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Palatal Wound Healing: The Effects of Scarring on Growth

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Cleft Lip and Palate

Abstract

Cleft palate patients often develop growth disturbances of the midfacial region after primary surgery. This is mainly caused by wound contraction and scar formation on the palate. The chapter gives an overview of the wound healing process with emphasis on wound contraction and scar formation. Some specific features of the palatal wound healing process are highlighted. Further, the effects of palatal repair on growth of the maxilla and development of the dentition are reviewed, as well as possible means to improve the clinical outcome. This review is based on clinical evaluations, experimental research in animal models, and on in vitro experiments using cell culturing and tissue engineering techniques.

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Authors and Affiliations

  1. Department of Orthodontics and Craniofacial Biology, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, The Netherlands

    Johannes W. Von den Hoff Ph.D. & Jaap C. Maltha Ph.D.

  2. Department of Orthodontics and Craniofacial Biology, Cleft Palate Craniofacial Unit, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, The Netherlands

    Anne Marie Kuijpers-Jagtman DDS, Ph.D.

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  1. Johannes W. Von den Hoff Ph.D.
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  2. Jaap C. Maltha Ph.D.
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  3. Anne Marie Kuijpers-Jagtman DDS, Ph.D.
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Correspondence to Johannes W. Von den Hoff Ph.D. .

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    Samuel Berkowitz

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Von den Hoff, J.W., Maltha, J.C., Kuijpers-Jagtman, A.M. (2013). Palatal Wound Healing: The Effects of Scarring on Growth. In: Berkowitz, S. (eds) Cleft Lip and Palate. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30770-6_14

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