Skip to main content

Komplikationsmanagement

  • Chapter
  • 3013 Accesses

Zusammenfassung

Ein rechtsventrikuläres Versagen kann bereits präoperativ bestehen oder erst perioperativ entstehen. Es kann auch spät nach Implantation eines LVAD zum Tragen kommen. In diesem Kapitel werden wir uns mit der Vorhersage dieses Phänomens beschäftigen und die perioperativen Maßnahmen zur Prävention und Therapie besprechen. Weiterhin werden Diagnose und Therapiemöglichkeiten des späten rechtsventrikulären Versagens besprochen.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

Literatur zu 9.1

  • Adamson RM, Dembitsky WP, Baradarian S, Chammas J, May-Newman K et al (2011) Aortic valve closure associated with HeartMate left ventricular device support: technical considerations and long-term results. J Heart Lung Transplant 30(5): 576-582

    Article  PubMed  Google Scholar 

  • Argenziano M, Choudhri AF, Moazami N, Rose EA, Smith CR et al (1998) Randomized, doubleblind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. Ann Thorac Surg 1998;65(2): 340-345

    Article  PubMed  CAS  Google Scholar 

  • Atz AM, Lefler AK, Fairbrother DL, Uber WE, Bradley SM (2002) Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises. J Thorac Cardiovasc Surg 124(3): 628-629

    Article  PubMed  Google Scholar 

  • Baumwol J, Macdonald PS, Keogh AM, Kotlyar E, Spratt P et al (2011) Right heart failure and »failure to thrive« after left ventricular assist device: clinical predictors and outcomes. J Heart Lung Transplant 30(8): 888-895

    PubMed  Google Scholar 

  • Cave AC, Manche A, Derias NW, Hearse DJ (1993) Thromboxane A2 mediates pulmonary hypertension after cardiopulmonary bypass in the rabbit. J Thorac Cardiovasc Surg 106(6): 959-967

    PubMed  CAS  Google Scholar 

  • Cohn WE, Demirozu ZT, Frazier OH (2011) Surgical closure of left ventricular outflow tract after left ventricular assist device implantation in patients with aortic valve pathology. J Heart Lung Transplant 30(1): 59-63

    Article  PubMed  Google Scholar 

  • Cohn WE, Frazier OH (2011) The sandwich plug technique: simple, effective, and rapid closure of a mechanical aortic valve prosthesis at left ventricular assist device implantation. J Thorac Cardiovasc Surg 142(2): 455-457

    Article  PubMed  Google Scholar 

  • Dranishnikov N, Stepanenko A, Potapov E, Dandel M, Sinawski H et al (2012) Simultaneous aortic valve replacement in left ventricular assist device recipients: Single-center experience. Int J Artif Organs 35(7): 489-494 doi: 10.5301/ijao.5000102

    PubMed  Google Scholar 

  • Fitzpatrick JR, 3rd, Frederick JR, Hsu VM, Kozin ED, O’Hara ML et al (2008) Risk score derived from pre-operative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant 27(12): 1286-1292

    Article  PubMed  Google Scholar 

  • Fratacci MD, Frostell CG, Chen TY, Wain JC, Jr., Robinson DR, Zapol WM (1991). Inhaled nitric oxide. A selective pulmonary vasodilator of heparin-protamine vasoconstriction in sheep. Anesthesiol 75(6): 990-999

    Article  CAS  Google Scholar 

  • Fukamachi K, McCarthy PM, Smedira NG, Vargo RL, Starling RC, Young JB (1999) Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion. Ann Thorac Surg 68(6): 2181-2184

    Article  PubMed  CAS  Google Scholar 

  • Ghofrani HA, Wiedemann R, Rose F, Olschewski H, Schermuly RT et al (2002) Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 136(7): 515-522

