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Dopplersonographie in Geburtshilfe und Gynäkologie pp 89–103Cite as

Plazentationsstörungen und feto-maternale Erkrankungen

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Zusammenfassung

Von Plazentationsstörungen spricht man, wenn eine fehlerhaft angelegte Plazenta im weiteren Verlauf Erkrankungen der Mutter nach sich zieht (Präeklampsie PE, schwangerschaftsinduzierte Hypertonie SIH, HELLP-Syndrom, vorzeitige Plazentalösung) und/oder der Fetus betroffen ist: intrauterine Wachstumsrestriktion (IUGR) und Plazentainsuffizienz sowie intrauteriner Fruchttod (IUFD).

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Literatur

  • Albaiges G, Missfelder-Lobos H, Lees C, Parra M, Nicolaides KH (2000) One-stage screening for pregnancy complications by color Doppler assessment of the uterine arteries at 23 weeks' gestation. Obstet Gynecol. 96(4): 55964

    Article  CAS  PubMed  Google Scholar 

  • Akolekar R, Zaragoza E, Poon LC, Pepes S, Nicolaides KH (2008) Maternal serum placental growth factor at 11+0 to 13+6 weeks of gestation in the prediction of pre-eclampsia. Ultrasound Obstet Gynecol. 32(6): 7329

    Article  CAS  PubMed  Google Scholar 

  • Akolekar R, Syngelaki A, Beta J, Kocylowski R, Nicolaides KH (2009) Maternal serum placental protein 13 at 11-13 weeks of gestation in preeclampsia. Prenat Diagn. 29(12): 11038

    Article  PubMed  Google Scholar 

  • Aquilina J, Barnett A, Thompson O, Harrington K (2000) Comprehensive analysis of uterine artery flow velocity waveforms for the prediction of pre-eclampsia. Ultrasound Obstet Gynecol. 16: 16370

    Article  CAS  PubMed  Google Scholar 

  • Arabin B (1990) Doppler flow measurements in uteroplacental and fetal vessels. Pathophysiological and clinical significance. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  • Arduini D, Rizzo G, Romanini C, Mancuso S (1987) Utero-placental blood flow velocity waveforms as predictors of pregnancy-induced hypertension. Eur J Obstet Gynecol Reprod Biol 26: 335341

    Article  CAS  PubMed  Google Scholar 

  • Ay E, Kavak ZN, Elter K, Gokaslan H, Pekin T (2005) Screening for preeclampsia by using maternal serum inhibin A, activin A, human chorionic gonadotropin, unconjugated estriol, and alpha-fetoprotein levels and uterine artery Doppler in the second trimester of pregnancy. Aust N Z J Obstet Gynaecol. 45(4): 2838

    Article  PubMed  Google Scholar 

  • Baschat AA, Kasdaglis TL, Aberdeen GW, Turan OM, Kopelman JL, Atlas R, Jenkins C, Blitzer M, Harman CR (2009) Serum pentraxin-3 levels at 11 to 14 weeks' gestation: association with maternal and placental characteristics. Am J Obstet Gynecol. 201(3):298.e16

    Article  Google Scholar 

  • Bewley S, Cooper D, Campbell S (1991) Doppler investigation of uteroplacental blood flow resistance in the second trimester: a screening study for preeclampsia and intrauterine growth retardation. Br J Obstet Gynecol 98: 871879

    Article  CAS  Google Scholar 

  • Bower S, Bewley S, Cambell S (1993) Improved prediction of preeclampsia by two-stage screening of uterine arteries using the early diastolic notch and color Doppler imaging. Obstet Gynecol 82: 7883

    CAS  PubMed  Google Scholar 

  • Brosens I, Robertson WB, Dixon HG (1967) The physiological response of the vessels of the placental bed to normal pregnancy. J Pathol Bacteriol 93: 569

    Google Scholar 

  • Brosens IA, Robertson WB, Dixon HG (1972) The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Ann 1: 177191

    CAS  Google Scholar 

  • Brosens IA (1977) Morphological changes in the utero-placental bed in pregnancy hypertension. Clin Obstet Gynaecol 4: 573593

    CAS  PubMed  Google Scholar 

  • Bujold E, Morency AM, Roberge S, Lacasse Y, Forest JC, Giguère Y (2009) Acetylsalicylic acid for the prevention of preeclampsia and intra-uterine growth restriction in women with abnormal uterine artery Doppler: a systematic review and meta-analysis. J Obstet Gynaecol Can 31: 818826

