Abstract
Malignant bone tumors are either primary or metastatic in nature. The high sensitivity and accuracy of 99mTc-MDP bone scintigraphy in diagnosing bone metastasis were established as long ago as 1961 (Fleming et al. 1961) (Fig. 1.2). In contrast, its usefulness in the investigation of primary bone tumors, both malignant and benign, appears not to be fully appreciated. The main reason is the low diagnostic yield of conventional planar bone scintigraphy; this is true. However, recognizing the fact that the magnified images of pinhole scintigraphy can depict anatomy in amazing detail along with unique metabolic information, a number of primary tumors and tumor-like diseases of bone have become among the most important and challenging indications for bone scanning.
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Bahk, YW., Bahk, WJ. (2013). Malignant Tumors of Bone. In: Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25144-3_17
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