Abstract
The imaging technique of optical coherence tomography (OCT) has opened a unique world in the area of ophthalmology, specifically in imaging the human retina. The findings based on the use of OCT have brought new knowledge of the retina and the changes that occur in the retina that previously have not been available in vivo. In addition to the current uses of OCT, new fields of application have recently emerged, and it is believed that additional ones will gain maturity in the near future. In this chapter, we demonstrate the potential use of OCT in the assessment of changes on the blood–retinal barrier and in the neuronal tissue related to the aging process.
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Acknowledgments
The authors would like to thank Dr. Melissa Horne and Carl Zeiss Meditec (Dublin, CA, USA) for their support on obtaining access to OCT data and AIBILI - The Centre for Clinical Trials (CEC) technicians for their support in managing data, working with patients, and performing scans. This study is supported in part by the Fundação para a Ciência e a Tecnologia (FCT) under the research project PTDC/SAU-BEB/103151/2008 and program COMPETE (FCOMP-01-0124-FEDER-010930).
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Bernardes, R., Cunha-Vaz, J. (2012). Evaluation of the Blood–Retinal Barrier with Optical Coherence Tomography. In: Bernardes, R., Cunha-Vaz, J. (eds) Optical Coherence Tomography. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27410-7_8
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DOI: https://doi.org/10.1007/978-3-642-27410-7_8
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