Abstract
The Present study envisages pharmaceutical utility of Assam Bora rice as biopolymeric excipient in drug delivery. The sustained release potential from the proposed matrix backbone was investigated through in vitro dissolution studies of microbeads prepared by an industrially feasible conventional ionotropic gelation method using the blends of pregelatinized Bora rice along with sodium alginate, as per SUPAC-MR guidelines. The prepared beads were characterized for surface morphology, drug-polymer compatibility, mucoadhesion and other pharmacotechnical parameters. The outcomes of studies have demonstrated that Assam Bora rice holds the promise of being used as a drug release modulator in the drug carrier systems.
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Sachan, N., Pushkar, S., Ghosh, S. (2012). Evaluation of Assam Bora Rice as a Natural Mucoadhesive Matrixing Agent for Controlled Drug Delivery. In: Khemani, L., Srivastava, M., Srivastava, S. (eds) Chemistry of Phytopotentials: Health, Energy and Environmental Perspectives. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23394-4_35
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DOI: https://doi.org/10.1007/978-3-642-23394-4_35
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