    PubMed  Google Scholar 

  • Campbell S, Pearce JMF, Hackett G, Cohen-Overbeck T, Hernandez J (1986) Qualitative assessment of uteroplacental blood flow: Early screening test for high-risk pregnancies. Obstet Gynecol 68: 649653

    CAS  PubMed  Google Scholar 

  • Campbell S, Black R, Lees C, Armstrong V, Peacock J (2000) Doppler ultrasound of the maternal uterine arteries: disappearance of abnormal waveforms and relation to birthweight and pregnancy outcome. Acta Obstet Gynecol Scand 79: 631634

    CAS  PubMed  Google Scholar 

  • Carbillon L, Largillière C, Perrot N, Tigaizin A, Cynober E, Uzan M (2003) Hémodynamique utéroplacentaire et pratique du Doppler utérin à 12 semaines d’aménorrhée. Gynécologie Obstétrique & Fertilité 31: 378381

    Article  CAS  Google Scholar 

  • Carbillon L, Uzan M, Largillière C, Perrot N, Tigaizin A, Paries J, Pharazien I, Uzan S (2004) Prospective evaluation of uterine artery flow velocity waveforms at 12-14 and 22-24 weeks of gestation in relation to pregnancy outcomes and birth weight. Fetal Diagn Ther 19: 381384

    Article  CAS  PubMed  Google Scholar 

  • Carbillon L (2006) First trimester uterine artery Doppler abnormalities predict subsequent intrauterine growth restriction Am J Obstet Gynecol 195(6): e3

    Google Scholar 

  • Chambers SE, Johnstone FD, Muir BB, Hoskins P, Haddad NG, McDicken WN (1988) The effects of placental site on the arcuate artery flow velocity waveform. J Ultrasound Med 7: 671673

    CAS  PubMed  Google Scholar 

  • Cowans NJ, Spencer K (2007) First-trimester ADAM12 and PAPP-A as markers for intrauterine fetal growth restriction through their roles in the insulin-like growth factor system. Prenat Diagn. 27(3): 26471

    Article  CAS  PubMed  Google Scholar 

  • Cowans NJ, Stamatopoulou A, Matwejew E, von Kaisenberg CS, Spencer K (2010) First-trimester placental growth factor as a marker for hypertensive disorders and SGA. Pren Diagn 30: 56570

    Article  CAS  Google Scholar 

  • Dugoff L, Lynch AM, Cioffi-Ragan D, Hobbins JC, Schultz LK, Malone FD, D’Alton ME, FASTER Trial Research Consortium (2005) First trimester uterine artery Doppler abnormalities predict subsequent intrauterine growth restriction. Am J Obstet Gynecol 193: 12081212

    Article  Google Scholar 

  • Fendel H, Jörn H, Fendel M, Scheffen I, Funk A (1992) Doppler-Flussprofile bei hypertensiven Erkrankungen und Diabetes mellitus in der Schwangerschaft. Gynäkologe 25: 297305

    CAS  PubMed  Google Scholar 

  • Fleischer A, Schulman H, Farmakides G, Bracero L, Grunfeld L, Rochelson B, Koenigsberg M (1986) Uterine artery Doppler velocimetry in pregnant women with hypertension. Am J Obstet Gynecol 154: 806813

    Article  CAS  PubMed  Google Scholar 

  • Födisch HJ (1977) Neue Erkenntnisse über die Orthologie und Pathologie der Plazenta. Enke, Stuttgart

    Google Scholar 

  • Giguère Y, Charland M, Bujold E, Bernard N, Grenier S, Rousseau F, Lafond J, Légaré F, Forest JC (2010) Combining biochemical and ultrasonographic markers in predicting preeclampsia: a systematic review. Clin Chem 56: 361375

    Article  PubMed  Google Scholar 

  • Giles WB, Trudinger BJ, Baird PJ (1985) Fetal umbilical artery flow velocity waveforms and placental resistance: pathological correlation. Br J Obstet Gynecol 92: 3138

