Adenovirus Epithelial Keratitis Caused by Various Serotypes (Ad3, 4, and 7)

Abstract

Of the seven patients included in this chapter, each represents a bit of clinical reality with differential diagnostic considerations. In six of them, the infection was verified by virological laboratory. In the last one (Case 7), the diagnosis was clinical, based on findings and a knowledge of a close relative with a verified adenovirus infection. Intrafamilial spread occurred also in cases 2 and 3. In Case 1, Ad8 infection was considered because of a history of a recent journey to a region where Ad8 is endemic, but the tests showed Ad3. In Case 2, a combination of red eye and general symptoms implied pharyngoconjunctival fever, but a primary HSV infection, often not thought of at the patient’s age because rare, could have given similar initial symptoms; a careful observation of the morphology revealed the true cause.