Orocervical Region

  • Francisco de Asís Bravo-RodríguezEmail author
  • Rocío Díaz-Aguilera
Part of the Learning Imaging book series (LEARN)


Adenoid cystic carcinoma (ACC) is a malignant epithelial tumor developing in the salivary glands. Although the tumor may be located in the parotid and submandibular glands, the minor salivary glands are the most common place of origin of this carcinoma and ACC accounts for approximately 33% of all malignancies of the minor salivary glands. The tumor occurring in these glands has a worse prognosis than when it occurs in the major glands. This carcinoma is more frequently found in patients between the fourth and seventh decades of life, predominantly in the fifth decade, and shows a slight predominance in females (ratio female:male is 3:2). ACC has a marked tendency to invade nerve tissue and this condition occurs in up to 60% of cases. Specifically, it involves the nerve sheaths, with a typical pattern of skip metastasis, covering a wide locoregional area of the nerves peripheral to the primary tumor. Cervical metastases are rare and occur in only 8–13% of patients. Distant metastases may present in up to 50% of ACC patients during the course of the disease, with the lungs and liver as the most common sites.


Parotid Gland Adenoid Cystic Carcinoma Pleomorphic Adenoma Laryngeal Carcinoma Minor Salivary Gland 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Francisco de Asís Bravo-Rodríguez
    • 1
    Email author
  • Rocío Díaz-Aguilera
    • 2
  1. 1.Diagnostic and Therapeutics NeuroradiolgyReina Sofía University HospitalCórdobaSpain
  2. 2.Department of RadiologyAlto Guadalquivir HospitalAndújar, JaénSpain

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