Gram-Negative Bacteria: The cell Membranes
This chapter presents a brief outline of our current knowledge of the structures of the bounding membranes (the inner and the outer membranes and the intermediate periplasmic layer) of a Gram-negative bacterial cell. Also the structure and chemical composition of the outer membrane vesicles (OMVs) originating from the surface of these bacteria including their proteomic profile, as obtained mainly by mass spectroscopic and related studies, have been presented in brief.
KeywordsInner membrane Outer membrane Peptidoglycan OMVs Structure Chemical composition Mass spectrometry Protein profile
- Chatterjee SN, Das J (1966) Secretory activity of Vibrio cholerae as evidenced by electron microscopy. In: Uyeda (ed) Electron microscopy, Maruzen Co. Ltd, TokyoGoogle Scholar
- Kahnt J, Aguiluz K, Koch J, Treuner-Lange A, Konovalova A et al (2010) Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. J Proteome Res 9:5197–5208PubMedCrossRefGoogle Scholar
- McBroom AJ, Kuehn MJ (2005) Outer membrane vesicles In: III RC (ed) EcoSal—Escherichia coli and Salmonella : cellular and molecular biology. American Society for Microbiology Press, WashingtonGoogle Scholar
- Zhu W, Thomas CE, Chen CJ, Van Dam CN, Johnston RE, Davis NL, Sparling PF (2005) Comparison of immune responses to gonococcal PorB delivered as outer membrane vesicles, recombinant protein, or Venezuelan equine encephalitis virus replicon particles. Infect Immun 73:7558–7568PubMedCrossRefGoogle Scholar