Skip to main content

Phytonutrient and Phytotherapy for Improving Health

  • Chapter
  • First Online:
Aesthetic Medicine
  • 4235 Accesses

Abstract

Advancing scientific research and increasing knowledge on medicine and food nutrition has dramatically changed the concepts about food, medicine, and healthcare and brought in a revolution on them in past decades. Strong recommendations by nutrition or clinical professionals to consume nutraceuticals and phytonutrients have become progressively popular. Alternative therapeutics based on nutrace AU: In the abstract please check the sentence starting “Alternative therapeutics …” for completeness. The author discusses phytonutrients and phytotherapy as well as the health benefits of phytonutrients and phytotherapy. Herbs and multiple component herbal formulations are described as well as their aesthetic benefits.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Zhao J (2007) Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: a perspective on plant biotechnology application. Recent Pat Biotechnol 1(1):74–97

    Article  Google Scholar 

  2. Bland JS (1996) Phytonutrition, phytotherapy, and phytopharmacology. Altern Ther Health Med 2(6):73–76

    PubMed  CAS  Google Scholar 

  3. Eussen S, Klungel O, Garssen J, Verhagen H, van Kranen H, van Loveren H, Rompelberg C (2010) Support of drug therapy using functional foods and dietary supplements: focus on statin therapy. Br J Nutr 103(9):1260–1277

    Article  PubMed  CAS  Google Scholar 

  4. Ornish D, Weidner G, Fair WR, Marlin R, Pettengill EB, Raisin CJ, Dunn-Emke S, Crutchfield L, Jacobs FN, Barnard RJ, Aronson WJ, McCormac P, McKnight DJ, Fein JD, Dnistrian AM, Weinstein J, Ngo TH, Mendell NR, Carroll PR (2005) Intensive lifestyle changes may affect the progression of prostate cancer. J Urol 174(3):1065–1069

    Article  PubMed  Google Scholar 

  5. Chan JM, Holick CN, Leitzmann MF, Rimm EB, Willett WC, Stampfer MJ, Giovannucci EL (2006) Diet after diagnosis and the risk of prostate cancer progression, recurrence, and death (United States). Cancer Causes Control 17(2):199–208

    Article  PubMed  Google Scholar 

  6. Ornish D, Magbanua MJ, Weidner G, Weinberg V, Kemp C, Green C, Mattie MD, Marlin R, Simko J, Shinohara K, Haqq CM, Carroll PR (2008) Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention. Proc Natl Acad Sci USA 105(24):8369–8374

    Article  PubMed  CAS  Google Scholar 

  7. Schmidt B, Ribnicky DM, Poulev A, Logendra S, Cefalu WT, Raskin I (2008) A natural history of botanical therapeutics. Metabolism 57(7 suppl 1):S3–S9

    Article  PubMed  CAS  Google Scholar 

  8. Graziose R, Lila MA, Raskin I (2010) Merging traditional Chinese medicine with modern drug discovery technologies to find novel drugs and functional foods. Curr Drug Discov Technol 7(1):2–12

    Article  PubMed  CAS  Google Scholar 

  9. Grunberger G, Jen KL, Artiss JD (2007) The benefits of early intervention in obese diabetic patients with FBCx: a new dietary fibre. Diabetes Metab Res Rev 23(1):56–62

    Article  PubMed  CAS  Google Scholar 

  10. Mancuso C, Barone E (2009) Curcumin in clinical practice: myth or reality? Trends Pharmacol Sci 30(7):333–334

    Article  PubMed  CAS  Google Scholar 

  11. Milder IE, Arts IC, van de Putte B, Venema DP, Hollman PC (2005) Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol. Br J Nutr 93(3):393–402

    Article  PubMed  CAS  Google Scholar 

  12. Pasinetti GM, Ho L (2010) Role of grape seed polyphenols in Alzheimer’s disease neuropathology. Nutr Diet Suppl 2:97–103

    Article  Google Scholar 

  13. Plosch T, Kruit JK, Bloks VW, Huijkman NC, Havinga R, Duchateau GS, Lin Y, Kuipers F (2006) Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter. J Nutr 136(8):2135–2140

