Advertisement

Outer Membrane Vesicles and the Biofilm Formation

  • S. N. ChatterjeeEmail author
  • Keya Chaudhuri
Chapter
Part of the SpringerBriefs in Microbiology book series (BRIEFSMICROBIOL)

Abstract

Plenty of outer membrane vesicles (OMVs) are often found associated with the parent bacteria forming a biofilm. The functions of these OMVs in the biofilm are discussed in this chapter. Additional genetic and other studies are required to decide the exact role of OMVs and DNA in the formation of biofilm.

Keywords

OMVs Biofilm DNA Genetics LPS 

References

  1. Bomberger JM, Maceachran DP, Coutermarsh BA, Ye S, O’Toole GA, Stanton BA (2009) Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. PLoS Pathog 5:e1000382PubMedCrossRefGoogle Scholar
  2. Chatterjee SN, Chaudhuri K (2006) Lipopolysaccharides of Vibrio cholerae: III. Biological functions. Biochim Biophys Acta 1762:1–16PubMedCrossRefGoogle Scholar
  3. Chaudhuri K, Chatterjee SN (2009) Cholera toxins. Springer, BerlinCrossRefGoogle Scholar
  4. Costerton JW, Lewandowski Z, Caldwell DE, Korber DR, Lappin-Scott HM (1995) Microbial biofilms. Annu Rev Microbiol 49:711–745PubMedCrossRefGoogle Scholar
  5. Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: a common cause of persistent infections. Science 284:1318–1322PubMedCrossRefGoogle Scholar
  6. Ellis TN, Kuehn MJ (2010) Virulence and immunomodulatory roles of bacterial outer membrane vesicles. Microbiol Mol Biol Rev 74:81–94PubMedCrossRefGoogle Scholar
  7. Grenier D, Mayrand D (1987) Functional characterization of extracellular vesicles produced by Bacteroides gingivalis. Infect Immun 55:111–117PubMedGoogle Scholar
  8. Inagaki S, Onishi S, Kuramitsu HK, Sharma A (2006) Porphyromonas gingivalis vesicles enhance attachment, and the leucine-rich repeat BspA protein is required for invasion of epithelial cells by “Tannerella forsythia”. Infect Immun 74:5023–5028PubMedCrossRefGoogle Scholar
  9. Kamaguchi A, Nakayama K, Ichiyama S, Nakamura R, Watanabe T et al (2003a) Effect of Porphyromonas gingivalis vesicles on coaggregation of Staphylococcus aureus to oral microorganisms. Curr Microbiol 47:485–491PubMedCrossRefGoogle Scholar
  10. Kamaguchi A, Ohyama T, Sakai E, Nakamura R, Watanabe T, Baba H, Nakayama K (2003b) Adhesins encoded by the gingipain genes of Porphyromonas gingivalis are responsible for co-aggregation with Prevotella intermedia. Microbiology 149:1257–1264PubMedCrossRefGoogle Scholar
  11. Kierek K, Watnick PI (2003) The Vibrio cholerae O139 O-antigen polysaccharide is essential for Ca2 + -dependent biofilm development in sea water. Proc Natl Acad Sci USA 100:14357–14362PubMedCrossRefGoogle Scholar
  12. Kulp A, Kuehn MJ (2010) Biological functions and biogenesis of secreted bacterial outer membrane vesicles. Annu Rev Microbiol 64:163–184PubMedCrossRefGoogle Scholar
  13. Lawrence JR, Korber DR, Hoyle BD, Costerton JW, Caldwell DE (1991) Optical sectioning of microbial biofilms. J Bacteriol 173:6558–6567PubMedGoogle Scholar
  14. MacDonald KL, Beveridge TJ (2002) Bactericidal effect of gentamicin-induced membrane vesicles derived from Pseudomonas aeruginosa PAO1 on gram-positive bacteria. Can J Microbiol 48:810–820PubMedCrossRefGoogle Scholar
  15. Mashburn-Warren L (2008) Quinolone trafficking via outer membrane vesicles in Pseudomonas aeruginosa. Dissertation for the Doctor of Philosophy Thesis, University of Texas, AustinGoogle Scholar
