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Investigation of Improved Double Quantum Coherence Filter for Localized Detection of Brain γ-Aminobutyric Acid at 1.5T

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Recent Advances in Computer Science and Information Engineering

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 129))

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Abstract

A single voxel proton point-resolved spectroscopy (PRESS)-localized double quantum filter was introduced at 1.5T clinical scanner for the detection of Brainγ-Aminobutyric Acid (GABA). This method selectively prepares GABA into a double quantum coherence state and suppresses all other resonances at 3.01ppm in each single scan. In phantom experiments, the optimal echo time, the editing efficiency and the degree of suppression of uncoupled resonances were examined after numerical analysis of the editing performance. Excellent GABA signal retention at 3.01ppm was achieved and the spectral editing efficiency was approximately 40%. The suppressed Cr ratio and suppressed NAA ratio were 1118:1 at 3.0ppm and 1815:1 at 2.02ppm respectively.

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Author information

Authors and Affiliations

  1. Engineering College, Shantou University, Shantou, China

    Huang Huang, Daiyue Zeng & Yaowen Chen

  2. Medical Imaging Department, The 2nd Affiliated Hospital of Shantou University, Shantou, China

    Zhiwei Shen, Yan Lin & Renhua Wu

  3. Applied Science Laboratory, GE Healthcare China, Beijing, China

    Hao Shen

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  1. Huang Huang
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  2. Daiyue Zeng
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  3. Yaowen Chen
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  4. Zhiwei Shen
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  5. Yan Lin
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  6. Renhua Wu
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  7. Hao Shen
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Editor information

Editors and Affiliations

  1. , College of Communication Engineering, Jilin University, Room 313, Building No.1, Changchun, Nanhu Avenue 5372, Jilin, 130012, China, People's Republic

    Zhihong Qian

  2. , Department of Electrical Engineering, The University of Mississippi, Anderson Hall 314, Mississippi, 38677, Mississippi, USA

    Lei Cao

  3. , Department of Electrical and Computer En, Naval Postgraduate School, Rm. 452 Spanagel Bldg. 232, Dyer Road 833, Monterey, 93943-5121, California, USA

    Weilian Su

  4. , Faculty of Computing, London Metropolitan University, Holloway Road 166-220, London, N7 8DB, United Kingdom

    Tingkai Wang

  5. , College of Software, Changchun University of Science and Tech, Changchun, Jilin, 130022, China, People's Republic

    Huamin Yang

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© 2012 Springer-Verlag GmbH Berlin Heidelberg

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Huang, H. et al. (2012). Investigation of Improved Double Quantum Coherence Filter for Localized Detection of Brain γ-Aminobutyric Acid at 1.5T. In: Qian, Z., Cao, L., Su, W., Wang, T., Yang, H. (eds) Recent Advances in Computer Science and Information Engineering. Lecture Notes in Electrical Engineering, vol 129. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25778-0_6

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  • DOI: https://doi.org/10.1007/978-3-642-25778-0_6

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-25777-3

  • Online ISBN: 978-3-642-25778-0

  • eBook Packages: EngineeringEngineering (R0)

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