    PubMed  Google Scholar 

  14. Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KF, Griel AE, Etherton TD (2002) Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 113(suppl 9B):71S–88S

    Article  PubMed  CAS  Google Scholar 

  15. Nöthlings U, Murphy SP, Wilkens LR, Henderson BE, Kolonel LN (2007) Flavonols and pancreatic cancer risk: the multiethnic cohort study. Am J Epidemiol 166(8):924–931

    Article  PubMed  Google Scholar 

  16. Duncan JL, Aleman TS, Gardner LM, De Castro E, Marks DA, Emmons JM, Bieber ML, Steinberg JD, Bennett J, Stone EM, MacDonald IM, Cideciyan AV, Maguire MG, Jacobson SG (2002) Macular pigment and lutein supplementation in choroideremia. Exp Eye Res 74(3):371–381

    Article  PubMed  CAS  Google Scholar 

  17. Hallund J, Bugel S, Tholstrup T, Ferrari M, Talbot D, Hall WL, Reimann M, Williams CM, Wiinberg N (2006) Soya isoflavone-enriched cereal bars affect markers of endothelial function in postmenopausal women. Br J Nutr 95(6):1120–1126

    Article  PubMed  CAS  Google Scholar 

  18. Kong KW, Khoo HE, Prasad KN, Ismail A, Tan CP, Rajab NF (2010) Revealing the power of the natural red pigment lycopene. Molecules 15(2):959–987

    Article  PubMed  CAS  Google Scholar 

  19. Zhao J (2007) Plant troponoids: chemistry, biological activity, and biosynthesis. Curr Med Chem 14(24):2597–2621

    Article  PubMed  CAS  Google Scholar 

  20. Balint GA (2001) Artemisinin and its derivatives: an important new class of antimalarial agents. Pharmacol Ther 90(2–3):261–265

    Article  PubMed  CAS  Google Scholar 

  21. Marangoni F, Poli A (2010) Phytosterols and cardiovascular health. Pharmacol Res 61(3):193–199

    Article  PubMed  CAS  Google Scholar 

  22. Rideout TC, Harding SV, Jones PJ (2010) Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6 J mice. Mol Nutr Food Res 54(suppl 1):S7–S13

    Article  PubMed  CAS  Google Scholar 

  23. Heinrichs SC (2010) Dietary omega-3 fatty acid supplementation for optimizing neuronal structure and function. Mol Nutr Food Res 54(4):447–456

    Article  PubMed  CAS  Google Scholar 

  24. Lopez-Huertas E (2010) Health effects of oleic acid and long chain omega-3 fatty acids (EPA and DHA) enriched milks. A review of intervention studies. Pharmacol Res 61(3):200–207

    Article  PubMed  CAS  Google Scholar 

  25. Psota TL, Gebauer SK, Kris-Etherton P (2006) Dietary omega-3 fatty acid intake and cardiovascular risk. Am J Cardiol 98(4A):3i–8i

    Article  PubMed  CAS  Google Scholar 

  26. Nagao K, Yanagita T (2010) Medium-chain fatty acids: functional lipids for the prevention and treatment of the metabolic syndrome. Pharmacol Res 61(3):208–212

    Article  PubMed  CAS  Google Scholar 

  27. Martena B, Pfeuffer M, Schrezenmeir J (2006) Medium-chain triglycerides. Int Dairy J 16:1374–1382

    Article  Google Scholar 

  28. Fürst P, Stehle P (2004) What are the essential elements needed for the determination of amino acid requirements in humans? J Nutr 134(6 suppl):1558S–1565S

    PubMed  Google Scholar 

  29. McDougall J (2002) Plant foods have a complete amino acid composition. Circulation 105(25):e197

    Article  PubMed  Google Scholar 

  30. Bhathena SJ, Velasquez MT (2002) Beneficial role of dietary phytoestrogens in obesity and diabetes. Am J Clin Nutr 76(6):1191–1201

