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Microfluidic System as a Tool for Magnetic Separation of Human Cells with Diagnostic Relevance

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Magnetic Particle Imaging

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 140))

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Abstract

A new microfluidic system was realized by means of a specially designed chip from silicon and glass. Magnetic disks were located above and below this chip. The transportation, mixing, incubation and the chip based separation procedure of the cell-magnetic bead suspension is caused by pumps and the rotation of permanent magnets arranged outside the chip.

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Authors and Affiliations

  1. Institute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, Heilbad-Heiligenstadt, Thuringia, 37308, Germany

    J. Schemberg, K. Lemke, G. Gastrock & J. Metze

  2. IBA GmbH, Rudolf-Wissell-Str. 28, Göttingen, Lower Saxony, 37079, Germany

    J. Bertram

  3. Intros GmbH, Rudolf-Diesel Str.3, Heilbad-Heiligenstadt, Thuringia, 37308, Germany

    M. Hottenrott

  4. Abteilung Transfusionsmedizin, Universitätsmedizin Göttingen, Stiftung Öffentlichen Rechts, Robert-Koch-Straße 40, Göttingen, Lower Saxony, 37075, Germany

    T. Legler

  5. GeSiM mbH, Bautzner Landstrasse 45, Großerkmannsdorf, Saxony, 01454, Germany

    S. Howitz

Authors
  1. J. Schemberg
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  2. J. Bertram
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  3. M. Hottenrott
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  4. T. Legler
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  5. S. Howitz
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  6. K. Lemke
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  7. G. Gastrock
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  8. J. Metze
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Corresponding author

Correspondence to J. Schemberg .

Editor information

Editors and Affiliations

  1. , Institute of Medical Engineering, University of Luebeck, Ratzeburger Allee 160, Luebeck, 23538, Germany

    Thorsten M. Buzug

  2. Forschungslaboratorien, Philips Technologie GmbH, Röntgenstr. 24-26, Hamburg, 22335, Germany

    Jörn Borgert

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© 2012 Springer-Verlag GmbH Berlin Heidelberg

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Schemberg, J. et al. (2012). Microfluidic System as a Tool for Magnetic Separation of Human Cells with Diagnostic Relevance. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_11

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