick relief of allergic symptoms and long-lasting curative effects.

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References

  • Akdis, M., Akdis, C.A. (2007). Mechanisms of allergen-specific immunotherapy. J Allergy Clin Imunol, 119(4), 780–789.

    Article  CAS  Google Scholar 

  • Bousquet, J., Lockey, R.F., Malling, H.J. (1998). WHO position paper-Allergen immunotherapy, therapeutic vaccines for allergic diseases. Allergy, 53(Suppl 44), 1–42.

    Google Scholar 

  • Chu, J.C.L., Wen, T.H., Chen, X.J. (1981). Treatment of asthmatic patients sensitive to mites (Dermatophagoides farinae). A four-year study of immunotherapy with Dermatophagoides farinae. Ann Allergy, 47, 107–109.

    PubMed  CAS  Google Scholar 

  • Heymann, P.W., Chapman, M.D., Aalberse, R.C., et al. (1989). Antigenic and structural analysis of group II allergens (Der f I and Der p II) from house dust mites (Dermatophagoides spp.). J Allergy Clin Immunol, 83960, 1055–1067.

    Article  Google Scholar 

  • Huang, Y., Chen, K.H., Dong, F., et al. (1997). Studies on mite oral extract depressing the incidence of bronchial asthma after bronchiolitis. Pract Paed Clin J, 12(6), 367–369 (in Chinese).

    Google Scholar 

  • Huang, Y., Li, J.B., Li, F.R., et al. (2003). Clinical observations on child asthma control with mite oral extract. Chongqing Med, 32, 427–429 (in Chinese).

    Google Scholar 

  • Jin, M.L., Cai, Y.Y., Wang, B.L., et al. (1995). Efficacy of slow releasing mite extract in treatment of allergic asthma. Shanghai Med, 18, 151–152 (in Chinese).

    Google Scholar 

  • Pan, X.L., Geng, Y.C., Wang, S.A., et al. (2001). Comparison of the curative efficacies of child asthma between oral and injection dust mite vaccines. Chin J Appl Immun Allergy Asthma, 5(3), 225–227 (in Chinese with English abstract).

    CAS  Google Scholar 

  • Peng, Z., Wen, T., Hong, S.S., et al. (1985). Skin prick test, nasal provocation test and measurement of specific IgE with dust mite extract in allergic asthmatic patients. Shanghai J Immunol, 5, 29–33 (in Chinese with English abstract).

    Google Scholar 

  • Peng, Z., Nacierio, R.M., Norman, P.S., et al. (1992). Quantitative IgE and IgG-subclass responses during and after long-term ragweed immunotherapy. J Allergy Clin Immunol, 89(2), 519–529.

    Article  PubMed  CAS  Google Scholar 

  • Su, S.L., Zhang, Y.P., Wen, T.H. (2001). Long and short immunotherapy effect upon bronchial asthma using the fluid extract of dust mite. Chin J Appl Immun Allergy Asthma, 5(2), 4–50 (in Chinese with English abstract).

    Google Scholar 

  • Voorhorst, R., Spieksma, F.T.M., Varekamp, N. (1969). House Dust Atopy and the House Dust Mite Dermatophagoides pteronyssinus (Trouessart, 1877). Leiden: Stafleu’s Scientific Publishing Co., pp. 159.

    Google Scholar 

  • Wang, B.L., Cai, Y.Y., Cheng, X.L., et al. (1994). Introduction of a new slow releasing Dermatophagoides farinae extract in treatment of allergic asthma. Acta Acad Med Shanghai, 21, 480 (in Chinese).

    Google Scholar 

  • Wen, T., Wang, E., Shen, S., et al. (1990). Allergenic potency of SMU Df extract in comparison with VUS Df extract, and diagnosis and immunotherapy for atopic dermatitis and rhinitis with SMU-Df extract in China. Arb Paul-Ehrlich-Institut, 85, 217–227.

    Google Scholar 

  • Wen, Y.Y., Wen, T.H., Hua, Z.Y., et al. (1992). Evaluation of skin prick test with dust mite sensitive asthma. Chin J Pharmaceut, 23(7), 315–317 (in Chinese with English abstract).

    Google Scholar 

  • Wen, T., Cai, Y.Y., Chen, X.J., et al. (1998). Safety analysis of diagnosis and immunotherapy with Dermatophagoides farinae extract in allergic patients in China. Syst Appl Acarol, 3, 105–112.

    Google Scholar 

  • Wen, T., Wang, B.L., Jin, M.L., et al. (1997). Oral versus subcutaneous immunotherapy with dust mite allergen in asthmatics in China. The 5th WPAS and the 7th Korea-Japan Joint Allergy symposium (Seoul), Abstract, p.115.

    Google Scholar 

  • Wen, T.H. (2005). Dust mite sensitivity and asthma. In: Li, M.H., et al. (ed). Asthmology (2nd ed). Beijing: People’s Medical Publishing House, pp. 936–960.

    Google Scholar 

  • Wen, T.H. (2006). Vaccines for child allergic asthma and immunotherapy per os. Chinese Medical Association-Subassociation of Allergology (ed). All China Symposiums on Diagnosis and Management of Child Allergic Diseases in Advance. Chengdu, pp. 38–40 (in Chinese).

    Google Scholar 

  • Zhang, Z.X., Zhao, Y., Li, H.W., et al. (2003). Clinical observation on the curative efficacy of child asthma controlled by Manyi or, sublingual mite vaccine. Chin J Appl Immun Allergy Asthma, 7(1), 74–75 (in Chinese with English abstract).

    Google Scholar 

  • Zhao, J., Chen, Y.Z., Ding, Y., et al. (1999). Oral mite desensitization solution as supplementary therapy in treating children asthma. Chin Pract Paed J, 14(11), 661–663 (in Chinese with English abstract).

    Google Scholar 

  • Zheng, Y., Yin, R., Liang, C.Y., et al. (2000). Oral mite vaccine in immunotherapy of allergic rhinitis and asthma. West China Med J, 15(3), 294.

    Google Scholar 

  • Zhu, J.R., Wen, T.H., Chen, N.Z. (1992). Curative efficacy of allergic rhinitis by percutaneous application of glycerinated Dermatophagoides farinae extract. Clin ENT J, 6(1), 50 (in Chinese).

    Google Scholar 

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© 2012 Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg

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Wen, TH. (2012). Prospective Studies on Mite (Dermatophagoides farinae) Allergen Immunotherapy in China. In: Multidisciplinary Approaches to Allergies. Advanced Topics in Science and Technology in China. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31609-8_18

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