Organ Printing: A Novel Tissue Engineering Paradigm
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We present a novel tissue engineering technology, which utilizes bioprinting, the automated delivery of bio-ink units, multicellular aggregates of defined composition, into biopaper, a biocompatible support environment. Biological structures, tissues and organoids, form post-printing, by morphogenetic processes akin to those utilized in early embryonic development, such as tissue fusion and cell sorting. We demonstrate the technology by building vascular grafts.
KeywordsTissue engineering bioprinting bioreactor morphogenesis early development
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