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Organ Printing: A Novel Tissue Engineering Paradigm

  • F. Marga
  • K. Jakab
  • C. Khatiwala
  • B. Shephard
  • S. Dorfman
  • G. Forgacs
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 37)

Abstract

We present a novel tissue engineering technology, which utilizes bioprinting, the automated delivery of bio-ink units, multicellular aggregates of defined composition, into biopaper, a biocompatible support environment. Biological structures, tissues and organoids, form post-printing, by morphogenetic processes akin to those utilized in early embryonic development, such as tissue fusion and cell sorting. We demonstrate the technology by building vascular grafts.

Keywords

Tissue engineering bioprinting bioreactor morphogenesis early development 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • F. Marga
    • 1
  • K. Jakab
    • 1
  • C. Khatiwala
    • 2
  • B. Shephard
    • 2
  • S. Dorfman
    • 2
  • G. Forgacs
    • 1
  1. 1.Physics DepartmentUniversity of MissouriColumbiaUSA
  2. 2.Organovo, Inc.San DiegoUSA

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