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Adaptive Optics in Ocular Optical Coherence Tomography

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Optical Coherence Tomography

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

Adaptive optics (AO) is a technology for correcting aberrations in real time. When applied to the human eye, it has the potential of perfect imaging, from an optical perspective, the retina. Once aberrations from the eye have been compensated, theoretical resolution achievable in the living retina is 2–3 μm. Therefore, individual cells and most of the morphological structures on the retina could be in principle imaged. Optical coherence tomography (OCT) has benefitted from this novel technique since 2004. The singularities of OCT, mainly the confocal detection and the mandatory use of broadband spectral light sources, imposes particular methods when applying AO. In a few years, many advances in the combination of AO with OCT have emerged. The in vivo images obtained with that modality have unveiled amazing details of the intraretinal tissue. In this chapter, both the theory and the practice of merging AO with OCT, with special emphasis on ultrahigh-resolution (UHR) OCT, will be presented and discussed.

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Acknowledgements

Some of the figures of the current chapter, particularly those pertaining retina images, show results obtained in close collaboration with W. Drexler and his group, who are acknowledged. This work has been financially supported by “Ministerio de Educación y Ciencia,” Spain (grant FIS2007-64765), and “Fundación Séneca,” Murcia, Spain (grant 04524/GERM/06).

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  1. Laboratorio de Óptica, Centro de Investigación en Óptica y Nanofísica (CiOyN), Universidad de Múrcia, Campus de Espinardo, E-30071, Murcia, Spain

    Enrique Josua Fernández & Pablo Artal

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  1. Enrique Josua Fernández
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    Rui Bernardes

  2. , Faculty of Medicine, University of Coimbra, Azinhaga Sta. Comba, Celas, Coimbra, 3000-548, Portugal

    José Cunha-Vaz

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Fernández, E.J., Artal, P. (2012). Adaptive Optics in Ocular Optical Coherence Tomography. In: Bernardes, R., Cunha-Vaz, J. (eds) Optical Coherence Tomography. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27410-7_10

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