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Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases pp 481–494Cite as

PET-CT in Bone and Joint Diseases

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Abstract

Except for acute trauma such as fracture, contusion or sprain, and physical injury such as electric or thermal burn or freezing, the damage to cells in disease starts at the molecular or chemical level followed by anatomical response. Accordingly, a truly early diagnosis of a disease requires an appropriate means to detect preanatomical change, and PET is a modality that meets this requirement. PET, the latest high technology nuclear imaging modality, has been shown to be a potent tool for the imaging of early metabolic change and simultaneous quantitative assessment of the change, and is widely used in many economically developed countries. Its indications include the diagnosis, staging and restaging, therapy planning, assessment of therapeutic effects, recurrence monitoring, and prognostication of neoplastic conditions and inflammations. Until recently, PET suffered from a crucial inherent problem of inaccuracy in localizing detected lesions because of suboptimal anatomical information. The problem, however, has been successfully overcome by hybridizing PET with CT. In addition, the production and distribution of special radiopharmaceuticals have also become tremendously improved so that they are now available without major difficulty in everyday practice.

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  1. Yong-Whee Bahk

    Present address: Depart. of Nuclear Med. and Radiology, Sun Ae General Hospital, Seoul, Korea, Republic of

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  1. Department of Radiology and Nuclear Medicine, The Catholic University of Korea, Seoul, Korea

    Sung-Hoon Kim

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Bahk, YW., Kim, SH. (2013). PET-CT in Bone and Joint Diseases. In: Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25144-3_21

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  • DOI: https://doi.org/10.1007/978-3-642-25144-3_21

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