Nevogenesis pp 43-47 | Cite as

Evolution of Nevi

  • Harald KittlerEmail author


According to its original meaning, the term “nevus” has been applied to birthmarks. With regard to melanocytic nevi, the term “nevus” has lost its original meaning and is now being used for congenital and acquired proliferations of melanocytes. The evolution of nevi that are already visible at birth (large congenital nevi or garment nevi) cannot be studied because it is happening “in utero.” The term “tardive congenital nevus” has been applied to melanocytic nevi that are not visible at birth but have a clinical, dermatoscopical, and dermatopathological phenotype similar to nevi that are present at birth. They are significantly smaller than “true” congenital nevi and usually appear in childhood but may appear even as late as in puberty. Their evolution has been studied from an epidemiologic but also from a morphologic point of view [1–5].


Growth Pattern Radial Line Original Meaning Melanocytic Nevus Reticular Pattern 
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  1. 1.
    Scope A, Dusza SW, Marghoob AA, Satagopan JM, Braga Casagrande Tavoloni J, Psaty EL, Weinstock MA, Oliveria SA, Bishop M, Geller AC, Halpern AC. Clinical and dermoscopic stability and volatility of melanocytic nevi in a population-based cohort of children in Framingham school system. J Invest Dermatol. 2011;131(8):1615–21.PubMedCrossRefGoogle Scholar
  2. 2.
    Scope A, Marghoob AA, Dusza SW, Satagopan JM, Agero AL, Benvenuto-Andrade C, Lieb JA, Weinstock MA, Oliveria SA, Geller AC, Halpern AC. Dermoscopic patterns of naevi in fifth grade children of the Framingham school system. Br J Dermatol. 2008;158(5):1041–9. Epub 2008 Mar 20.PubMedCrossRefGoogle Scholar
  3. 3.
    LaVigne EA, Oliveria SA, Dusza SW, Geller AC, Halpern AC, Marghoob AA. Clinical and dermoscopic changes in common melanocytic nevi in school children: the Framingham school nevus study. Dermatology. 2005;211(3):234–9.PubMedCrossRefGoogle Scholar
  4. 4.
    Kittler H, Pehamberger H, Wolff K, Binder M. Follow-up of melanocytic skin lesions with digital epiluminescence microscopy: patterns of modifications observed in early melanoma, atypical nevi, and common nevi. J Am Acad Dermatol. 2000;43(3):467–76.PubMedCrossRefGoogle Scholar
  5. 5.
    Kittler H, Seltenheim M, Dawid M, Pehamberger H, Wolff K, Binder M. Frequency and characteristics of enlarging common melanocytic nevi. Arch Dermatol. 2000;136(3):316–20.PubMedCrossRefGoogle Scholar
  6. 6.
    Nino M, Brunetti B, Delfino S, Brunetti B, Panariello L, Russo D. Spitz nevus: follow-up study of 8 cases of childhood starburst type and proposal for management. Dermatology. 2009;218(1):48–51. Epub 2008 Oct 2.PubMedCrossRefGoogle Scholar
  7. 7.
    Argenziano G, Zalaudek I, Ferrara G, Lorenzoni A, Soyer HP. Involution: the natural evolution of pigmented Spitz and reed nevi? Arch Dermatol. 2007;143(4):549–51.PubMedGoogle Scholar
  8. 8.
    Argenziano G, Agozzino M, Bonifazi E, Broganelli P, Brunetti B, Ferrara G, Fulgione E, Garrone A, Zalaudek I. Natural evolution of Spitz nevi. Dermatology. 2011;222(3):256–60.PubMedCrossRefGoogle Scholar

Copyright information

© Springer- Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of DermatologyMedical University of ViennaViennaAustria

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