    Article  CAS  Google Scholar 

  • Gomez O, Martinez J, Figueras F, Del Rio M, Borobio V, Puerto B, Coll O, Cararach V, Vanrell J (2005) Uterine artery Doppler at 11-14 weeks of gestation to screen for hypertensive disorders and associated complications in an unselected population. Ultrasound Obstet Gynecol 26: 490494

    Article  CAS  PubMed  Google Scholar 

  • Grab D, Hütter W, Sterzik K, Terinde R (1992) Reference values for resistance index and pulsatility index of uteroplacental Doppler flow velocity waveforms based on 612 uneventful pregnancies. Gynecol Obstet Invest 34: 8287

    Article  CAS  PubMed  Google Scholar 

  • Grab D (1994) Dopplersonographie. In: Risikofaktoren der kindlichen Entwicklung: Klinik und Perspektiven. Steinkopff, Darmstadt

    Google Scholar 

  • Gudmundsson S, Marsal K (1988) Ultrasound Doppler evaluation of uteroplacental and fetoplacental circulation in pre-eclampsia. Arch Gynecol Obstet 243: 199206

    Google Scholar 

  • Hanretty KP, Primrose MH, Neilson JP, Whittle M (1989) Pregnancy screening by Doppler uteroplacental and umbilical artery waveforms. Br J Obstet Gynecol 96: 11631167

    Article  CAS  Google Scholar 

  • Harrington K, Cooper D, Lees C, Hecher K, Campbell S (1996) Doppler ultrasound of the uterine arteries: the importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby. Ultrasound Obstet Gynecol. 7(3): 1828

    Article  CAS  PubMed  Google Scholar 

  • Harrington K, Goldfrad C, Carpenter RG, Campbell S (1997) Transvaginal uterine and umbilical artery Doppler examination of 12-16 weeks and the subsequent development of pre-eclampsia and intrauterine growth retardation. Ultrasound Obstet Gynecol 9: 94100

    Article  CAS  PubMed  Google Scholar 

  • Harrington K, Fayyad A, Thakur V, Aquilina J (2004) The value of uterine artery Doppler in the prediction of uteroplacental complications in multiparous women. Ultrasound Obstet Gynecol. 23(1): 505

    Article  CAS  PubMed  Google Scholar 

  • Hofstaetter C, Dubiel M, Gudmundsson S, Marsal K (1996) Uterine artery color Doppler assisted velocimetry and perinatal outcome. Acta Obstet Gynecol Scand 75: 612619

    Article  CAS  PubMed  Google Scholar 

  • Hollis B, Mavrides E, Campbell S, Tekay A, Thilaganathan B (2001) Reproducibility and repeatability of first-trimester uterine artery Doppler. Ultrasound Obstet Gynecol 18: 593597

    Article  CAS  PubMed  Google Scholar 

  • Hollis B, Prefumo F, Bhide A, Rao S, Thilaganathan B (2003) Firsttrimester uterine artery blood flow and birth weight. Ultrasound Obstet Gynecol 22: 373376

    Article  CAS  PubMed  Google Scholar 

  • Kaufmann P, Black S, Huppertz B (2003) Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod. 69(1): 17

    Article  CAS  PubMed  Google Scholar 

  • Khalil A, Cowans NJ, Spencer K, Goichman S, Meiri H, Harrington K (2010) First trimester markers for the prediction of pre-eclampsia in women with a priori high risk. Ultrasound Obstet Gynecol. 35(6): 671679

    CAS  PubMed  Google Scholar 

  • Kurdi W, Campbell S, Aquilina J, England P, Harrington K (1998) The role of color Doppler imaging of the uterine arteries at 20 weeks' gestation in stratifying antenatal care. Ultrasound Obstet Gynecol. 12(5): 33945

    Article  CAS  PubMed  Google Scholar 

  • Lees C (2000) Uterine artery Doppler: time to establish the ground rules. Ultrasound Obstet Gynecol 16: 607609

    Article  CAS  PubMed  Google Scholar 

  • Liao AW, Toyama J, Costa V, Ramos C, Brizot M, Zugaib M (2009) Correlation between the Doppler velocimetry findings of the uterine arteries during the first and second trimesters of pregnancy. Rev Assoc Med Bras. 55(2): 197200

    Article  PubMed  Google Scholar 

  • Matwejew E, Cowans NJ, Stamatopoulou A, Spencer K, von Kaisenberg CS (2010) Maternal serum ADAM-12 as a potential marker for different adverse pregnancy outcomes. Fetal Diagn Ther 27: 3239

