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Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer pp 163–170Cite as

Circulating Endothelial Cells and Circulating Endothelial Progenitors

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 195))

Abstract

The roles of circulating endothelial cells (CECs) and circulating endothelial progenitors (CEPs) are currently being investigated in several diseases including cancer and metastases development. Preclinical and clinical data suggest that CEC enumeration might be useful to identify patients who might benefit from anti-angiogenic treatments while CEPs seem to have a “catalytic” role in different steps of cancer progression and recurrence after therapy. The definition of CEC and CEP phenotypes and the standardization of CEC and CEP enumeration procedures are highly warranted to use these cells as biomarkers in clinical trials in oncology, and to compare results from different studies.

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Author information

Authors and Affiliations

  1. Laboratory of Hematology-Oncology, European Institute of Oncology, via Ripamonti 435, 20141, Milan, Italy

    Patrizia Mancuso, Angelica Calleri & Francesco Bertolini

Authors
  1. Patrizia Mancuso
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  2. Angelica Calleri
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  3. Francesco Bertolini
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Corresponding author

Correspondence to Francesco Bertolini .

Editor information

Editors and Affiliations

  1. , Breast Cancer Translational Res. Lab., Institut Jules Bordet, Boulevard de Waterloo 125, Brussels, 1000, Belgium

    Michail Ignatiadis

  2. , Breast Cancer Translational Res. Lab., Institut Jules Bordet, Boulevard de Waterloo 125, Brussels, 1000, Belgium

    Christos Sotiriou

  3. Zentrum für Experimentelle Medizin, Inst. Tumorbiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany

    Klaus Pantel

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Mancuso, P., Calleri, A., Bertolini, F. (2012). Circulating Endothelial Cells and Circulating Endothelial Progenitors. In: Ignatiadis, M., Sotiriou, C., Pantel, K. (eds) Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer. Recent Results in Cancer Research, vol 195. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28160-0_14

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  • DOI: https://doi.org/10.1007/978-3-642-28160-0_14

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-28159-4

  • Online ISBN: 978-3-642-28160-0

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