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Mouse-Induced Pluripotent Stem Cells

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Mouse Development

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 55))

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Abstract

Pluripotent stem cells belong to a unique population of cells, which can self-renew indefinitely and have the potential to give rise to all cell types in an organism. Generally, pluripotent stem cells include embryonic stem cells (ESCs), embryonic germ cells (EGCs), and embryonal carcinoma cells (ECCs) (Boiani and Scholer 2005). In 2006, a new type of pluripotent stem cells, induced pluripotent stem cells (iPSCs), was established by direct reprogramming of differentiated somatic cells (Takahashi and Yamanaka 2006). The unique properties of iPSCs make them extremely attractive in regenerative medicine, drug screening, disease modeling, as well as study of developmental biology (Cyranoski 2008; Maherali and Hochedlinger 2008; Nishikawa et al. 2008).

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Authors and Affiliations

  1. Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine/Shanghai Institutes of Biological Sciences, CAS, Shanghai, 200025, China

    Hui Zhang & Ying Jin

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  1. Hui Zhang
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  2. Ying Jin
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Correspondence to Ying Jin .

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Editors and Affiliations

  1. CNRS UMR 6061, Fac. Médecine, Université de Rennes 1, Rennes CX, 35043, France

    Jacek Z. Kubiak

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Zhang, H., Jin, Y. (2012). Mouse-Induced Pluripotent Stem Cells. In: Kubiak, J. (eds) Mouse Development. Results and Problems in Cell Differentiation, vol 55. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30406-4_20

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