Abstract
Severe open tibial fractures are frequently complicated by infection. There is some data that external fixation of these fractures results in fewer and less serious infections than internal fixation. However, there is insufficient data in this regard to justify such a recommendation at this juncture. Therefore, there is a pressing need for a multi-center, prospective, randomized clinical trial to ascertain if there are statistically significant benefits of one fixation type versus the other for tibial fracture. Towards that end we have developed the FixIt Trial which aims to enroll 300 patients with type IIIB or “severe” type IIIA tibial fractures from 23 major civilian and military trauma centers for randomization of treatment and clinical follow-up for one year.
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O’Toole, R.V. (2012). Infections Associated with Severe Open Tibial Fractures. In: Ehrlich, G., DeMeo, P., Costerton, J., Winkler, H. (eds) Culture Negative Orthopedic Biofilm Infections. Springer Series on Biofilms, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29554-6_7
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DOI: https://doi.org/10.1007/978-3-642-29554-6_7
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