Skip to main content
SpringerLink
Log in
Book cover

International Conference on Information Processing in Computer-Assisted Interventions

IPCAI 2011: Information Processing in Computer-Assisted Interventions pp 113–121Cite as

Correlating Clinical Scores with Anatomical Electrodes Locations for Assessing Deep Brain Stimulation

  • Conference paper

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 6689))

Abstract

Movement disorders in patients with Parkinson’s disease may require functional surgery, when medical therapy isn’t effective. In Deep Brain Stimulation (DBS), electrodes are implanted within the brain to stimulate deep structures such as SubThalamic Nucleus (STN). This paper describes successive steps for constructing digital atlases gathering patient’s location of electrode contacts and clinical scores. Three motor and three neuro-psychological scores were integrated in the study. Correlations between active contacts localization and clinical data were carried out using an adapted Hierarchical Ascendant Classification and have enabled the extraction of clusters aiming to suggest optimum sites for therapeutic STN DBS. The postero-superior region has been found to be effective for motor score improvement whereas the antero-inferior region revealed noticeable neuro-psychological scores deterioration. Comparison with existing results has shown that such atlases are very promising for understanding phenomena better.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Benabid, A.L., Krack, P., Benazzouz, A., Limousin, P., Koudsie, A., Pollak, P.: Deep brain stimulation of the subthalamic nucleus for Parkinson’s disease: methodologic aspects and clinical criteria. Neurology 55, 40–44 (2000)

    Google Scholar 

  2. Rodriguez-Oroz, M.C., Rodriguez, M., Guridi, J., Mewes, K., Chockkman, V., Vitek, J., DeLong, M.R., Obeso, J.A.: The subthalamic nucleus in parkinson’s disease: somatotopic organization and physiological. Brain 124(9), 1777–1790 (2001)

    Article  Google Scholar 

  3. Parsons, T.D., Rogers, S.A., Braayen, A.J., Woods, S.P., Troster, A.I.: Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson’s disease: a meta-analysis. Lancet. Neurol. 5, 578–588 (2006)

    Article  Google Scholar 

  4. Biseul, I., Sauleau, P., Haegelen, C., Trebon, P., Drapier, D., Raoul, S., Drapier, S., Lallement, F., Rivier, I., Lajat, Y., Verin, M.: Fear recognition is impaired by subthalamic nucleus stimulation in Parkinson’s disease. Neuropsychologia 43, 1054–1059 (2005)

    Article  Google Scholar 

  5. Houeto, J., Mesnage, V., Mallet, L., Pillon, B., Gargiulo, M., du Moncel, S., Bonnet, A., Pidoux, B., Dormont, D., Cornu, P., Agid, Y.: Behavioural disorders, Parkinson’s disease and subthalamic stimulation. J. Neurol. Neurosurg. Psychiatry 72, 701–707 (2002)

    Article  Google Scholar 

  6. St-Jean, P., Sadikot, A.F., Collins, L., Clonda, D., Kasrai, R., Evans, A.C., Peters, T.M.: Automated atlas integration and interactive three-dimensional visualization tools for planning and guidance in functional neurosurgery. IEEE Trans. on Med. Imaging 17(5), 854–866 (1998)

    Article  Google Scholar 

  7. D’Haese, P.F., Cetinkaya, E., Konrad, P.E., Kao, C., Dawant, B.M.: Computer-aided placement of deep brain stimulators: From planning to intraoperative. IEEE TMI 24(11), 1469–1478 (2005)

    Google Scholar 

  8. D’Haese, P.F., Pallavaram, S., Li, R., Remple, M.S., Kao, C., Neimat, J.S., Konrad, P.E., Dawant, B.M.: CranialVault and its CRAVE tools: A clinical computer assistance system for deep brain stimulation (DBS) therapy. Med. Image Anal., Ahead of print (2010)

    Google Scholar 

  9. Guo, T., Parrent, A.G., Peters, T.M.: Surgical targeting accuracy analysis of six methods for subthalamic nucleus deep brain stimulation. Computer Aided Surgery 12(6), 325–334 (2007)

    Article  Google Scholar 

  10. Pallavaram, S., Dawant, B.M., Remple, M., Neimat, J.S., Kao, C., Konrad, P.E., D’Haese, P.F.: Effect of brain shift on the creation of functional atlases for deep brain stimulation surgery. Int. J. Comp. Assist Radiol. Surg. 5(3), 221–228 (2009)

    Article  Google Scholar 

  11. Coupe P, Yger P, Prima S, Hellier P, Kervrann C, Barillot C. An Optimized Blockwise Non Local Means Denoising Filter for 3D Magnetic Resonance Images. IEEE TMI 24(4), 425-441 (2008)

