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Atlas of PET/MR Imaging in Oncology pp 29–40Cite as

Technical Principles and Protocols of PET/MR Imaging

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Abstract

PET and MRI are two well-established medical imaging modalities that are used frequently as diagnostic tools in a wide range of clinical indications providing complementary information. MRI can provide anatomical information with very high spatial resolution, and functional measurements at organ and tissue level with high diagnostic sensitivity. On the other hand, PET images functional processes at cellular and sub-cellular level with very high diagnostic specificity and high tracer detection sensitivity (10−11–10−12 mol/l) but with an inferior to MRI spatial resolution. This complementary matching of capabilities renders both PET(/CT) and MRI necessary in several disease pathways, particularly in oncology and neurology. A significant workflow limitation, when both modalities are needed, is the physical and organisational separation of the two systems. Patients needing both PET and MR imaging are referred independently and often imaged after a significant amount of time. This renders the fusion of information from both examinations difficult or even impossible due to disease status changes or several other technical and organisational factors. It is, therefore, expected that where MRI is the preferred imaging modality versus CT, PET-MR should be more clinically useful than PET-CT and a combined single examination could provide significant benefits to both the patient and the hospital.

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Authors and Affiliations

  1. PET/MR, Philips Healthcare, Guildford Business Park, Guildford, Surrey, GU2 8XH, UK

    A. Kalemis

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  1. , Nuclear Medicine Division, University Hospital of Geneva, 24, Rue Micheli-du-Crest, Geneva, 1205, Switzerland

    Osman Ratib

  2. Klinikum rechts der Isar, Nuklearmedizinische Klinik u. Poliklinik, Technische Universität München, Ismaninger Str. 22, Munich, 61675, Germany

    Markus Schwaiger

  3. General Hospital Vienna, Center for Medical Physics, Medical University Vienna, Waehringer Gürtel 18-20, Vienna, 1090, Wien, Austria

    Thomas Beyer

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Kalemis, A. (2013). Technical Principles and Protocols of PET/MR Imaging. In: Ratib, O., Schwaiger, M., Beyer, T. (eds) Atlas of PET/MR Imaging in Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31292-2_3

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