    PubMed  CAS  Google Scholar 

  31. Lotito SB, Frei B (2006) Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic Biol Med 41(12):1727–1746

    Article  PubMed  CAS  Google Scholar 

  32. Chen ZY, Peng C, Jiao R, Wong YM, Yang N, Huang Y (2009) Anti-hypertensive nutraceuticals and functional foods. J Agric Food Chem 57(11):4485–4499

    Article  PubMed  CAS  Google Scholar 

  33. Rosch W, Liebregts T, Gundermann KJ, Vinson B, Holtmann G (2006) Phytotherapy for functional dyspepsia: a review of the clinical evidence for the herbal preparation STW5. Phytomedicine 13(suppl 5):114–121

    Article  PubMed  Google Scholar 

  34. Hijikata Y, Yasuhara A, Yoshida Y, Sento S (2006) Traditional Chinese medicine treatment of epilepsy. J Altern Complement Med 12(7):673–677

    Article  PubMed  Google Scholar 

  35. Rosenbaum CC, O’Mathúna DP, Chavez M, Shields K (2010) Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis. Altern Ther Health Med 16(2):32–40

    PubMed  Google Scholar 

  36. Saxena VS, Venkateshwarlu K, Nadig P, Barbhaiya HC, Bhatia N, Borkar DM, Gill RS, Jain RK, Katiyar SK, Nagendra Prasad KV, Nalinesha KM, Nasiruddin K, Rishi JP, Roy Chowdhury J, Saharia PS, Thomas B, Bagchi D (2004) Multicenter clinical trials on a novel polyherbal formulation in allergic rhinitis. Int J Clin Pharmacol Res 24(2–4):79–94

    PubMed  CAS  Google Scholar 

  37. Xue CC, Thien FC, Zhang JJ, Da Costa C, Li CG (2003) Treatment for seasonal allergic rhinitis by Chinese herbal medicine: a randomized placebo controlled trial. Altern Ther Health Med 9(5):80–87

    PubMed  Google Scholar 

  38. Kaufeler R, Polasek W, Brattstrom A, Koetter U (2006) Efficacy and safety of butterbur herbal extract Ze 339 in seasonal allergic rhinitis: postmarketing surveillance study. Adv Ther 23(2):373–384

    Article  PubMed  Google Scholar 

  39. Wagner H (2006) Multitarget therapy – the future of treatment for more than just functional dyspepsia. Phytomedicine 13(suppl 5):122–129

    Article  PubMed  Google Scholar 

  40. Agbabiaka TB, Pittler MH, Wider B, Ernst E (2009) Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 32(8):637–647

    Article  PubMed  Google Scholar 

  41. Tacklind J, MacDonald R, Rutks I, Wilt TJ. (2009) Serenoa repens for benign prostatic hyperplasia. Cochrane Database Syst Rev 2:CD001423

    Google Scholar 

  42. Roy S, Rink C, Khanna S, Phillips C, Bagchi D, Bagchi M, Sen CK (2004) Body weight and abdominal fat gene expression profile in response to a novel hydroxycitric acid-based dietary supplement. Gene Expr 11(5–6):251–262

    PubMed  Google Scholar 

  43. Demonty I, Ras RT, van der Knaap HC, Duchateau GS, Meijer L, Zock PL, Geleijnse JM, Trautwein EA (2009) Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake. J Nutr 139(2):271–284

    PubMed  CAS  Google Scholar 

  44. Stohs SJ, Preuss HG, Ohia SE, Kaats GR, Keen CL, Williams LD, Burdock GA (2009) No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol 15(14):4087–4089

    Article  PubMed  Google Scholar 

  45. Shiffman MA (2001) Warning about herbals in plastic and cosmetic surgery. Plast Reconstr Surg 108(7):2180–2181

    Article  PubMed  CAS  Google Scholar 

  46. Shiffman MA (2007) Facial aging: a clinical classification. Indian J Plast Surg 40(2):178–180

    Article  Google Scholar 

  47. Rahm D (2005) Perioperative nutrition and nutritional supplements. Plast Surg Nurs 25(1):21–28

    PubMed  Google Scholar 

  48. Ang-Lee MK, Moss J, Yuan CS (2001) Herbal medicines and perioperative care. J Am Med Assoc 286(2):208–216

    Article  CAS  Google Scholar 

  49. Rowe DJ, Baker AC (2009) Perioperative risks and benefits of herbal supplements in aesthetic surgery. Aesthet Surg J 29(2):150–157

