Discovery of the Outer Membrane Vesicles: Revisiting Contemporary Works

  • S. N. ChatterjeeEmail author
  • Keya Chaudhuri
Part of the SpringerBriefs in Microbiology book series (BRIEFSMICROBIOL)


The discovery and mechanism of formation and release of outer membrane vesicles (OMVs) by the actively growing Vibrio cholerae cells and their interpretation as a novel secretion mechanism are revisited. Also a brief account of contemporary works, an initial criticism describing that the OMVs were of artifactual origin and the subsequent re-establishment of the fact that the OMVs are not a product of cell lysis and are formed during the active growth of Gram-negative bacteria, have also been revisited for the historical record.


OMVs Discovery Mode of formation  Criticism Confirmation Contemporary works 


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Copyright information

© The Author(s) 2012

Authors and Affiliations

  1. 1.BiophysicsFormerly of Saha Institute of Nuclear PhysicsKolkataIndia
  2. 2.Molecular and Human Genetics DivisionIndian Institute of Chemical BiologyKolkataIndia

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