  16. Mayrand D, Grenier D (1989) Biological activities of outer membrane vesicles. Can J Microbiol 35:607–613PubMedCrossRefGoogle Scholar
  17. Mizunoe Y, Wai SN, Takade A, Yoshida SI (1999) Isolation and characterization of rugose form of Vibrio cholerae O139 strain MO10. Infect Immun 67:958–963PubMedGoogle Scholar
  18. Nesper J, Lauriano CM, Klose KE, Kapfhammer D, Kraiss A, Reidl J (2001) Characterization of Vibrio cholerae O1 El tor galU and galE mutants: influence on lipopolysaccharide structure, colonization, and biofilm formation. Infect Immun 69:435–445PubMedCrossRefGoogle Scholar
  19. Olczak T, Wojtowicz H, Ciuraszkiewicz J, Olczak M (2010) Species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of Porphyromonas gingivalis HmuY. BMC Microbiol 10:134PubMedCrossRefGoogle Scholar
  20. Patrick S, McKenna JP, O’Hagan S, Dermott E (1996) A comparison of the haemagglutinating and enzymic activities of Bacteroides fragilis whole cells and outer membrane vesicles. Microb Pathog 20:191–202PubMedCrossRefGoogle Scholar
  21. Ramsey MM, Whiteley M (2004) Pseudomonas aeruginosa attachment and biofilm development in dynamic environments. Mol Microbiol 53:1075–1087PubMedCrossRefGoogle Scholar
  22. Renelli M, Matias V, Lo RY, Beveridge TJ (2004) DNA-containing membrane vesicles of Pseudomonas aeruginosa PAO1 and their genetic transformation potential. Microbiology 150:2161–2169PubMedCrossRefGoogle Scholar
  23. Rocchetta HL, Burrows LL, Lam JS (1999) Genetics of O-antigen biosynthesis in Pseudomonas aeruginosa. Microbiol Mol Biol Rev 63:523–553PubMedGoogle Scholar
  24. Schooling SR, Beveridge TJ (2006) Membrane vesicles: an overlooked component of the matrices of biofilms. J Bacteriol 188:5945–5957PubMedCrossRefGoogle Scholar
  25. Schooling SR, Hubley A, Beveridge TJ (2009) Interactions of DNA with biofilm-derived membrane vesicles. J Bacteriol 191:4097–4102PubMedCrossRefGoogle Scholar
  26. Unal CM, Schaar V, Riesbeck K (2010) Bacterial outer membrane vesicles in disease and preventive medicine. Semin Immunopathol 33:395–408PubMedCrossRefGoogle Scholar
  27. Wai SN, Mizunoe Y, Takade A, Kawabata SI, Yoshida SI (1998) Vibrio cholerae O1 strain TSI-4 produces the exopolysaccharide materials that determine colony morphology, stress resistance, and biofilm formation. Appl Environ Microbiol 64:3648–3655PubMedGoogle Scholar
  28. Watnick PI, Kolter R (1999) Steps in the development of a Vibrio cholerae El Tor biofilm. Mol Microbiol 34:586–595PubMedCrossRefGoogle Scholar
  29. Watnick PI, Fullner KJ, Kolter R (1999) A role for the mannose-sensitive hemagglutinin in biofilm formation by Vibrio cholerae El Tor. J Bacteriol 181:3606–3609PubMedGoogle Scholar
  30. Whitchurch CB, Tolker-Nielsen T, Ragas PC, Mattick JS (2002) Extracellular DNA required for bacterial biofilm formation. Science 295:1487PubMedCrossRefGoogle Scholar
  31. Yildiz FH, Schoolnik GK (1999) Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation. Proc Natl Acad Sci USA 96:4028–4033PubMedCrossRefGoogle Scholar
  32. Yildiz FH, Dolganov NA, Schoolnik GK (2001) VpsR, a Member of the Response Regulators of the Two-Component Regulatory Systems, Is Required for Expression of vps Biosynthesis Genes and EPS(ETr)-Associated Phenotypes in Vibrio cholerae O1 El Tor. J Bacteriol 183:1716–1726PubMedCrossRefGoogle Scholar

Copyright information

© The Author(s) 2012

Authors and Affiliations

  1. 1.BiophysicsFormerly of Saha Institute of Nuclear PhysicsKolkataIndia

Personalised recommendations