Imaging techniques, such as magnetic resonance imaging (MRI), are described by introducing the mathematical and physical role of the relaxation times T 1 and T 2 and the resonance condition, (Sect. 3.1). An introduction to material theory and continuum mechanics is provided, since they play a key role in the mechanical characterization of human soft tissue materials, (Sect. 3.2). Finite element analysis (FEA) and material parameter identification, provided in Sects. 3.3 and 3.4, give insight into tissue modelling and characterization. Based on experimental findings provided in the literature, biomechanical hypotheses regarding tissue failure are discussed, (Sect. 3.5).