Abstract
We are developing LINDSAY Virtual Human, a 3-dimensional, interactive computer model of male and female anatomy and physiology. LINDSAY is designed to be used for medical education. One key characteristic of LINDSAY is the integration of computational models across a range of spatial and temporal scales. We simulate physiological processes in an integrative fashion: from the body level to the level of organs, tissues, cells, and sub-cellular structures. For use in the classroom, we have built LINDSAY Presenter, a 3D slide-based visualization and exploration environment that presents different scenarios within the simulated human body. We are developing LINDSAY Composer to create complex scenes for demonstration, exploration and investigation of physiological scenarios. At LINDSAY Composer′s core is a graphical programming environment, which facilitates the composition of complex, interactive educational modules around the human body.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Entity systems are the future of MMOG development (September 2007), http://t-machine.org/index.php/2007/09/03/entity-systems-are-the-future-of-mmog-development-part-1
Evolve your hierarchy (January 2007), http://cowboyprogramming.com/2007/01/05/evolve-your-heirachy
Harvard BioVisions (January 2012), http://multimedia.mcb.harvard.edu
Ackerman, M.J., Yoo, T., Jenkins, D.: From data to knowledge - the visible human project® continues. In: MEDINFO 2001, pp. 887–890 (2001)
Årzén, K., Bicchi, A., Dini, G., Hailes, S., Johanesson, K., Lygeros, J., Tzes, A.: A component-based approach to the design of networked control systems. European Journal of Control 13(2), 261–279 (2007)
Bauer, M., Bruegge, B., Klinker, G., MacWilliams, A., Reicher, T., Riß, S., Sandor, C., Wagner, M.: Design of a component-based augmented reality framework. In: International Symposium on Augmented Reality, Los Alamitos, CA, USA, p. 45 (2001)
Bonabeau, E., Dorigo, M., Theraulaz, G.: Swarm Intelligence: From Natural to Artificial Systems. Santa Fe Institute Studies in the Sciences of Complexity. Oxford University Press, New York (1999)
Burleigh, I., Suen, G., Jacob, C.: Dna in action! a 3d swarm-based model of a gene regulatory system. In: First Australian Conference on Artificial Life, ACAL 2003, Canberra, Australia (2003)
Camazine, S., Deneubourg, J.-L., Franks, N.R., Sneyd, J., Theraulaz, G., Bonabeau, E.: Self-Organization in Biological Systems. Princeton Studies in Complexity. Princeton University Press, Princeton (2003)
COLLADA.org. Collada - digital asset and fx exchange schema (April 2010), http://www.collada.org
de Lara, E., Wallach, D.S., Zwaenepoel, W.: Puppeteer: Component-based adaptation for mobile computing. In: USENIX Symposium on Internet Technologies and Systems (2000)
Heineman, G.T., Councill, W.T.: Component-Based Software Engineering. ACM Press (2001)
Hoar, R., Penner, J., Jacob, C.: Transcription and evolution of a virtual bacteria culture. In: IEEE Congress on Evolutionary Computation. IEEE Press, Canberra (2003)
Hunter, P.J., Borg, T.K.: Integration from proteins to organs: the physiome project. Nature Reviews: Molecular Cell Biology 4, 237–243 (2003)
Jacob, C., Barbasiewicz, A., Tsui, G.: Swarms and genes: Exploring λ-switch gene regulation through swarm intelligence. In: IEEE Congress on Evolutionary Computation, CEC 2006 (2006)
Jacob, C., Burleigh, I.: Biomolecular swarms: An agent-based model of the lactose operon. Natural Computing 3(4), 361–376 (2004)
Johnson, S.: Emergence: The Connected Lives of Ants, Brains, Cities, and Software. Scribner, New York (2001)
Leavens, G.T., Sitaraman, M. (eds.): Foundations of component-based systems. Cambridge University Press, New York (2000)
Lewandowski, S.M.: Frameworks for component-based client server computing. ACM Comput. Surv. 30(1), 3–27 (1998)
Mikic-Rakic, M., Malek, S., Medvidovic, N.: Improving availability in large, distributed component-based systems via redeployment. Component Deployment, 83–98 (2005)
Mitsuhashi, N., Fujieda, K., Tamura, T., Kawamoto, S., Takagi, T., Okubo, K.: BodyParts 3D: 3D structure database for anatomical concepts. Nucl. Acids Res. (2008), gkn613
N. L. of Medicine. National library of medicine: The visible human project (April 2010), http://www.nlm.nih.gov/research/visible/visible_human.html
Penner, J., Hoar, R., Jacob, C.: Bacterial chemotaxis in silico. In: First Australian Conference on Artificial Life, ACAL 2003, Canberra, Australia (2003)
Pogson, M., Smallwood, R., Qwarnstrom, E., Holcomb, M.: Formal agent-based modelling of intracellular chemical interactions. BioSystems (2006)
Roussain, H., Guidec, F.: Cooperative component-based software deployment in wireless ad hoc networks. Component Deployment, 1–16 (2005)
Seifert, M.F.: Visible human projects special issue. Clinical Anatomy 19(3), 191–289 (2010)
Sensen, C.W., Soh, J.: CAVEman, An Object-Oriented Model of the Human Body. In: Sensen, C.W., Soh, J. (eds.) Advanced Imaging in Biology and Medicine, vol. II, pp. 289–300. Springer, Heidelberg (2009)
Stoy, C.: Game Object Component System. In: Game Programming Gems 6, pp. 393–403. Charles River Media (2006)
Tietze, D. A.: A Framework for Developing Component-based Co-operative Applications. PhD thesis, Technische Universität Darmstadt, Darmstadt, Germany (2000)
von Mammen, S., Davison, T., Baghi, H., Jacob, C.: Component-based networking for simulations in medical education. In: MediaWiN 2010: IEEE Workshop on Multimedia Applications Over Wireless Networks, Riccione, Italy. IEEE Computer Society, IEEE Press, Washington (2010)
Walker, D.C., Southgate, J.: The virtual cell–a candidate co-ordinator for ’middle-out’ modelling of biological systems. Briefings in Bioinformatics 10(4), 450–461 (2009)
Wilson, K.: Game object structure: Inheritance vs aggregation (July 2002)
Wolfram, S.: A new kind of science. Wolfram Media Inc., Champaign (2002)
Yazdanbod, I., Marcus, S.: An agent-based simulation of blood coagulation processes. The Journal of Undergraduate Research in Alberta 1(1), 13–18 (2010)
Zygote Inc. Zygote human anatomy 3d model (April 2010), http://www.zygote.com
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Jacob, C. et al. (2012). LINDSAY Virtual Human: Multi-scale, Agent-based, and Interactive. In: Kołodziej, J., Khan, S., Burczy´nski, T. (eds) Advances in Intelligent Modelling and Simulation. Studies in Computational Intelligence, vol 422. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30154-4_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-30154-4_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-30153-7
Online ISBN: 978-3-642-30154-4
eBook Packages: EngineeringEngineering (R0)