Nevogenesis pp 145-153 | Cite as

Disappearance of Melanocytic Nevi

  • Vitaly Terushkin
  • Ashfaq A. MarghoobEmail author
  • Alon Scope
  • Rainer Hofmann-Wellenhof


Nevus involution is a common phenomenon, but the mechanisms responsible for this process are currently not well characterized. With the development of noninvasive imaging technologies, such as dermoscopy and reflectance confocal microscopy, we have begun to appreciate distinct morphological features that develop, or in some case, disappear during nevus involution. In this chapter, we describe several dermoscopic patterns of disappearing nevi and attempt to illustrate their potential mechanisms using evidence from the literature and personal experience.


Melanin Synthesis Papillary Dermis Melanocytic Nevus Reflectance Confocal Microscopy Nevus Cell 
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Copyright information

© Springer- Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Vitaly Terushkin
    • 1
  • Ashfaq A. Marghoob
    • 2
    Email author
  • Alon Scope
    • 3
    • 4
    • 5
  • Rainer Hofmann-Wellenhof
    • 6
  1. 1.Dermatology ServiceMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Memorial Sloan-Kettering Skin Cancer CenterNew YorkUSA
  3. 3.Dermatology ServiceMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  4. 4.Department of DermatologySheba Medical CenterRamat GanIsrael
  5. 5.Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael
  6. 6.Department of DermatologyMedical University of GrazGrazAustria

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