Zusammenfassung
Die physiologische Ernährung von Reifgeborenen wurde in ▶ Kap. 13 beschrieben. Auch und gerade für Frühgeborene ist Muttermilch wegen ihrer supranutritiven Effekte (z. B. Infektionsprophylaxe) die bevorzugte Nahrung. Wegen des u. a. höheren Nährstoffbedarfs von Frühgeborenen sollte die Mutter- bzw. Frauenmilch mit Nährstoffen angereichert werden. Steht keine Frauenmilch zur Verfügung, sollte z.B. bei sehr unreifen Frühgeborenen Frühgeborenenspezialformula mit einer höheren Energiedichte verwendet werden. Für die Aminosäure- und Kohlenhydratanreicherung der Frauenmilch stehen spezielle industriell gefertigte Supplemente zur Verfügung (▶ Kap. 19). Hydrolisatnahrungen können im Vergleich zu Nahrungen mit unmodifiziertem Kuhmilchprotein eine mögliche Sensibilisierung reduzieren oder verhindern. Zusätzlich hat sich die enterale Supplementation mit Multivitaminpräparaten, Eisen, Kalzium/Phosphat bei Frühgeborenen unabhängig von Frauenmilch- oder Formulaernährung bewährt.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Abschn. 20.1 bis Abschn. 20.7 und Abschn. 20.9
American Academy of Pediatrics Committee on Nutrition (1985) Nutritional needs of low-birth-weight infants. Pediatrics 75: 976–986
Baker H, Frank O, Thomson AD, Langer A, Munves ED, Angelis B de, Kaminetzky HA (1975) Vitamin profile of 174 mothers and newborns at parturition. Am J Clin Nutr 28: 59–65
Baydas G, Karatas F, Gursu MF, Bozkurt HA, Ilhan N, Yasar A, Canatan H (2002) Antioxidant vitamin levels in term and preterm infants and their relation to maternal vitamin status. Arch Med Res 33: 276–280
Bernardi JL, Goulart AL, Amancio OM (2003) Growth and energy and protein intake of preterm newborns in the first year of gestation-corrected age. Sao Paulo Med J 121: 5–8
Bronner F, Salle BL, Putet G, Rigo J, Senterre J (1992) Net calcium absorption in premature infants: results of 103 metabolic balance studies. Am J Clin Nutr 56: 1037–1044
Burt BA (1999) The case for eliminating the use of dietary fluoride supplements for young children. J Public Health Dent 59: 269–274
Butte NF, Garza C, Johnson CA, Smith EO, Nichols BL (1984) Longitudinal changes in milk composition of mothers delivering preterm and term infants. Early Hum Dev 9: 153–162
Carnielli VP, Luijendijk IH, Goudoever JB van, Sulkers EJ, Boerlage AA, Degenhart HJ, Sauer PJ (1996) Structural position and amount of palmitic acid in infant formulas: effects on fat, fatty acid, and mineral balance. J Pediatr Gastroenterol Nutr 23: 553–560
Casadevall N (2003) Pure red cell aplasia and anti-erythropoietin antibodies in patients treated with epoetin. Nephrol Dial Transplant 18 [Suppl 8] 37–41
Congdon PJ, Horsman A, Ryan SW, Truscott JG, Durward H (1990) Spontaneous resolution of bone mineral depletion in preterm infants. Arch Dis Child 65: 1038–1042
Daaboul J, Sanderson S, Kristensen K, Kitson H (1997) Vitamin D deficiency in pregnant and breast-feeding women and their infants. J Perinatol 17: 10–14
Ehrenkranz RA, Ackerman BA, Nelli CM, Janghorbani M (1985) Absorption of calcium in premature infants as measured with a stable isotope 46Ca extrinsic tag. Pediatr Res 19: 178–184
Ernährungskommission der Österreichischen Gesellschaft für Kinder- und Jugendmedizin (ÖGKJ) (2012) Ernährung Frühgeborener nach der Entlassung. Monatsschr Kinderheikunde 160: 491–498
Food and Drug Administration (1985) Rules and regulations. Nutrient requirements for infant formulas. Fed Reg 50: 45106–45108
Fusch C, Bauer K, Böhles HJ et al.; Working group for developing the guidelines for parenteral nutrition of The German Society for Nutritional Medicine (2009) Neonatology/Paediatrics – Guidelines on Parenteral Nutrition, Chapter 13. Ger Med Sci 18: Doc15
Fusch C, Jochum F (2004) Water, sodium, potassium, and chloride. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant. Wiliams & Wilkins, Baltimore (in press)
Greene HL, Smith LJ (1993) Watersoluble vitamins. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant. Williams & Wilkins, Baltimore
Greer FR (1989) Calcium, phosphorus, and magnesium: how much is too much for infant formulas? J Nutr 119: 1846–1851
Greer FR (1995) Vitamin K deficiency and hemorrhage in infancy. Clin Perinatol 22: 759–777
Greer FR (2000) Vitamin metabolism and requirements in the micropremie. Clin Perinatol 27: 95–118
Greer FR, McCormick A (1988) Improved bone mineralization and growth in premature infants fed fortified own mother‘s milk. J Pediatr 112: 961–969
Gross SJ (1993) Vitamin E. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant. Williams & Wilkins, Baltimore