    Google Scholar 

  12. Mangin, J.F.: Entropy minimization for automatic correction of intensity non uniformity. In: Proc. of the IEEE Workshop on Math. Method in Biomed. Image Analysis, MMBIA 2000, Hilton Head Island, pp. 162–169 (2000)

    Google Scholar 

  13. Pollo, C., Villemure, J.G., Vingerhoets, F., Ghika, J., Maeder, P., Meuli, R.: Magnetic resonance artefact induced by the electrode activa 3389: an in vitro and in vivo study. Acta Neurochirurgica 146(2), 161–164 (2004)

    Article  Google Scholar 

  14. Lalys, F., Haegelen, C., Ferre, J.C., El-Ganaoui, O., Jannin, P.: Construction and assessment of a 3T MRI brain template. NeuroImage 49, 345–354 (2010)

    Article  Google Scholar 

  15. Lalys, F., Haegelen, C., Abadie, A., Jannin, P.: Post-operative assessment in Deep Brain Stimulation based on multimodal images: registration workow and validation. In: Proceedings of SPIE, vol. 7261 (2009)

    Google Scholar 

  16. Fahn, Y., Elton, R.: Unified Parkinson’s disease rating scale. In: Fahn, S., Marsden, C., Calne, D., Goldstein, M. (eds.) Recent Developments in Parkinson’s Disease, vol. 2, pp. 153–163. Macmillan, Florham Park (1987)

    Google Scholar 

  17. Schwab, R.S., England Jr., A.: Projection techniques for evaluating surgery in Parkinson’s Disease, pp. 152–157 (1968)

    Google Scholar 

  18. Hoehn, M., Yahr, M.: Parkinsonism: onset, progression and mortality. Neurology 17(5), 427–442 (1967)

    Article  Google Scholar 

  19. Stroop, J.R.: Studies of interference in serial verbal reactions. Journal of Experimental Psychology 18, 643–661 (1935)

    Article  Google Scholar 

  20. Troyer, A.K., Moscovitch, M., Winocur, G., Leach, L., Freedman, M.: Clustering and switching on verbal fluency tests in Alzheimer’s and Parkinson’s disease. J. Int. Neuropsycholog. Soc. 4(2), 137–143 (1998)

    Article  Google Scholar 

  21. Lanotte, M.M., Rizzone, M., Bergamasco, B., Faccani, G., Melcarne, A., Lopiano, L.: Deep Brain Stimulation of the subthalamic nucleus: anatomical, neurophysiological, and outcome correlations with the effects of stimulation. J. Neurol Neurosurg. Psychiatry 72, 53–58 (2002)

    Article  Google Scholar 

  22. Theodosopoulos, P.V., Marks, W.J., Christine, C., Starr, P.A.: Locations of movement-related cells in the human subthalamic nucleus in parkinson’s disease. Movement Disorders 18(7), 791–798 (2003)

    Article  Google Scholar 

  23. Saint-Cyr, J.A., Trépanier, L.L., Kumar, R., Lozano, A.M., Lang, A.E.: Neuropsychological consequences of chronic stimulation of the subthalamic nucleus in Parkinson’s disease. Brain 123, 2091–2108 (2000)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. U746, Faculty of Medicine CS 34317, INSERM, F-35043, Rennes, France

    Florent Lalys, Claire Haegelen, Alexandre Abadie & Pierre Jannin

  2. INRIA, VisAGeS Unit/Project, F-35042, Rennes, France

    Florent Lalys, Claire Haegelen, Alexandre Abadie & Pierre Jannin

  3. CNRS, UMR 6074, IRISA, University of Rennes I, F-35042, Rennes, France

    Florent Lalys, Claire Haegelen, Alexandre Abadie & Pierre Jannin

  4. Department of Neurosurgery, Pontchaillou University Hospital, F-35043, Rennes, France

    Claire Haegelen

Authors
  1. Florent Lalys
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Claire Haegelen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Alexandre Abadie
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pierre Jannin
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Dept. of Computer Science, The Johns Hopkins University, MD 21218, Baltimore, USA

    Russell H. Taylor

  2. Department of Computing, Imperial College London, SW7 2BZ, London, UK

    Guang-Zhong Yang

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Lalys, F., Haegelen, C., Abadie, A., Jannin, P. (2011). Correlating Clinical Scores with Anatomical Electrodes Locations for Assessing Deep Brain Stimulation. In: Taylor, R.H., Yang, GZ. (eds) Information Processing in Computer-Assisted Interventions. IPCAI 2011. Lecture Notes in Computer Science, vol 6689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21504-9_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-21504-9_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-21503-2

  • Online ISBN: 978-3-642-21504-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics

Search

Navigation