Colloid Flow Control in Microchannels and Detection by Laser Scattering

  • Stefano PagliaraEmail author
  • Catalin Chimerel
  • Dirk G. A. L. Aarts
  • Richard Langford
  • Ulrich F. Keyser
Conference paper
Part of the Progress in Colloid and Polymer Science book series (PROGCOLLOID, volume 139)


We introduce a new approach towards the flow control and detection of colloids in microfluidic specimens. We fabricate hybrid polydimethylsiloxane (PDMS)/glass microfluidic chips equipped with parallel micrometer and sub-micrometer channels with different width and thickness. We image and detect the colloid flow direction through the microchannels by coupling laser-light-scattering in a restricted region of a single channel. We control single polymer colloids by means of a computerized pressure-based flow control system and study the Poiseuille flow through channels with different square cross section. We demonstrate the possibility of in situ sensing populations of colloids with different dimensions down to the sub-100 nm scale.


Wire Array Soft Lithography Laser Scattering Particle Reynolds Number Outlet Reservoir 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Stefano Pagliara
    • 1
    Email author
  • Catalin Chimerel
    • 1
  • Dirk G. A. L. Aarts
    • 2
  • Richard Langford
    • 1
  • Ulrich F. Keyser
    • 1
  1. 1.Cavendish LaboratoryUniversity of CambridgeCambridgeUK
  2. 2.Department of Chemistry, Physical and Theoretical Chemistry LaboratoryUniversity of OxfordOxfordUK

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