Hanawa Y (1992) Vitamin K deficiency in infancy: the Japanese experience. Acta Paediatr Jpn 34: 107–116
Hufnagle KG, Khan SN, Penn D, Cacciarelli A, Williams P (1982) Renal calcifications: a complication of long-term furosemide therapy in preterm infants. Pediatrics 70: 360–363
Jochum F, Fuchs A, Cser A, Menzel H, Lombeck I (1995) Trace mineral status of full-term infants fed human milk, milk-based formula or partially hydrolysed whey protein formula. Analyst 120: 905–909
Karlen J, Aperia A, Zetterstrom R (1985) Renal excretion of calcium and phosphate in preterm and term infants. J Pediatr 106: 814–819
Kersting M, Alexy U (2000) Empfehlungen für die Ernährung von Säuglingen. Moeker Merkur, Köln
Koletzko B, Goulet O, Hunt J et al. for the Parenteral Nutrition Guidelines Working Group; European Society for Clinical Nutrition and Metabolism; European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN); European Society of Paediatric Research (ESPR) (2005) 1. Guidelines on Paediatric Parenteral Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), Supported by the European Society of Paediatric Research (ESPR). J Pediatr Gastroenterol Nutr 41 (Suppl 2) S1–87
Koo W (1993) calcium, magnesium, phosphorus and vitamin D. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant. Williams & Wilkins, Baltimore, pp 135–155
Koo WW, Tsang RC, Succop P, Krug-Wispe SK, Babcock D, Oestreich AE (1989) Minimal vitamin D and high calcium and phosphorus needs of preterm infants receiving parenteral nutrition. J Pediatr Gastroenterol Nutr 8: 225–233
Koo WW, Krug-Wispe S, Succop P, Tsang RC, Neylan M (1995) Effect of different vitamin A intakes on very-low-birth-weight infants. Am J Clin Nutr 62: 1216–1220
Kreiter SR, Schwartz RP, Kirkman HN Jr, Charlton PA, Calikoglu AS, Davenport ML (2000) Nutritional rickets in African American breast-fed infants. J Pediatr 137: 153–157
Kumar D, Greer FR, Super DM, Suttie JW, Moore JJ (2001) Vitamin K status of premature infants: implications for current recommendations. Pediatrics 108: 1117–1122
Lemons JA, Moye L, Hall D, Simmons M (1982) Differences in the composition of preterm and term human milk during early lactation. Pediatr Res 16: 113–117
Liu YM, Neal P, Ernst J, Weaver C, Rickard K, Smith DL, Lemons J (1989) Absorption of calcium and magnesium from fortified human milk by very low birth weight infants. Pediatr Res 25: 496–502
Lombeck I, Fuchs A (1994) Zinc and copper in infants fed breast-milk or different formula. Eur J Pediatr 153: 770–776
Macdougall IC (2004) Pure red cell aplasia with anti-erythropoietin antibodies occurs more commonly with one formulation of epoetin alfa than another. Curr Med Res Opin 20: 83–86
Maier RF, Obladen M, Muller-Hansen I et al. (2002) Early treatment with erythropoietin beta ameliorates anemia and reduces transfusion requirements in infants with birth weights below 1,000 g. J Pediatr 141: 8–15
Matos V, Melle G van, Boulat O, Markert M, Bachmann C, Guignard JP (1997) Urinary phosphate/creatinine, calcium/creatinine, and magnesium/creatinine ratios in a healthy pediatric population. J Pediatr 131: 252–257
Moyer-Mileur L, Chan GM, Gill G (1992) Evaluation of liquid or powdered fortification of human milk on growth and bone mineralization status of preterm infants. J Pediatr Gastroenterol Nutr 15: 370–374
Newbrun E (1999) The case for reducing the current Council on Dental Therapeutics fluoride supplementation schedule. J Public Health Dent 59: 263–268
Obladen M, Loui A, Kampmann W, Renz H (1998) Zinc deficiency in rapidly growing preterm infants. Acta Paediatr 87: 685–691
Orzalesi M (1987) Vitamins and the premature. Biol Neonate 52 [Suppl 1]: S97–112
Pabon ML, Lonnerdal B (2000) Bioavailability of zinc and its binding to casein in milks and formulas. J Trace Elem Med Biol 14: 146–153
Perrotta S, Nobili B, Rossi F et al. (2002) Infant hypervitaminosis A causes severe anemia and thrombocytopenia: evidence of a retinol-dependent bone marrow cell growth inhibition. Blood 99: 2017–2022
Pohlandt F (1994a) Bone mineral deficiency as the main factor of dolichocephalic head flattening in very-low-birth-weight infants. Pediatr Res 35: 701–703
Pohlandt F (1994b) Hypothesis: myopia of prematurity is caused by postnatal bone mineral deficiency. Eur J Pediatr 153: 234–236
Pohlandt F (1994c) Prevention of postnatal bone demineralization in very low-birth-weight infants by individually monitored supplementation with calcium and phosphorus. Pediatr Res 35: 125–129
Premji S, Chessell L (2003) Continuous nasogastric milk feeding versus intermittent bolus milk feeding for premature infants less than 1500 grams.