    PubMed  CAS  Google Scholar 

  • Griffith KE, Jenkins E, Stulak J, Paugh T, Pagani FD (2012) Long-term use of the CentriMag Ventricular Assist System as a right ventricular assist device: a case report. Perfusion 27(1): 65-70 Epub 2011 Oct 24

    Article  PubMed  CAS  Google Scholar 

  • Hetzer R, Krabatsch T, Stepanenko A, Hennig E, Potapov EV (2010) Long-term biventricular support with the heartware implantable continuous flow pump. J Heart Lung Transplant 29(7): 822-824

    Article  PubMed  Google Scholar 

  • Hsu PL, Parker J, Egger C, Autschbach R, Schmitz-Rode T, Steinseifer U (2012) Mechanical Circulatory Support for Right Heart Failure: Current Technology and Future Outlook. Artif Organs 36(4): 332-347 Epub 2011 Dec 8

    Article  PubMed  Google Scholar 

  • Kirklin JK, Naftel DC, Stevenson LW, Kormos RL, Pagani FD. et al (2008) INTERMACS database for durable devices for circulatory support: first annual report. J Heart Lung Transplant 27(10): 1065-1072

    Article  PubMed  Google Scholar 

  • Kormos RL, Gasior TA, Kawai A, Pham SM, Murali S et al (1996) Transplant candidate’s clinical status rather than right ventricular function defines need for univentricular versus biventricular support. J Thorac Cardiovasc Surg 111(4): 773-782; discussion 782-783

    Article  PubMed  CAS  Google Scholar 

  • Krabatsch T, Potapov E, Stepanenko A, Schweiger M, Kukucka M et al (2011a) Biventricular circulatory support with two miniaturized implantable assist devices. Circulation 124 (11 Suppl): S179-186

    Article  Google Scholar 

  • Krabatsch T, Schweiger M, Stepanenko A, Drews T, Potapov E et al (2011b) Improvements in implantable mechanical circulatory support systems : literature overview and update Herz 36(7): 622-629

    Article  CAS  Google Scholar 

  • Krishan K, Nair A, Pinney S, Adams DH, Anyanwu AC (2012) Liberal use of tricuspid-valve annuloplasty during left-ventricular assist device implantation. Eur J Cardiothorac Surg 41(1): 213-217

    Article  PubMed  Google Scholar 

  • Kukucka M, Potapov E, Stepanenko A, Weller K, Mladenow A et al (2011a) Acute impact of left ventricular unloading by left ventricular assist device on the right ventricle geometry and function: Effect of nitric oxide inhalation. J Thorac Cardiovasc Surg 141(4): 1009-1014 Epub 2010 Sep 29

    Google Scholar 

  • Kukucka M, Stepanenko A, Potapov E, Krabatsch T, Redlin M et al (2011b) Right-to-left ventricular end-diastolic diameter ratio and prediction of right ventricular failure with continuous-flow left ventricular assist devices. J Heart Lung Transplant 30(1): 64-69 Epub 2010 Oct 29

    Article  Google Scholar 

  • Leather HA, Segers P, Berends N, Vandermeersch E, Wouters PF (2002) Effects of vasopressin on right ventricular function in an experimental model of acute pulmonary hypertension. Crit Care Med 30(11): 2548-2552

    Article  PubMed  CAS  Google Scholar 

  • Lepore JJ, Maroo A, Bigatello LM, Dec GW, Zapol WM et al (2005) Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide. Chest 127(5): 1647-1653

    Article  PubMed  CAS  Google Scholar 

  • Loforte A, Montalto A, Lilla Della Monica P, Musumeci F (2011) Simultaneous temporary CentriMag right ventricular assist device placement in HeartMate II left ventricular assist system recipients at high risk of right ventricular failure. Interact Cardiovasc Thorac Surg 10(6): 847-850

    Article  Google Scholar 

  • Loforte A, Stepanenko A, Potapov E, Dranischnikov N, Schweiger M et al (2012) Temporary versus permanent biventricular support in end-stage refractory biventricular failure. in press

