Control over the Shell Thickness of Core/Shell Drops in Three-Phase Glass Capillary Devices

  • Goran T. VladisavljevićEmail author
  • Ho Cheung Shum
  • David A. Weitz
Conference paper
Part of the Progress in Colloid and Polymer Science book series (PROGCOLLOID, volume 139)


Monodisperse core/shell drops with aqueous core and poly(dimethylsiloxane) (PDMS) shell of controllable thickness have been produced using a glass microcapillary device that combines co-flow and flow-focusing geometries. The throughput of the droplet generation was high, with droplet generation frequency in the range from 1,000 to 10,000 Hz. The size of the droplets can be tuned by changing the flow rate of the continuous phase. The technique enables control over the shell thickness through adjusting the flow rate ratio of the middle to inner phase. As the flow rate of the middle and inner phase increases, the droplet breakup occurs in the dripping-to-jetting transition regime, with each double emulsion droplet containing two monodisperse internal aqueous droplets. The resultant drops can be used subsequently as templates for monodisperse polymer capsules with a single or multiple inner compartments, as well as functional vesicles such as liposomes, polymersomes and colloidosomes.


Shell Thickness Droplet Breakup Multiple Emulsion Injection Tube Injection Capillary 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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The work was supported by the Engineering and Physical Sciences Research Council (EPSRC) of the United Kingdom (grant reference number: EP/HO29923/1).


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Goran T. Vladisavljević
    • 1
    • 2
    Email author
  • Ho Cheung Shum
    • 3
  • David A. Weitz
    • 4
  1. 1.Department of Chemical EngineeringLoughborough UniversityLoughboroughUK
  2. 2.Vinča Institute of Nuclear SciencesBelgradeSerbia
  3. 3.Department of Mechanical EngineeringUniversity of Hong KongHong KongChina
  4. 4.Department of PhysicsHarvard UniversityCambridgeUSA

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