Rodriguez-Rodriguez EM, Sanz-Alaejos M, Diaz-Romero C (2000) Concentrations of iron, copper and zinc in human milk and powdered infant formula. Int J Food Sci Nutr 51: 373–380
Saarela T, Vaarala A, Lanning P, Koivisto M (1999) Incidence, ultrasonic patterns and resolution of nephrocalcinosis in very low birth weight infants. Acta Paediatr 88: 655–660
Sargent JD, Stukel TA, Kresel J, Klein RZ (1993) Normal values for random urinary calcium to creatinine ratios in infancy. J Pediatr 123: 393–397
Sutor AH, Gobel U, Kries RV, Kunzer W, Landbeck G (1990) Vitamin K prophylaxis in the newborn. Blut 60: 275–277
Tinggi U (2003) Essentiality and toxicity of selenium and its status in Australia: a review. Toxicol Lett 137: 103–110
Trotter A, Pohlandt F (2002) Calcium and phosphorus retention in extremely preterm infants supplemented individually. Acta Paediatr 91: 680–683
Tsang RC (1985) Determining the vitamin and mineral requirements of preterm infants. In: Tsang RC (ed) Vitamin and mineral requirements of preterm infants. Dekker, New York, pp 1–8
Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) (1993) Nutritional needs of the preterm infant. Williams & Wilkins, Baltimore
Wabistsch M, et al. (2011) Vitamin-D-Versorgung im Säuglings-, Kindes- und Jugendalter Monatsschrift Kinderheilkunde Volume 159(8) 766-774
Walli R, Stettler T, Largo RH, Fanconi A, Prader A (1980) Gewicht, Länge und Kopfumfang neugeborener Kinder und ihre Abhängigkeit von mütterlichen und kindlichen Faktoren. Normwerte für das intrauterine Wachstum. Helv Paediatr Acta 35: 397–418
Wauben I, Gibson R, Atkinson S (1999) Premature infants fed mothers’ milk to 6 months corrected age demonstrate adequate growth and zinc status in the first year. Early Hum Dev 54: 181–194
Wu SC, Chou YH (2001) Measurement of serum vitamin E isomers in fullterm and preterm infants. Chang Gung Med J 24: 793–798
Ziegler EE, O‘Donnell AM, Nelson SE, Fomon SJ (1976) Body composition of the reference fetus. Growth 40: 329–341
Abschn. 20.8
Alfaleh K, Anabrees J, Bassler D, Al-Kharfi T (2011) Probiotics for prevention of necrotising enterocolitis in preterm infants (review) Cochr Datab Sys Rev: CD005496
AWMF (2010) S2k-Leitlinie der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin (GPNI) Nekrotisierende Enterokolitis. Registernummer 024–009. www.awmf.org (letzter Zugriff: 30.05.2012)
Deshpande G, Shripada R, Patole S, Bulsara M (2010) UpdateD meta-analysis of probiotics for preventing necrotising enterocolitis in preterm neonates. Pediatrics 125: 921–930
Fusch C, Bauer K, Böhles HJ et al. for the Working group for developing the guidelines for parenteral nutrition of The German Society for Nutritional Medicine (2009) Neonatology/Paediatrics - Guidelines on Parenteral Nutrition, Chapter 13. Ger Med Sci 18: Doc 15
Garland SM, Tobin JM, Pirotta M et al. (2011) The ProPrem trial: investigating the effect of probiotics on late onset sepsis in very preterm infants. BMC Infect Dis 11: 210
Mihatsch WA, Braegger CP, Decsi T et al. (2012) Critical systematic review of the level of evidence for routine use of probiotics for reduction of mortality and prevention of necrotising enterocolitis and sepsis in preterm infants. Clin Nutr 31: 6–15
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Jochum, F., Nomayo, A. (2013). Frühgeborene. In: Jochum, F. (eds) Ernährungsmedizin Pädiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29817-2_20
Download citation
DOI: https://doi.org/10.1007/978-3-642-29817-2_20
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-29816-5
Online ISBN: 978-3-642-29817-2
eBook Packages: Medicine (German Language)