    Google Scholar 

  • Maltais S, Topilsky Y, Tchantchaleishvili V, McKellar SH, Durham LA et al (2012) Surgical treatment of tricuspid valve insufficiency promotes early reverse remodeling in patients with axial-flow left ventricular assist devices. J Thorac Cardiovasc Surg 143(6): 1370-1376 Epub 2011 Aug 11

    Article  PubMed  Google Scholar 

  • Matthews JC, Koelling TM, Pagani FD, Aaronson KD (2008) The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates. J Am Coll Cardiol51(22): 2163-2172

    Article  PubMed  Google Scholar 

  • May-Newman K, Hillen B, Dembitsky W (2006) Effect of left ventricular assist device outflow conduit anastomosis location on flow patterns in the native aorta. Asaio J 52(2): 132-139

    Article  PubMed  Google Scholar 

  • Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R et al (2007) Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation 116(3): 238-248

    Article  PubMed  CAS  Google Scholar 

  • Oz MC, Argenziano M, Catanese KA, Gardocki MT, Goldstein DJ et al (1997) Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation? Circulation 1997;95(7):1844-1852

    CAS  Google Scholar 

  • Pettinari M, Jacobs S, Rega F, Verbelen T, Droogne W, Meyns B (2012) Are right ventricular risk scores useful? Eur J Cardiothorac Surg 2012 Apr 19, [Epub ahead of print]

    Google Scholar 

  • Piacentino V 3rd, Williams ML, Depp T, Garcia-Huerta K, Blue L et al (2011) Impact of tricuspid valve regurgitation in patients treated with implantable left ventricular assist devices. Ann Thorac Surg 91(5):1342-6; discussion 1346-1347

    Article  PubMed  Google Scholar 

  • Potapov EV, Loforte A, Weng Y, Jurmann M, Pasic M et al (2008a) Experience with over 1000 Implanted Ventricular Assist Devices. J Card Surg 23(3): 185-194

    Article  Google Scholar 

  • Potapov E, Meyer D, Swaminathan M, Ramsay M, El Banayosy A et al (2011a) Inhaled nitric oxide after left ventricular assist device implantation: a prospective, randomized, double-blind, multicenter, placebo-controlled trial. J Heart Lung Transplant 30(8): 870-878

    Google Scholar 

  • Potapov EV, Schweiger M, Stepanenko A, Dandel M, Kukucka M et al (2011b) Tricuspid valve repair in patients supported with left ventricular assist devices. Asaio J 57(5): 363-7

    Article  Google Scholar 

  • Potapov EV, Sodian R, Loebe M, Drews T, Dreysse S, Hetzer R (2001) Revascularization of the occluded right coronary artery during left ventricular assist device implantation. J Heart Lung Transplant 20(8): 918-922

    Article  PubMed  CAS  Google Scholar 

  • Potapov EV, Stepanenko A, Dandel M, Kukucka M, Lehmkuhl HB et al (2008b) Tricuspid incompetence and geometry of the right ventricle as predictors of right ventricular function after implantation of a left ventricular assist device. J Heart Lung Transplant 27(12): 1275-1281

    Article  Google Scholar 

  • Puwanant S, Hamilton KK, Klodell CT, Hill JA, Schofield RS et al (2008) Tricuspid annular motion as a predictor of severe right ventricular failure after left ventricular assist device implantation. J Heart Lung Transplant 27(10): 1102-1107

    Article  PubMed  Google Scholar 

  • Rioux JP, Lessard M, De Bortoli B, Roy P, Albert M et al (2009) Pentastarch 10% (250 kDa/0.45) is an independent risk factor of acute kidney injury following cardiac surgery. Crit Care Med 37(4): 1293-1298

    Article  PubMed  CAS  Google Scholar 

  • Saeed D, Kidambi T, Shalli S, Lapin B, Malaisrie SC et al (2011) Tricuspid valve repair with left ventricular assist device implantation: is it warranted? J Heart Lung Transplant 30(5): 530-535

    Article  PubMed  Google Scholar 

  • Stulak JM, Griffith KE, Nicklas JM, Pagani FD (2011) The use of the HeartWare HVAD for long-term right ventricular support after implantation of the HeartMate II device. J Thorac Cardiovasc Surg 142(3): e140-142

    Article  Google Scholar 

  • Viitanen A, Salmenpera M, Heinonen J (1990) Right ventricular response to hypercarbia after cardiac surgery. Anesthesiol 73(3): 393-400

    Article  CAS  Google Scholar 

  • Wan S, LeClerc JL, Vincent JL (1997) Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest 112(3): 676-692

    Article  PubMed  CAS  Google Scholar 

  • Wang Y, Simon MA, Bonde P, Harris BU, Teuteberg JJ et al (2012) Decision tree for adjuvant right ventricular support in patients receiving a left ventricular assist device. J Heart Lung Transplant 31(2): 140-149

    Article  PubMed  Google Scholar 

Literatur zu 9.2

  • Amir O, Bracey AW, Smart FW, Delgado RM 3rd, Shah N, Kar B (2005) A successful anticoagulation protocol for the first HeartMate II implantation in the United States.Tex Heart Inst J 32:399-401

    Google Scholar 

  • Angermayr L, Garrido MV, Busse R (2007) Künstliche Ventrikel bei fortgeschrittener Herzinsuffizinez. Deutsches Institut für Medizinische Dokumentation und Information, Köln

    Google Scholar 

  • Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D et al (2008) Assessing the current role of platelet function testing. Clin Cardiol 31(3 Suppl 1):I10-I16

    Article  Google Scholar 

  • Caccamo M, Eckman P, John R (2011) Current state of ventricular assist devices. Curr Heart Fail Rep 8:91-98

    Article  PubMed  Google Scholar 

  • Christiansen S, Jahn UR, Meyer J, Scheld HH, Van Aken H et al (2000) Anticoagulative management of patients requiring left ventricular assist device implantation and suffering from heparin-induced thrombocytopenia type II. Ann Thorac Surg 69:774-777

    Article  PubMed  CAS  Google Scholar 

  • Drews T, Jurmann M, Michael D, Miralem P, Weng Y, Hetzer R (2008) Differences in pulsatile and non-pulsatile mechanical circulatory support in long-term use. J Heart Lung Transplant 27:1096-1101

    Article  PubMed  Google Scholar 

  • John R, Kamdar F, Liao K, Colvin-Adams M, Miller L et al (2008) Low thromboembolic risk for patients with the Heartmate II left ventricular assist device. J Thorac Cardiovasc Surg 136:1318-1323

    Article  PubMed  Google Scholar 

  • Kalya AV, Tector AJ, Crouch JD, Downey FX, McDonald ML et al (2005) Comparison of Novacor and HeartMate vented electric left ventricular assist devices in a single institution. J Heart Lung Transplant 24:1973-1975

    Article  PubMed  Google Scholar 

  • Körfer R, El-Banayosy A (2004) Mechanische Kreislaufunterstützung - 15 Jahre Erfahrung im Herzzentrum Nordrhein-Westfalen. Dtsch Med Wochenschr 129:800-804

    Article  PubMed  Google Scholar 

  • Liden H, Wierup P, Westerberg M, Nilsson F, Wiklund L (2005) Bridge to heart transplantation with the HeartMate device in Gothenburg, Sweden. Transplant Proc 37:3321-3322

    Article  PubMed  CAS  Google Scholar 

  • Morgan JA, Park Y, Oz MC, Naka Y (2003) Device related infections while on left ventricular assist device support do not adversely impact bridging to transplant or posttransplant survival. ASAIO J 49:748-750

    Article  PubMed  Google Scholar 

  • Morgan JA, John R, Rao V, Weinberg AD, Lee BJ et al (2004) Bridging to transplant with the HeartMate left ventricular assist device: The Columbia Presbyterian 12-year experience. J Thorac Cardiovasc Surg 127:1309-1316

    Article  PubMed  Google Scholar 

  • Panzica MF (2010) Detektion und akustikophysikalische Analyse von mikroembolischen Signalen mittels transkranieller Zweikanal-Dopplersonografie bei terminal herzinsuffizienten Patienten mit pulsatilem linksventrikulären Unerstützungssystem und deren Korrelation zu klinischen und hämostaseologischen Partametern. Inaugural-Dissertaton, Medizinische Fakultät, Westfälische Wilhelms-Universität Münster

    Google Scholar 

  • Pereira NL, Chen D, Kushwaha SS, Park SJ (2010) Discontinuation of antithrombotic therapy for a year or more in patients with continuous-flow left ventricular assist devices. Interact Cardiovasc Thorac Surg 11:503-505

    Article  PubMed  Google Scholar 

  • Schmid C, Jurmann M, Birnbaum D, Colombo T, Falk V et al (2008) Influence of inflow cannula length in axial-flow pumps on neurologic adverse event rate: results from a multi-center analysis. J Heart Lung Transplant 27:253-260

    Article  PubMed  Google Scholar 

  • Siebler M, Nachtmann A, Sitzer M, Steinmetz H (1994) Anticoagulation monitoring and cerebral microemboli detection. Lancet 344:555

    Article  PubMed  CAS  Google Scholar 

  • Slaughter MS, Sobieski MA, Gallagher C, Dia M, Silver MA (2008) Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist device. Tex Heart Inst J 35:245-249

    PubMed  Google Scholar 

  • Strueber M, O’Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM; HeartWare Investigators (2011) Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol 57:1375-1382

    Article  PubMed  Google Scholar 

  • Topkara VK, Dang NC, Martens TP, Cheema FH, Liu JF, Argenziano M, Naka Y (2005) Bridging to transplantation with left ventricular assist devices: outcomes in patients aged 60 years and older. J Thorac Cardiovasc Surg 130:881-882

    Article  PubMed  Google Scholar 

  • Vitali E, Lanfranconi M, Bruschi G, Ribera E, Garatti A et al (2004) Mechanical circulatory support in severe heart failure: single-center experience. Transplant Proc 36:620-622

    Article  PubMed  CAS  Google Scholar 

  • Weitkemper HH, El-Banayosy A, Arusoglu L, Sarnowski P, Körfer R (2004) Mechanical circulatory support: reality and dreams experience of a single center. J Extra Corpor Technol 36:169-173

    PubMed  CAS  Google Scholar 

  • Wieselthaler GM, O Driscoll G, Jansz P, Khaghani A, Strueber M; HVAD Clinical Investigators (2010) Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial. J Heart Lung Transplant 29:1218-1225

    Article  PubMed  Google Scholar 

Literatur zu 9.3

  • Ahmed TM, Cowley JB, Robinson G, Hartley JE, Nicholson AA et al (2010). Long term follow-up of transcatheter coil embolotherapy for major colonic haemorrhage. Colorectal Dis 12: 1013-1017

    Article  PubMed  CAS  Google Scholar 

  • Cannegieter SC, van Der Meer FJ, Briet E Rosendaal FR (1994). Warfarin and aspirin after heart- valve replacement. N Engl J Med 330: 507-508; author reply 508-509

    Article  PubMed  CAS  Google Scholar 

  • Chua AE Ridley LJ (2008). Diagnostic accuracy of CT angiography in acute gastrointestinal bleeding. J Med Imaging Radiat Oncol 52: 333-338

    Article  PubMed  CAS  Google Scholar 

  • Crow S, John R, Boyle A, Shumway S, Liao K et al (2009). Gastrointestinal bleeding rates in recipients of nonpulsatile and pulsatile left ventricular assist devices. J Thorac Cardiovasc Surg 137: 208-215

    Article  PubMed  CAS  Google Scholar 

  • Crow S, Milano C, Joyce L, Chen D, Arepally G et al (2010). Comparative analysis of von Willebrand factor profiles in pulsatile and continuous left ventricular assist device recipients. Asaio J 56(5): 441-445

    Article  PubMed  Google Scholar 

  • Fang JC (2009). Rise of the machines–left ventricular assist devices as permanent therapy for advanced heart failure. N Engl J Med 361: 2282-2285

    Article  PubMed  CAS  Google Scholar 

  • Frazier OH (2000). Mechanical cardiac assistance: historical perspectives. Semin Thorac Cardiovasc Surg 12: 207-219

    PubMed  CAS  Google Scholar 

  • Geffroy Y, Rodallec MH, Boulay-Coletta I, Fulles MC, Ridereau-Zins C, Zins M (2011). Multidetector CT angiography in acute gastrointestinal bleeding: why, when, and how. Radiographics 31: E35-46

    Article  Google Scholar 

  • Geisen U, Heilmann C, Beyersdorf F, Benk C, Berchtold-Herz M et al (2008). Non-surgical bleeding in patients with ventricular assist devices could be explained by acquired von Willebrand disease. Eur J Cardiothorac Surg 33: 679-684

    Article  PubMed  Google Scholar 

  • Gregoric ID, Cohn WE, Frazier OH (2011) Diaphragmatic implantation of the HeartWare ventricular assist device. J Heart Lung Transplant 30: 467-470

    Article  PubMed  Google Scholar 

  • Hayes HM, Dembo LG, Larbalestier R, O’Driscoll G (2010) Management options to treat gastro- intestinal bleeding in patients supported on rotary left ventricular assist devices: a singlecenter experience. Artif Organs 34(9): 703-706

    Article  PubMed  Google Scholar 

  • Jaeckle T, Stuber G, Hoffmann MH, Freund W, Schmitz BL, Aschoff AJ (2008). Acute gastrointestinal bleeding: value of MDCT. Abdom Imaging 33: 285-293

    Article  PubMed  CAS  Google Scholar 

  • John R, Kamdar F, Liao K, Colvin-Adams M, Boyle A, Joyce L (2008). Improved survival and decreasing incidence of adverse events with the HeartMate II left ventricular assist device as bridge-to-transplant therapy. Ann Thorac Surg 86: 1227-1234; discussion 1234-1225

    Article  PubMed  Google Scholar 

  • John R, Lee S (2009) The biological basis of thrombosis and bleeding in patients with ventricular assist devices. J Cardiovasc Transl Res 2: 63-70

    Article  PubMed  Google Scholar 

  • Joyce DD, Crow SS (2011). Bleeding Complications of Continous Flow. Mechanical Circulatory Support. D. L. Joyce, L. D. Joyce and M. Loebe. New York, Mc Graw Hil Medical: 90-92

    Google Scholar 

  • Klovaite J, Gustafsson F, Mortensen SA, Sander K, Nielsen LB (2009). Severely impaired von Willebrand factor-dependent platelet aggregation in patients with a continuous-flow left ventricular assist device (HeartMate II). J Am Coll Cardiol 53: 2162-2167

    Article  PubMed  CAS  Google Scholar 

  • Koster A, Loebe M, Hansen R, Potapov EV, Noon GP et al (2000). Alterations in coagulation after implantation of a pulsatile Novacor LVAD and the axial flow MicroMed DeBakey LVAD. Ann Thorac Surg 70: 533-537

    Article  PubMed  CAS  Google Scholar 

  • Laing CJ, Tobias T, Rosenblum DI, Banker WL, Tseng L, Tamarkin SW (2007). Acute gastrointestinal bleeding: emerging role of multidetector CT angiography and review of current imaging techniques. Radiographics 27: 1055-1070

    Article  PubMed  Google Scholar 

  • Love JW, Jahnke EJ, Zacharias D, Davidson WA, Kidder WR, Luan LL (1980). Calcific aortic stenosis and gastrointestinal bleeding. N Engl J Med 302: 968

    Article  PubMed  CAS  Google Scholar 

  • Massyn MW, Khan SA (2009). Heyde syndrome: a common diagnosis in older patients with severe aortic stenosis. Age Ageing 38: 267-270; discussion 251

    Article  PubMed  CAS  Google Scholar 

  • Meyer AL, Malehsa D, Bara C, Budde U, Slaughter MS et al (2010) Acquired von Willebrand syndrome in patients with an axial flow left ventricular assist device. Circ Heart Fail 3(6):675-81. Epub 2010 Aug 25

    Article  PubMed  Google Scholar 

  • Miller LW, Pagani FD, Russell SD, John R, Boyle AJ et al (2007). Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med 357: 885-896

    Article  PubMed  CAS  Google Scholar 

  • Padia SA, Geisinger MA, Newman JS, Pierce G, Obuchowski NA, Sands MJ (2009). Effectiveness of coil embolization in angiographically detectable versus non-detectable sources of upper gastrointestinal hemorrhage. J Vasc Interv Radiol 20: 461-466

    Article  PubMed  Google Scholar 

  • Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW et al (2001). Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 345: 1435-1443

    Article  PubMed  CAS  Google Scholar 

  • Saito S Nishinaka T (2005). Chronic nonpulsatile blood flow is compatible with normal end-organ function: implications for LVAD development. J Artif Organs 8: 143-148

    Article  PubMed  Google Scholar 

  • Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV et al (2009). Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med 361: 2241-2251

    Article  PubMed  CAS  Google Scholar 

  • Souto JC, Almasy L, Muniz-Diaz E, Soria JM, Borrell M et al (2000). Functional effects of the ABO locus polymorphism on plasma levels of von Willebrand factor, factor VIII, and activated partial thromboplastin time. Arterioscler Thromb Vasc Biol 20: 2024-2028

    Article  PubMed  CAS  Google Scholar 

  • Steinlechner B, Dworschak M, Birkenberg B, Duris M, Zeidler P et al (2009). Platelet dysfunction in outpatients with left ventricular assist devices. Ann Thorac Surg 87: 131-137

    Article  PubMed  Google Scholar 

  • Stern DR, Kazam J, Edwards P, Maybaum S, Bello RA et al(2010) Increased incidence of gastrointestinal bleeding following implantation of the HeartMate II LVAD. J Card Surg 25(3): 352-356

    Article  PubMed  Google Scholar 

  • Sucker C, Feindt P, Scharf RE (2003). Aortic stenosis, von Willebrand factor, and bleeding. N Engl J Med 349: 1773-1774; author reply 1773-1774

    Article  PubMed  CAS  Google Scholar 

  • Uriel N, Pak SW, Jorde UP, Jude B, Susen S et al (2010) Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 56(15):1207-1213 Epub 2010 Jul 2

    Article  Google Scholar 

  • Vincentelli A, Susen S, Le Tourneau T, Six I, Fabre O et al (2003). Acquired von Willebrand syndrome in aortic stenosis. N Engl J Med 349: 343-349

    Article  PubMed  Google Scholar 

  • Weldon DT, Burke SJ, Sun S, Mimura H Golzarian J (2008). Interventional management of lower gastrointestinal bleeding. Eur Radiol 18: 857-867

    Article  PubMed  Google Scholar 

  • Whitlock R, Crowther Mang HJ (2005). Bleeding in cardiac surgery: its prevention and treatment-an evidence-based review. Crit Care Clin 21: 589-610

    Article  PubMed  Google Scholar 

  • Williams RC, Jr. (2004). Aortic stenosis and unexplained gastrointestinal bleeding. Arch Intern Med 164: 679; author reply 679-680

    Article  PubMed  Google Scholar 

  • Yoshida K, Tobe S, Kawata M (2006). Acquired von Willebrand disease type IIA in patients with aortic valve stenosis. Ann Thorac Surg 81: 1114-1116

    Article  PubMed  Google Scholar 

Literatur zu 9.4

  • Ankersmit HJ et al (1999) Activation induced T-cell death and immune dysfunction after implantation of left ventricular assist device. Lancet 354: 550-555

    Article  PubMed  CAS  Google Scholar 

  • Brun-Buisson C et al (2003) The costs of septic syndromes in the intensive care unit and influence of hospital acquired sepsis. Intensive Care Med 29: 1464-1471

    Article  PubMed  Google Scholar 

  • Burke JP (2003) Infection control - A problem for patient safety. New Engl J Med 348: 651-656

    Article  PubMed  Google Scholar 

  • Califano S et al (2012) Left ventricular assist device related infections. Infect Dis Clin North Am 26: 77-87

    Article  PubMed  Google Scholar 

  • Deng MC et al (1999) Left ventricular assist system support is associated with persistent inflammation and temporary immunosuppression. Thorac Cardiovasc Surg 47 (Suppl. 2): 326-331

    Article  PubMed  Google Scholar 

  • Gordon SM et al (2001) Nosocomial bloodstream infections in patients with implantable left ventricular assist devices. Ann Thorac Surg 72: 725-730

    Article  PubMed  CAS  Google Scholar 

  • Harbath S et al (2006) Epidemiologie und Ätiologie schwerer nosokomialer Infektionen. In: Van Aken et al.: Intensivmedizin, Thieme-Verlag, 2. Auflage, Stuttgart, New York

    Google Scholar 

  • Rello J et al (2003) Pneumonia in the intensive care unit. Critical Care Med 31: 2544-2551

    Article  Google Scholar 

  • Sandiumenge A et al (2003) Therapy of ventilator associated pneumonia. A patient based approach based on the ten rules of the «Tarragona-Strategy". Intensive Care Med 29: 876-883

    PubMed  Google Scholar 

  • Tjan TDT et al (2000) Severe wound complications after left ventricular assist device. Ann Thorac Surg 70: 538-541

    Article  PubMed  CAS  Google Scholar 

  • Vincent JL (2003) Nosocomial infections in adult intensive care units. Lancet 361: 2068-2077

    Article  PubMed  Google Scholar 

Literatur zu 9.5

  • Chandrashekhar Y et al. Mitral stenosis (2009) Lancet 374: 1271-1283

    Article  PubMed  CAS  Google Scholar 

  • European Resuscitation Council (2005) Guidelines for Resuscitation 2005. Resuscitation 67 (Suppl. 1): 1-189

    Article  Google Scholar 

  • European Resuscitation Council (2010) European Resuscitation Guidelines for Resuscitation. Resuscitation 81: 1219-1452

    Article  Google Scholar 

  • Litmathe J et al (2006) Predictive risk factors in double-valve replacement (AVR and MVR) compared to isolated aortic valve replacement. Thorac Cardiovasc Surg 54: 459-463

    Article  PubMed  CAS  Google Scholar 

  • Niebauer MJ et al (2001) Management of atrial flutter. Cardiol Rev 9: 253-258

    Article  PubMed  CAS  Google Scholar 

  • Passannante AN (2011) Prevention of atrial fibrillation after cardiac surgery. Curr Opin Anaesthesiol 24: 58-63

    Article  PubMed  Google Scholar 

  • Riley AB (2001) Atrial fibrillation: An epidemic study in the elderly. Expert Rev Cardiovasc Ther 9: 1081-1090

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Boeken, U., Assmann, A., Born, F., Schmid, C. (2013). Komplikationsmanagement. In: Boeken, U., Assmann, A., Born, F., Schmid, C. (eds) Mechanische Herz-Kreislauf-Unterstützung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29408-2_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-29408-2_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-29407-5

  • Online ISBN: 978-3-642-29408-2

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics