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Medikamentöse Langzeittherapie von Epilepsien

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Dooses Epilepsien im Kindes- und Jugendalter

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Zusammenfassung

Die Mitteilung der Diagnose Epilepsie und der Notwendigkeit einer langjährigen medikamentösen Therapie bedeutet für den Betroffenen und seine Familie ein einschneidendes Ereignis. Man muss sich vor Augen halten, dass die Eltern und die schon etwas älteren Patienten mit einem Begriff konfrontiert werden, mit dem sie keine genauen Vorstellungen verbinden; und wenn, dann überwiegend falsche, d. h. Schrecken und Angst erregende.

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Literatur

  • Aldenkamp, AP, Arends J (2004) Effects of epileptiform EEG discharges on cognitive function: is the concept of »transient cognitive impairment« still valid? Epilepsy Behav 5 (Suppl 1): S25–S34

    Article  PubMed  Google Scholar 

  • Beume LA, Steinhoff BJ (2010) Long-term outcome of difficultto-treat epilepsy in childhood. Neuropediatrics 41: 135–139

    Article  PubMed  CAS  Google Scholar 

  • Brodie MJ, Yuen AW (1997) Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group. Epilepsy Res 26: 423–432

    Article  PubMed  CAS  Google Scholar 

  • Camfield P, Camfield C (2008) When is it safe to discontinue AED treatment? Epilepsia 49 (Suppl 9): 25–28

    Article  PubMed  Google Scholar 

  • Chadwick D, Taylor J, Johnson T (1996) Outcomes after seizure recurrence in people with well-controlled epilepsy and the factors that influence it. The MRC Antiepileptic Drug Withdrawal Group. Epilepsia 37: 1043–1050

    Article  PubMed  CAS  Google Scholar 

  • Chaves J, Sander JW (2005) Seizure aggravation in idiopathic generalized epilepsies. Epilepsia 46 (Suppl 9):133–139

    Article  PubMed  Google Scholar 

  • Gayatri NA, Livingston JH (2006) Aggravation of epilepsy by anti-epileptic drugs. Dev Med Child Neurol 48: 394–398

    Article  PubMed  CAS  Google Scholar 

  • Genton P (2000) When antiepileptic drugs aggravate epilepsy. Brain Dev 22: 75–80

    Article  PubMed  CAS  Google Scholar 

  • Hahn A, Fischenbeck A, Stephani U (2004) Induction of epileptic negative myoclonus by oxcarbazepine in symptomatic epilepsy. Epileptic Disord 6: 271–274

    PubMed  Google Scholar 

  • König SA, Elger CE, Vassella F et al. (1998) Recommendations for blood studies and clinical monitoring in early detection of valproate-associated liver failure. Results of a consensus conferences 09.05.–11.05.1997 in Berlin. Nervenarzt 69: 835–840

    Article  PubMed  Google Scholar 

  • Lerman-Sagie T, Watemberg N, Kramer U, Shahar E, Lerman P (2001) Absence seizures aggravated by valproic acid. Epilepsia 42: 941–943

    Article  PubMed  CAS  Google Scholar 

  • Lortie A, Chiron C, Mumford J, Dulac O (1993) The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin. Neurology 43 (Suppl 5): S24–27

    PubMed  CAS  Google Scholar 

  • McTague A, Appleton R (2011) Treatment of difficult epilepsy. Arch Dis Child 96: 200–204

    Article  PubMed  CAS  Google Scholar 

  • Prats JM, Garaizar C, García-Nieto ML, Madoz P (1998) Antiepileptic drugs and atypical evolution of idiopathic partial epilepsy. Pediatr Neurol 18: 402–406

    Article  PubMed  CAS  Google Scholar 

  • Ryvlin, P. (2006) When to start antiepileptic drug treatment: seize twice might not harm. Curr Opin Neurol 19: 154–156

    Article  PubMed  Google Scholar 

  • Sazgar M, Bourgeois BF (2005) Aggravation of epilepsy by antiepileptic drugs. Pediatr Neurol 33: 227–234

    Article  PubMed  Google Scholar 

  • Sirven JI, Sperling M, Wingerchuk DM (2001) Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. Cochrane Database Syst Rev 3: CD001902

    PubMed  Google Scholar 

  • Stafstrom CE (2010) Mechanisms of action of antiepileptic drugs: the search for synergy. Curr Opin Neurol 23: 157–163

    Article  PubMed  CAS  Google Scholar 

  • Stephen LJ, Brodie MJ (2002) Seizure freedom with more than one antiepileptic drug. Seizure 11: 349–351

    Article  PubMed  Google Scholar 

  • Wirrell EC et al. (1997) Long-term psychosocial outcome in typical absence epilepsy. Sometimes a wolf in sheeps’ clothing. Arch Pediatr Adolesc Med 151: 152–158

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Universitätsklinikum Gießen und Marburg, Gießen und Marburg

    Prof. Dr. Bernd A. Neubauer & PD Dr. Andreas Hahn

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  1. Prof. Dr. Bernd A. Neubauer
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  2. PD Dr. Andreas Hahn
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© 2012 Springer-Verlag Berlin Heidelberg

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Neubauer, B.A., Hahn, A. (2012). Medikamentöse Langzeittherapie von Epilepsien. In: Dooses Epilepsien im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29438-9_19

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  • DOI: https://doi.org/10.1007/978-3-642-29438-9_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-29437-2

  • Online ISBN: 978-3-642-29438-9

  • eBook Packages: Medicine (German Language)

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