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Notfälle in der Dermatoonkologie

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Zusammenfassung

Bei der tumorinduzierten Hyperkalzämie kommt es zur tumorzellbedingten bzw. paraneoplastischen Freisetzung von Zytokinen, die – unabhängig von vorliegenden Knochenmetastasen – eine gesteigerte Kalziummobilisierung aus dem Skelett sowie eine vermehrte Kalziumrückresorption in der Niere bewirkt.

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Literatur

  • Boles JM, Dutel JL, Briere J, Mialon P, Robasckiewicz M, Garre M, Briere J (1984) Acute renal failure caused by extreme hyperphosphatemia after chemotherapy of an acute lymphoblastic leukemia. Cancer 53:2425–2429

    Article  PubMed  CAS  Google Scholar 

  • Brown PD, Brown CA, Pollock BE, Gorman DA, Foote RL (2002) Stereotactic radiosurgery for patients with „radioresistant“ brain metastases. Neurosurgery 51:656–665

    PubMed  Google Scholar 

  • Buchsbaum JC, Suh JH, Lee SY, Chidel MA, Greskovich JF, Barnett GH (2002) Survival by radiation therapy oncology group recursive partitioning analysis class and treatment modality in patients with brain metastases from malignant melanoma: a retrospective study. Cancer 94:2265–2272

    Article  PubMed  Google Scholar 

  • Bugelski PJ, Achuthanandam R, Capocasale RJ, Treacy G, Bouman-Thio E (2009) Monoclonal antibody-induced cytokine-release syndrome. Expert Rev Clin Immunol 5:499–521

    Article  PubMed  CAS  Google Scholar 

  • Burchardi H, Larsen R, Schuster HP, Suter PM (2004) Die Intensivmedizin. Springer, Berlin Heidelberg New York, S. 596

    Book  Google Scholar 

  • Busam KJ, Wolchok J, Jungbluth AA, Chapman P (2004) Diffuse melanosis after chemotherapy-induced tumor lysis syndrome in a patient with metastatic melanoma. J Cutan Pathol 31:274–280

    Article  PubMed  Google Scholar 

  • Cairo MS, Bishop M (2004) Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 127:3–11

    Article  PubMed  Google Scholar 

  • Deppermann KM, Kreuser ED (2006) Intrakavitäre Therapie bei malignem Perikarderguss. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie. Springer, Berlin Heidelberg New York, S. 1055–1060

    Chapter  Google Scholar 

  • Dhir V, Arya V, Malav IC, Suryanarayanan BS, Gupta R, Dey AB (2007) Idiopathic systemic capillary leak syndrome (SCLS): case report and systematic review of cases reported in the last 16 years. Intern Med 46:899–904

    Article  PubMed  Google Scholar 

  • Dillman RO, Hendrix CS (2003) Unique aspects of supportive care using monoclonal antibodies in cancer treatment. Support Cancer Ther 1:38–48

    Article  PubMed  Google Scholar 

  • Dubrey S, Grocott-Mason R, Mittal T, Burke M (2008) Massive cardiac invasion by amelanotic melanoma with obstructive clinical features. Postgrad Med J 84:163–166

    Article  PubMed  CAS  Google Scholar 

  • Garbe C, Hauschild A, Volkenandt M et al. (2005) Deutsche Leitlinie: Malignes Melanom. In: Garbe C (Hrsg) Interdisziplinäre Leitlinien zur Diagnostik und Behandlung von Hauttumoren. Thieme, Stuttgart, S 23–55

    Google Scholar 

  • Gaspar L, Scott C, Rotman M, Asbell S, Phillips T, Wasserman T, McKenna WG, Byhardt R (1997) Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys 37:745–751

    Article  PubMed  CAS  Google Scholar 

  • Goldman SC, Holcenberg JS, Finklestein JZ, Hutchinson R, Kreissman S, Johnson FL, Tou C, Harvey E, Morris E, Cairo MS (2001) A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis. Blood 97:2998–3003

    Article  PubMed  CAS  Google Scholar 

  • Hansel TT, Kropshofer H, Singer T, Mitchell JA, George AJ (2010) The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov 9:325–338

    Article  PubMed  CAS  Google Scholar 

  • Jidar K, Ingen-Housz-Oro S, Beylot-Barry M, Paul C, Chaoui D, Sigal-Grinberg M, Morel P, Dubertret L, Bachelez H (2009) Gemcitabine treatment in cutaneous T-cell lymphoma: a multicentre study of 23 cases. Br J Dermatol 161:660–663

    Article  PubMed  CAS  Google Scholar 

  • Kirova YM, Chen J, Rabarijaona LI, Piedbois Y, Le Bourgeois JP (1999) Radiotherapy as palliative treatment for metastatic melanoma. Melanoma Res 9:611–613

    Article  PubMed  CAS  Google Scholar 

  • Mahajan A, Nirmal S, English MW, Jenney ME, Lazda ED (2002) Acute tumor lysis syndrome in Hodgkin disease Med Pediatr Oncol 39:69–70

