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Intraoperative Adjuncts in Thyroid and Parathyroid Surgery

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Surgery of the Thyroid and Parathyroid Glands

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Abstract

Parathyroid hormone (PTH) is cleared from the blood in an early rapid phase with a half-life variously reported as 1.68–21.5 min in patients with normal renal function. The accuracy of various assays for intact (1–84) PTH is high. These facts justify the concept of PTH measurement prior to and after excision of abnormal parathyroid gland(s) in patients with primary hyperparathyroidism (PHPT) as a means to confirm or refute biochemical ‘cure’ and the removal of all hyperfunctioning parathyroid glands – IOPTH, a biochemical ‘frozen section. The technique was reported to be used by 68% of members of the International Association of Endocrine Surgeons in 2002.

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Authors and Affiliations

  1. Department of Endocrine Surgery, Royal Hallamshire Hospital Sheffield, Glossop Road, Sheffield, S10 2JF, UK

    Barney Harrison M.D.

  2. Department of Surgery, University Hospital of Geneva, 24, rue de Général Dufour, CH-1211, Geneva, Switzerland

    Frédéric Triponez M.D.

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  1. Barney Harrison M.D.
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  2. Frédéric Triponez M.D.
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Correspondence to Barney Harrison M.D. .

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  1. Chairman, Department of Surgery, University Hospital Basel, Spitalstr. 21, Basel, 4031, Switzerland

    Daniel Oertli

  2. Yale-New Haven Hospital, Department of Surgery, Yale University School of Medicine, Cedar Street 330FMB 102, New Haven, CT, 06520-8062, USA

    Robert Udelsman

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Harrison, B., Triponez, F. (2012). Intraoperative Adjuncts in Thyroid and Parathyroid Surgery. In: Oertli, D., Udelsman, R. (eds) Surgery of the Thyroid and Parathyroid Glands. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23459-0_28

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