Abstract
Optimal control of an Intensive Care Unit (ICU) metabolic model from nonlinear control point of view is presented in the current paper. The transformation of a clinically validated nonlinear model into a series of integrators via exact linearization and asymptotic output tracking is performed. Both methods need the value of the state variables; therefore Kalman-filter extended for nonlinear systems is applied. Finally, linear optimal LQ method is applied on the ICU model handled with differential geometric approach. Results are demonstrated on input data recorded in actual clinical environment.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kovács, L., Szalay, P., Benyó, B., Chase, J.G. (2011). Optimal Tight Glycaemic Control Supported by Differential Geometric Methods. In: Jobbágy, Á. (eds) 5th European Conference of the International Federation for Medical and Biological Engineering. IFMBE Proceedings, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23508-5_91
Download citation
DOI: https://doi.org/10.1007/978-3-642-23508-5_91
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-23507-8
Online ISBN: 978-3-642-23508-5
eBook Packages: EngineeringEngineering (R0)