    Article  PubMed  Google Scholar 

  • Major P, Lortholary A, Hon J, Abdi E, Mills G, Menssen HD, Yunus F, Bell R, Body J, Quebe-Fehling E, Seaman J (2001) Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. J Clin Oncol 19:558–567

    PubMed  CAS  Google Scholar 

  • Mornex F, Thomas L, Mohr P, Hauschild A, Delaunay MM, Lesimple T, Tilgen W, Bui BN, Guillot B, Ulrich J, Bourdin S, Mousseau M, Cupissol D, Bonneterre ME, De Gislain C, Bensadoun RJ, Clavel M (2003) A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma. Melanoma Res 13:97–103

    Article  PubMed  CAS  Google Scholar 

  • Nakayama-Ichiyama S, Yokote T, Iwaki K, Hiraoka N, Hirata Y, Oka S, Akioka T, Miyoshi T, Takayama A, Nishiwaki U, Masuda Y, Tsuji M, Hanafusa T (2011) Hypercalcaemia induced by tumour-derived parathyroid hormone-related protein and multiple cytokines in diffuse large B cell lymphoma, not otherwise specified. Pathology 43:742–745

    Article  PubMed  Google Scholar 

  • Perez-Gala S, Delgado-Jimenez Y, Goiriz R, Fraga J, Garcia-Diez A, Fernandez-Herrera J (2006) Cytokine-release syndrome related to rituximab limited to lesions and excision scars of lesions of primary cutaneous lymphoma 142:1516–1517

    Google Scholar 

  • Pollock BE, Brown PD, Foote RL, Stafford SL, Schomberg PJ (2003) Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease. J Neurooncol 61:73–80

    Article  PubMed  Google Scholar 

  • Possinger K, Schmid P (2006) Hyperkalzämie. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie. Springer, Berlin, S. 1109–1113

    Chapter  Google Scholar 

  • Raizer JJ, Hwu WJ, Panageas KS, Wilton A, Baldwin DE, Bailey E, von Althann C, Lamb LA, Alvarado G, Bilsky MH, Gutin PH (2008) Brain and leptomeningeal metastases from cutaneous melanoma: survival outcomes based on clinical features. Neuro Oncol 10(2):199–207

    Article  PubMed  Google Scholar 

  • Rate WR, Solin LJ, Turrisi AT (1988) Palliative radiotherapy for metastatic malignant melanoma: brain metastases, bone metastases, and spinal cord compression. Int J Radiat Oncol Biol Phys 15:859–864

    Article  PubMed  CAS  Google Scholar 

  • Schleucher N, Schmoll HJ, Harstrick (2006) Tumorlysesyndrom. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie. Springer, Berlin Heidelberg New York, S. 1114–1117

    Chapter  Google Scholar 

  • Schwartz RN, Stover L, Dutcher J (2002) Managing toxicities of high-dose interleukin-2. Oncology 11 (Suppl 13):11–20

    Google Scholar 

  • Sparano DM, Ward RP (2011) Pericarditis and pericardial effusion: management update. Curr Treat Options Cardiovasc Med 13:543–555

    Article  PubMed  Google Scholar 

  • Trefzer U, Pelzer K, Hofmann MA, Sterry W (2006) Parathyroid hormone-related protein-induced hypercalcaemia in metastatic melanoma. J Eur Acad Dermatol Venereol 20:346–347

    Article  PubMed  CAS  Google Scholar 

  • Wing M (2008) Monoclonal antibody first dose cytokine release syndromes-mechanisms and prediction. J Immunotoxicol 5:11–15

    Article  PubMed  CAS  Google Scholar 

  • Wössmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A (2003) Incidence of tumor lysis syndrome in children with advanced stage Burkitt’s lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase. Ann Hematol 82:160–165

    PubMed  Google Scholar 

  • Wroński M, Arbit E (2000) Surgical treatment of brain metastases from melanoma: a retrospective study of 91 patients. J Neurosurg; 93:9–18

    Article  PubMed  Google Scholar 

  • Yang B, Lu XC, Yu RL, Chi XH, Zhang WY, Zhu HL, Yuan J, Zhao P (2012) Diagnosis and Treatment of Rituximab-Induced Acute Tumor Lysis Syndrome in Patients With Diffuse Large B-Cell Lymphoma. Am J Med Sci, im Druck

    Google Scholar 

  • Yang H, Rosove MH, Figlin RA (1999) Tumor lysis syndrome occurring after the administration of rituximab in lymphoproliferative disorders: high-grade non-Hodgkin’s lymphoma and chronic lymphocytic leukemia. Am J Hematol 62:247–50

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Lucie Heinzerling .

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Heinzerling, L., Hartmann, A., Hund, M., Schuler, G. (2014). Notfälle in der Dermatoonkologie. In: Medikamentöse Tumortherapie in der Dermato-Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24837-5_6

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  • DOI: https://doi.org/10.1007/978-3-642-24837-5_6

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-24836-8

  • Online ISBN: 978-3-642-24837-5

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