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Aptamer-Functionalized Nanomaterials for Biological and Biomedical Applications

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Handbook of Nanomaterials Properties

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Abstract

Nanomaterials have been extensively studied in a variety of fields ranging from energy conversion to clinical diagnosis. In this chapter, we focus our discussion on aptamer-functionalized nanomaterials. Nucleic acid aptamers are an emerging class of synthetic affinity molecules with numerous merits such as high binding specificity, high binding affinity, small sizes, and stable structures. Therefore, the integration of aptamers and nanomaterials holds great potential for the development of novel nanotechnology platforms for applications of various fields such as molecular detection, cell imaging and isolation, drug delivery, and integrated imaging and therapy.

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Authors and Affiliations

  1. Pennsylvanian State University, University Park, PA, 16802, USA

    Yike Huang & Yong Wang

Authors
  1. Yike Huang
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  2. Yong Wang
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Correspondence to Yike Huang .

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Editors and Affiliations

  1. Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics, Ohio State University, Columbus, Ohio, USA

    Bharat Bhushan

  2. Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, USA

    Dan Luo

  3. Division of Restorative, Prosthetic and Primary Care, The Ohio State University, College of Dentistry, Columbus, Ohio, USA

    Scott R. Schricker

  4. Department of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA

    Wolfgang Sigmund

  5. Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA

    Stefan Zauscher

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Huang, Y., Wang, Y. (2014). Aptamer-Functionalized Nanomaterials for Biological and Biomedical Applications. In: Bhushan, B., Luo, D., Schricker, S., Sigmund, W., Zauscher, S. (eds) Handbook of Nanomaterials Properties. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31107-9_51

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