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Chronisch-entzündliche Darmerkrankungen (CED)

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Pädiatrische Gastroenterologie, Hepatologie und Ernährung

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Zusammenfassung

Inzidenz und Prävalenz der CED haben in den vergangenen zwei Jahrzehnten sowohl im Kindesalter als auch bei Erwachsenen zugenommen. Verglichen mit dem Zeitraum 1990–1992 wurde in Schweden ein signifikanter Anstieg der Inzidenz des M. Crohn von 1,7 erkrankten Kindern pro 100.000 Einwohner auf 8,4 / 100.000 in den Jahren 1999–2001 beobachtet. Die zunehmende Inzidenz der CED bei Kindern und Jugendlichen ist nicht die Folge eines zunehmend früheren Krankheitsbeginns, sondern Ausdruck einer zunehmenden Inzidenz in allen Altersklassen. Aus Großbritannien, Australien, Schweden und den USA zeigen Studien Folgendes: Die Inzidenz des M. Crohn liegt zwischen 1,3 und 6 pädiatrischen Patienten pro 100.000 Einwohner. Die klinische Manifestation der CED erfolgt bei bis zu 30 % aller Patienten bereits vor dem 18. Lebensjahr. Vereinzelte Fallberichte und kleinere Studien zeigen, dass ein Erkrankungsbeginn bereits in den ersten Lebensjahren möglich ist. Heyman et al. (2005) berichten, dass etwa 60 % der bis zum Alter von 18 Jahren erkrankten Kinder bereits vor ihrem 12. Lebensjahr erkranken und 9 % bereits vor dem 5. Lebensjahr.

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Authors and Affiliations

  1. Klinik für allgemeine Pädiatrie, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland

    Michael Friedt Dr.

  2. Abteilung Gastroenterologie und Ernährung, Universitäts-Kinderkliniken, Kinderspital Zürich, Steinwiesstr. 75, 8032, Zürich, Schweiz

    Christian P. Braegger Prof. Dr.

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  1. Michael Friedt Dr.
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  2. Christian P. Braegger Prof. Dr.
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  1. Zentrum für Kinder- und Jugendmedizin, Christliches Kinderhospital Osnabrück, Johannisfreiheit 1, 49074, Osnabrück, Deutschland

    Burkhard Rodeck Priv.-Doz. Dr.

  2. Abteilung Allgemeine Pädiatrie und Neonatalogie, Universitätsklinikum Gießen und Marburg GmbH, Zentrum für Kinderheilkunde und Jugendmedizin, Feulgenstr. 12, 35392, Gießen, Deutschland

    Klaus-Peter Zimmer Prof. Dr.

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Friedt, M., Braegger, C.P. (2013). Chronisch-entzündliche Darmerkrankungen (CED). In: Rodeck, B., Zimmer, KP. (eds) Pädiatrische Gastroenterologie, Hepatologie und Ernährung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24710-1_11

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