Advanced Spectroscopy Technique for Biomedicine

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


This chapter presents an overview of the applications of optical spectroscopy in biomedicine. We focus on the optical design aspects of advanced biomedical spectroscopy systems, Raman spectroscopy system in particular. Detailed components and system integration are provided. As examples, two real-time in vivo Raman spectroscopy systems, one for skin cancer detection and the other for endoscopic lung cancer detection, and an in vivo confocal Raman spectroscopy system for skin assessment are presented. The applications of Raman spectroscopy in cancer diagnosis of the skin, lung, colon, oral cavity, gastrointestinal tract, breast, and cervix are summarized.


Raman Spectrum Raman Spectroscopy Spectroscopy System Raman Probe Digital Micromirror Device 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Our Raman spectroscopy work was supported by the Canadian Cancer Society, the Canadian Dermatology Foundation, the Canadian Institutes of Health Research, the BC Hydro Employees’ Community Service Fund, and the VGH and UBC Foundation. The authors wish to thank Dr. Harvey Lui and Dr. David I. McLean for helpful discussions. The authors acknowledge Dr. Zhiwei Huang, Dr. Michael Short, and Ms. Tracy Wang for providing some of the figures.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Imaging Unit - Integrative Oncology DepartmentBritish Columbia Cancer Agency Research CenterVancouverCanada
  2. 2.Photomedicine Institute, Department of Dermatology and Skin ScienceUniversity of British Columbia & Vancouver Coastal Health Research InstituteVancouverCanada

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