    Article  CAS  PubMed  Google Scholar 

  • Martin AM, Bindra R, Curcio P, Cicero S, Nicolaides KH (2001) Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 18: 583586

    Article  CAS  PubMed  Google Scholar 

  • Melchiorre K, Leslie K, Prefumo F, Bhide A, Thilaganathan B (2009) First-trimester uterine artery Doppler indices in the prediction of small-for-gestational age pregnancy and intrauterine growth restriction. Ultrasound Obstet Gynecol. 33(5): 52429

    Article  CAS  PubMed  Google Scholar 

  • Onwudiwe N, Yu CK, Poon LC, Spiliopoulos I, Nicolaides KH.Prediction of pre-eclampsia by a combination of maternal history, uterine artery Doppler and mean arterial pressure (2008) Ultrasound Obstet Gynecol. 32(7):877–83.

    Google Scholar 

  • Papageorghiou AT, Yu CK, Bindra R, Pandis G, Nicolaides KH (2001) Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation. Ultrasound Obstet Gynecol. 18(5): 44149

    Article  CAS  PubMed  Google Scholar 

  • Pearce JMF, Campbell S, Cohen-Overbeck T, Hackett G, Hernandez J, Roysten JP (1988) References, ranges and sources of variation for indices of pulsed Doppler flow velocity waveforms from the uertoplacental and fetal circulation. Br J Obstet Gynecol 95: 248256

    Article  CAS  Google Scholar 

  • Pijnenborg R, Bland JM, Robertson WB, Brosens I (1983) Uteroplacental arterial changes related to interstitial trophoblast migration in early pregnancy. Placenta 4: 397414

    Article  CAS  PubMed  Google Scholar 

  • Pijnenborg R, Ball E, Bulmer JN, Hanssens M, Robson SC, Vercruysse L (2006) In vivo analysis of trophoblast cell invasion in the human. Methods Mol Med. 122:1144

    PubMed  Google Scholar 

  • Plasencia W, Maiz N, Poon L, Yu C, Nicolaides KH (2008) Uterine artery Doppler at 11+0 to 13+6 weeks and 21+0 to 24+6 weeks in the prediction of pre-eclampsia. Ultrasound Obstet Gynecol. 32(2): 13846

    Article  CAS  PubMed  Google Scholar 

  • Poon LC, Zaragoza E, Akolekar R, Anagnostopoulos E, Nicolaides KH (2008) Maternal serum placental growth factor (PlGF) in small for gestational age pregnancy at 11+0 to 13+6 weeks of gestation. Prenat Diagn. 28(12): 111015

    Article  PubMed  Google Scholar 

  • Poon LC, Maiz N, Valencia C, Plasencia W, Nicolaides KH (2009a) Firsttrimester maternal serum pregnancy-associated plasma protein-A and pre-eclampsia. Ultrasound Obstet Gynecol. 33(1): 2333

    Article  CAS  PubMed  Google Scholar 

  • Poon LC, Kametas NA, Maiz N, Akolekar R, Nicolaides KH (2009b) First-trimester prediction of hypertensive disorders in pregnancy. Hypertension. 53(5): 8128

    Google Scholar 

  • Prefumo F, Sebire NJ, Thilaganathan B (2004) Decreased endovascular trophoblast invasion in first trimester pregnancies with high-resistance uterine artery Doppler indices. Hum Reprod 19: 206209

    Article  CAS  PubMed  Google Scholar 

  • Prefumo F, Fratelli N, Ganapathy R, Bhide A, Frusca T, Thilaganathan B (2008) First trimester uterine artery Doppler in women with previous pre-eclampsia. Acta Obstet Gynecol Scand. 87(12): 127175

    Article  PubMed  Google Scholar 

  • Robertson WB, Brosens I, Dixon G (1975) Uteroplacental vascular pathology. Eur J Obstet Gynecol Reprod Biol. 5(1-2): 4765

    Article  CAS  PubMed  Google Scholar 

  • Schaffer H, Lassmann R, Staudach A, Steiner H (1989) Aussagewert qualitativer Doppler-Untersuchungen in der Schwangerschaft. Ultraschall Klin Prax 4: 815

    Google Scholar 

  • Schulman H, Ducey J, Farmakides G, Guzman E, Winter D, Penny B, Chi-Lee BS (1987) Uterine artery Doppler velocimetry: The significance of divergent systolic/diastolic ratios. Am J Obstet Gynecol 157: 15391542

    Article  CAS  PubMed  Google Scholar 

  • Stamatopoulou A, Cowans NJ, Matwejew E, von Kaisenberg CS, Spencer K (2010) Placental protein-13 and pregnancy associated plasma protein-A as first trimester screening markers for hypertensive disorders and IUGR. J Hypert Pregn, in press

    Google Scholar 

  • Standardkommission der Arbeitsgemeinschaft Dopplersonographie und maternofetale Medizin (AGDMFM) (1996) Standards in der Perinatalmedizin - Doppler-Sonographie in der Schwangerschaft. Geburtshilfe Frauenheilkd 56: 6973

    Google Scholar 

  • Steel SA, Pearce JM, McParland P, Chamberlain GV (1990) Early Doppler ultrasound screening in prediction of hypertensive disorders or pregnancy. Lancet 335: 15481551

    Article  CAS  PubMed  Google Scholar 

  • Thaler I, Weiner Z, Itskovitz J (1992) Systolic or diastolic notch in uterine artery blood flow velocity waveforms in hypertensive pregnant patients: relationship to outcome. Obstet Gynecol 80 :277282

    CAS  PubMed  Google Scholar 

  • Todros T, Ferrazzi E, Arduini D et al (1995) Performance of Doppler Ultrasonography as a screening test in low risk pregnancies: Results of a multicenter study. J Ultrasound Med 14: 343348

    CAS  PubMed  Google Scholar 

  • Trudinger BJ, Giles WB, Cook CM (1985) Uteroplacental blood flow velocity-time waveforms in normal and complicated pregnancy. Br J Obstet Gynecol 92: 3945

    Article  CAS  Google Scholar 

  • Trudinger BJ, Cook CM (1990) Doppler umbilical and uterine flow waveforms in severe pregnancy hypertension. Br J Obstet Gynecol 97: 142148

    Article  CAS  Google Scholar 

  • Vainio M, Kujansuu E, Iso-Mustarjarvi M, Maenpaa J (2002) Low dose acetylsalicylic acid in prevention of pregnancy-induced hypertension and intrauterine growth retardation in women with bilateral uterine artery notches. BJOG. 109(2): 1617

    Article  CAS  PubMed  Google Scholar 

  • Vainio M, Kujansuu E, Koivisto A, Mäenpää J (2005) Bilateral notching of uterine arteries at 12 - 14 weeks of gestation for prediction of hypertensive disorders of pregnancy. Acta Obstet Gynecol Scand 84: 10621067

    Article  PubMed  Google Scholar 

  • Wallenberg HCS, Hutchinson DL, Schuler HM, Stolte LA, Janssens J (1973) The pathogenesis of placental infarction. Am J Obstet Gynecol 117: 841846

    Google Scholar 

  • Yu C, Smith G, Papageorghiu A, Cacho A, Nicolaides K (2005) An integrated model for the prediction of preeclampsia using maternal factors and uterine artery Doppler velocimetry in unselected low-risk women. Am J Obstet Gynecol 193: 429436

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Klinik für Gynäkologie, Geburtshilfe und Reproduktionsmedizin, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover

    Prof. Dr. med. C. S. von Kaisenberg

  2. Universitätsklinik für Frauenheilkunde und Geburtshilfe, Paracelsus Medizinische Privatuniversität, Müllner Hauptstraße 48, 5020, Salzburg, Österreich

    Prof. Dr. med. H. Steiner

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  1. Prof. Dr. med. C. S. von Kaisenberg
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  2. Prof. Dr. med. H. Steiner
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Editors and Affiliations

  1. Paracelsus Medizinische Privatuniversität, Salzburg, Österreich

    Horst Steiner

  2. Klinikum rechts der Isar, München

    Karl-Theo M. Schneider

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von Kaisenberg, C., Steiner, H. (2012). Plazentationsstörungen und feto-maternale Erkrankungen. In: Steiner, H., Schneider, KT. (eds) Dopplersonographie in Geburtshilfe und Gynäkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20938-3_9

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  • DOI: https://doi.org/10.1007/978-3-642-20938-3_9

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