    Article  PubMed  Google Scholar 

  50. Heller J, Gabbay JS, Ghadjar K, Jourabchi M, O’Hara C, Heller M, Bradley JP (2006) Top-10 list of herbal and supplemental medicines used by cosmetic patients: what the plastic surgeon needs to know. Plast Reconstr Surg 117(2):436–445

    Article  PubMed  CAS  Google Scholar 

  51. Manach C, Williamson G, Morand C, Scalbert A, Rémésy C (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81(1 suppl):230S–242S

    PubMed  CAS  Google Scholar 

  52. Laparra JM, Sanz Y (2010) Interactions of gut microbiota with functional food components and nutraceuticals. Pharmacol Res 61(3):219–225

    Article  PubMed  CAS  Google Scholar 

  53. Spencer JP, Schroeter H, Kuhnle G, Srai SK, Tyrrell RM, Hahn U, Rice-Evans C (2001) Epicatechin and its in vivo metabolite, 3’-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation. Biochem J 354(Pt 3):493–500

    Article  PubMed  CAS  Google Scholar 

  54. McGhie TK, Walton MC (2007) The bioavailability and absorption of anthocyanins: towards a better understanding. Mol Nutr Food Res 51(6):702–713

    Article  PubMed  CAS  Google Scholar 

  55. Gurley BJ, Swain A, Hubbard MA, Williams DK, Barone G, Hartsfield F, Tong Y, Carrier DJ, Cheboyina S, Battu SK (2008) Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St John’s Wort, and Echinacea. Mol Nutr Food Res 52(7):755–763

    Article  PubMed  CAS  Google Scholar 

  56. Brazier NC, Levine MA (2003) Drug-herb interaction among commonly used conventional medicines: a compendium for health care professionals. Am J Ther 10(3):163–169

    Article  PubMed  Google Scholar 

  57. Brand W, Schutte ME, Williamson G, van Zanden JJ, Cnubben NH, Groten JP, van Bladeren PJ, Rietjens IM (2006) Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients. Biomed Pharmacother 60(9):508–519

    Article  PubMed  CAS  Google Scholar 

  58. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST (2008) Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. J Am Med Assoc 300(24):2867–2878

    Article  CAS  Google Scholar 

  59. Ribnicky DM, Poulev A, Schmidt B, Cefalu WT, Raskin I (2008) Evaluation of botanicals for improving human health. Am J Clin Nutr 87(2):472S–475S

    PubMed  CAS  Google Scholar 

  60. Blundell J (2010) Making claims: functional foods for managing appetite and weight. Nat Rev Endocrinol 6(1):53–56

    Article  PubMed  Google Scholar 

  61. Bino RJ, Hall RD, Fiehn O, Kopka J, Saito K, Draper J, Nikolau BJ, Mendes P, Roessner-Tunali U, Beale MH, Trethewey RN, Lange BM, Wurtele ES, Sumner LW (2004) Potential of metabolomics as a functional genomics tool. Trends Plant Sci 9(9):418–425

    Article  PubMed  CAS  Google Scholar 

  62. Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B (2005) Metabolomics in human nutrition: opportunities and challenges. Am J Clin Nutr 82(3):497–503

    PubMed  CAS  Google Scholar 

  63. Astle J, Ferguson JT, German JB, Harrigan GG, Kelleher NL, Kodadek T, Parks BA, Roth MJ, Singletary KW, Wenger CD, Mahady GB (2007) Characterization of proteomic and metabolomic responses to dietary factors and supplements. J Nutr 137(12):2787–2793

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jian Zhao .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Zhao, J. (2012). Phytonutrient and Phytotherapy for Improving Health. In: Prendergast, P., Shiffman, M. (eds) Aesthetic Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20113-4_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-20113-4_6

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-20112-7

  • Online ISBN: 978-3-642-20113-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics