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Handheld NMR Systems and Their Applications for Biomolecular Sensing

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Point-of-Care Diagnostics on a Chip

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

We have developed a miniature nuclear magnetic resonance (NMR) system. By combining the physics of NMR with CMOS radio-frequency ICs, we developed a 0.1-kg palm NMR system that is 1,200 times smaller, 1,200 times lighter, and yet 150 times more spin-mass sensitive than a state-of-the-art 120-kg commercial benchtop system. The small NMR system can be used for disease detection and medical diagnostics. It was demonstrated capable of detecting human cancer cells and cancer marker proteins.

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Author information

Authors and Affiliations

  1. Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, TX, USA

    Nan Sun

  2. School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA

    Donhee Ham

Authors
  1. Nan Sun
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  2. Donhee Ham
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Corresponding author

Correspondence to Donhee Ham .

Editor information

Editors and Affiliations

  1. , Department of Bioengineering, University of Pennsylvania, 210 South 33rd Street, Philadelphia, 19104-6321, Pennsylvania, USA

    David Issadore

  2. , School of Engineering, Applied Sciences, Harvard University, Oxford Street 29, Cambridge, 02138, Massachusetts, USA

    Robert M. Westervelt

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Sun, N., Ham, D. (2013). Handheld NMR Systems and Their Applications for Biomolecular Sensing. In: Issadore, D., Westervelt, R. (eds) Point-of-Care Diagnostics on a Chip. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29268-2_8

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  • DOI: https://doi.org/10.1007/978-3-642-29268-2_8

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-29267-5

  • Online ISBN: 978-3-642-29268-2

  • eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)

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