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Hepatocellular Carcinoma

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Abstract

Three-dimensional conformal radiation therapy (3DCRT) has been the standard technique for hepatocellular carcinoma (HCC). Intensity-modulated radiation therapy (IMRT) may be useful to improve target coverage and for normal organ sparing, especially in the setting of unusual-shaped target volumes. Stereotactic body radiation therapy (SBRT) has been used more recently. Individualized prescription doses are commonly used due to variable liver volume irradiated and proximity to luminal gastrointestinal tissues.

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Further Reading

  • Cheng JC, Chuang VP, Cheng SH, Huang AT, Lin YM, Cheng TI, Yang PS, You DL, Jian JJ, Tsai SY, Sung JL, Horng CF (2000) Local radiotherapy with or without transcatheter arterial chemoembolization for patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 47:435–442

    Article  PubMed  CAS  Google Scholar 

  • Tse RV, Hawkins M, Lockwood G, Kim JJ, Cummings B, Knox J, Sherman M, Dawson LA (2008) Phase I study of individualized stereotactic radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Clin Oncol 26:657–664

    Article  PubMed  Google Scholar 

  • Wang NH, Ji Y, Zeng ZC, Tang ZY, Fan J, Zhou J, Zeng MS, Bi AH, Tan YS (2010) Impact factors for microinvasion in patients with hepatocellular carcinoma: possible application to the definition of clinical tumor volume. Int J Radiat Oncol Biol Phys 76:467–476

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital and Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan, ROC

    Jason Chia-Hsien Cheng M.D., Ph.D.

  2. Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, ROC

    Che-Yu Hsu M.D.

  3. Department of Radiation Oncology, Radiation Medicine Program, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada

    Sameh A. Hashem M.D. & Laura A. Dawson M.D.

Authors
  1. Jason Chia-Hsien Cheng M.D., Ph.D.
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  2. Che-Yu Hsu M.D.
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  3. Sameh A. Hashem M.D.
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  4. Laura A. Dawson M.D.
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Editor information

Editors and Affiliations

  1. , Radiation Oncology, Memorial Sloan-Kettering Cancer Center, York Avenue, Box 22 1275, New York, 10021, New York, USA

    Nancy Y. Lee

  2. NUHS Tower Block, Level 7, Department of Radiation Oncology, National University Cancer Institute, 1E Kent Ridge Road, Singapore, 119228, Singapur, Singapore

    Jiade J. Lu

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© 2013 Springer-Verlag Berlin Heidelberg

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Cheng, J.CH., Hsu, CY., Hashem, S.A., Dawson, L.A. (2013). Hepatocellular Carcinoma. In: Lee, N., Lu, J. (eds) Target Volume Delineation and Field Setup. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28860-9_16

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  • DOI: https://doi.org/10.1007/978-3-642-28860-9_16

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-28859-3

  • Online ISBN: 978-3-642-28860-9

  • eBook Packages: MedicineMedicine (R0)

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