Abstract
Spinal cord tumors are lesions that occur within or adjacent to the spinal cord. They are considered to be intra-axial in location and can be either primary or metastatic. Spinal cord tumors are relatively rare and account for 2 % of all central nervous system tumors. Tumors arising within the spinal cord itself are called intramedullary tumors, one-third of which are located in the intramedullary compartment. The spinal cord has the characteristic of integrated neuronal axons existing within a small diameter. Since spinal cord pathways are interrupted, neurologic dysfunction may be produced distally. Major complaints of the patients are unremitting pain, sensory dysesthesia, and muscular weakness.
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References
Kim MS et al (2001) Intramedullary spinal cord astrocytoma in adults: postoperative outcome. J Neurooncol 52(1):85–94
Reimer R, Onofrio BM (1985) Astrocytomas of the spinal cord in children and adolescents. J Neurosurg 63(5):669–675
McGuire CS, Sainani KL, Fisher PG (2009) Both location and age predict survival in ependymoma: a SEER study. Pediatr Blood Cancer 52(1):65–69
McGirt MJ et al (2008) Extent of surgical resection of malignant astrocytomas of the spinal cord: outcome analysis of 35 patients. Neurosurgery 63(1):55–60; discussion 60–61
Sgouros S, Malluci CL, Jackowski A (1996) Spinal ependymomas–the value of postoperative radiotherapy for residual disease control. Br J Neurosurg 10(6):559–566
Whitaker SJ et al (1991) Postoperative radiotherapy in the management of spinal cord ependymoma. J Neurosurg 74(5):720–728
Shaw EG et al (1986) Radiotherapeutic management of adult intraspinal ependymomas. Int J Radiat Oncol Biol Phys 12(3):323–327
Marcus RB Jr, Million RR (1990) The incidence of myelitis after irradiation of the cervical spinal cord. Int J Radiat Oncol Biol Phys 19(1):3–8
McCunniff AJ, Liang MJ (1989) Radiation tolerance of the cervical spinal cord. Int J Radiat Oncol Biol Phys 16(3):675–678
Jeremic B, Djuric L, Mijatovic L (1991) Incidence of radiation myelitis of the cervical spinal cord at doses of 5500 cGy or greater. Cancer 68(10):2138–2141
Fowler JF et al (2000) Clinical radiation doses for spinal cord: the 1998 international questionnaire. Radiother Oncol 55(3):295–300
Emami B et al (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21(1):109–122
Nelson JW et al (2008) Stereotactic body radiotherapy for lesions of the spine and paraspinal regions. Int J Radiat Oncol Biol Phys 73(5):1369–1375
Gerszten PC, Welch WC (2004) Cyberknife radiosurgery for metastatic spine tumors. Neurosurg Clin N Am 15(4):491–501
Kumada H et al (2004) Verification of the computational dosimetry system in JAERI (JCDS) for boron neutron capture therapy. Phys Med Biol 49(15):3353–3365
Kumada H et al (2004) Improvement of dose calculation accuracy for BNCT dosimetry by the multi-voxel method in JCDS. Appl Radiat Isot 61(5):1045–1050
Coderre JA et al (1995) Comparative assessment of single-dose and fractionated boron neutron capture therapy. Radiat Res 144(3):310–317
Morris GM et al (2002) Long-term infusions of p-boronophenylalanine for boron neutron capture therapy: evaluation using rat brain tumor and spinal cord models. Radiat Res 158(6):743–752
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© 2012 Springer-Verlag Berlin Heidelberg
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Nakai, K., Matsumura, A. (2012). Feasibility for Intramedullary Spinal Glioma. In: Sauerwein, W., Wittig, A., Moss, R., Nakagawa, Y. (eds) Neutron Capture Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31334-9_23
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DOI: https://doi.org/10.1007/978-3-642-31334-9_23
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