Abstract
The commercialization of miniaturized systems for bioanalytical applications demands fabrication methods which allow the generation of disposable devices which on the one hand fulfill requirements with respect to high geometrical precision and compatibility with the chemistries involved and, on the other hand, offer manufacturing cost which allows these devices to become low-cost disposables. We present a technology chain for the realization of such devices using polymer replication methods and subsequent back-end processing steps. Due to the usual complex set of requirements faced during the development of a bioanalytical system utilizing microfluidic functionality, development strategies for their implementation will be discussed. Practical examples of devices for the use in biotechnological applications will be presented.
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Acknowledgments
Parts of this work were funded by the German Federal Ministry of Education and Research (BMBF) (grant no. 13N9556) and managed by the Projektträger VDI-Technologiezentrum Physikalische Technologien. We would like to acknowledge the kind support by all partners of the joint project
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Becker, H., Gärtner, C. (2012). Polymeric Microfluidic Devices for High Performance Optical Imaging and Detection Methods in Bioanalytics. In: Fritzsche, W., Popp, J. (eds) Optical Nano- and Microsystems for Bioanalytics. Springer Series on Chemical Sensors and Biosensors, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25498-7_10
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DOI: https://doi.org/10.1007/978-3-642-25498-7_10
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